(Q35079996)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25677816%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase (English)

1 reference

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29 February 2020

1 reference

8

1 reference

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29 February 2020

13

William E Grizzle

1 reference

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29 February 2020

author name string

Pulin Che

1

1 reference

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29 February 2020

Youfeng Yang

2

1 reference

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29 February 2020

Xiaosi Han

3

1 reference

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29 February 2020

Meng Hu

4

1 reference

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29 February 2020

Jeffery C Sellers

5

1 reference

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29 February 2020

Angelina I Londono-Joshi

6

1 reference

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29 February 2020

Guo-Qiang Cai

7

1 reference

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29 February 2020

John D Christein

9

1 reference

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29 February 2020

Qinjiu Tang

10

1 reference

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29 February 2020

Dongquan Chen

11

1 reference

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29 February 2020

Qianjun Li

12

1 reference

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29 February 2020

Yin Ying Lu

14

1 reference

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29 February 2020

Qiang Ding

15

1 reference

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29 February 2020

language of work or name

English

0 references

publication date

13 February 2015

1 reference

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29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25677816%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

5

1 reference

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29 February 2020

page(s)

8453

1 reference

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Creative Commons Attribution 4.0 International

29 February 2020

copyright license

start time

13 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sonic hedgehog-Gli1 signaling pathway regulates the epithelial mesenchymal transition (EMT) by mediating a new target gene, S100A4, in pancreatic cancer cells

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S100A4 silencing suppresses proliferation, angiogenesis and invasion of thyroid cancer cells through downregulation of MMP-9 and VEGF.

8 July 2018

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S100A4 interacts with p53 in the nucleus and promotes p53 degradation

8 July 2018

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8 July 2018

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S100A4 siRNA inhibits human pancreatic cancer cell invasion in vitro

8 July 2018

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Neuronal Wiskott-Aldrich syndrome protein (N-WASP) is critical for formation of α-smooth muscle actin filaments during myofibroblast differentiation

8 July 2018

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Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27

8 July 2018

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S100A4 calcium-binding protein is key player in tumor progression and metastasis: preclinical and clinical evidence

8 July 2018

1 reference

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Regulation of SRC family kinases in human cancers

8 July 2018

1 reference

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8 July 2018

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Oncogenic Ras/Src cooperativity in pancreatic neoplasia.

8 July 2018

1 reference

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KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model

8 July 2018

1 reference

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Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts

8 July 2018

1 reference

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S100A4 and metastasis: a small actor playing many roles

8 July 2018

1 reference

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Caspases and kinases in a death grip

8 July 2018

1 reference

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Caspases in apoptosis and beyond

8 July 2018

1 reference

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Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

VEGF inhibition: insights from preclinical and clinical studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Prognostic significance of S100A4 and vascular endothelial growth factor expression in pancreatic cancer

8 July 2018

1 reference

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TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.

8 July 2018

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S100A4 contributes to the suppression of BNIP3 expression, chemoresistance, and inhibition of apoptosis in pancreatic cancer

8 July 2018

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S100A4 accelerates tumorigenesis and invasion of human prostate cancer through the transcriptional regulation of matrix metalloproteinase 9

8 July 2018

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S100A4, a mediator of metastasis

8 July 2018

1 reference

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The metastasis associated protein S100A4: role in tumour progression and metastasis

8 July 2018

1 reference

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p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain

8 July 2018

1 reference

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Yin Yang 1 is a negative regulator of p53.

8 July 2018

1 reference

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Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells

8 July 2018

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Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

8 July 2018

1 reference

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Focal adhesion kinase: the first ten years

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

S100 proteins: structure, functions and pathology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Overexpression of S100A4 in pancreatic ductal adenocarcinomas is associated with poor differentiation and DNA hypomethylation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

The metastasis-associated Mts1(S100A4) protein could act as an angiogenic factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Signaling through focal adhesion kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Insights into Src kinase functions: structural comparisons

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Cellular functions regulated by Src family kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Tumor measurement in the nude mouse

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Isolation and characterization of a gene specifically expressed in different metastatic cells and whose deduced gene product has a high degree of homology to a Ca2+-binding protein family

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Determination of subcutaneous tumor size in athymic (nude) mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Evaluation of the clinical significance of focal adhesion kinase and SRC expression in human pancreatic ductal adenocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Expression of S100A4 and Met: potential predictors for metastasis and survival in early-stage breast cancer.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin versus vitronectin

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

Protein S100A4: too long overlooked by pathologists?

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

TGF-beta1 up-regulates paxillin protein expression in malignant astrocytoma cells: requirement for a fibronectin substrate

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4326725

A phase I/II study of the Src inhibitor saracatinib (AZD0530) in combination with gemcitabine in advanced pancreatic cancer

27 September 2018

1 reference

12 December 2020

Stimulation of cell migration by overexpression of focal adhesion kinase and its association with Src and Fyn

1 reference

12 December 2020

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

12 December 2020

Differential expression of S100A2 and S100A4 during progression of human prostate adenocarcinoma

1 reference

12 December 2020

Increased S100A4 expression combined with decreased E-cadherin expression predicts a poor outcome of patients with pancreatic cancer

1 reference

12 December 2020

Nuclear expression of S100A4 is associated with aggressive behavior of epithelial ovarian carcinoma: an important autocrine/paracrine factor in tumor progression

1 reference

12 December 2020

Association of S100A4 and osteopontin with specific prognostic factors and survival of patients with minimally invasive breast cancer

1 reference

12 December 2020

High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP08453

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25677816%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25677816%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25677816

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25677816%20AND%20SRC:MED&resulttype=core&format=json