(Q35080414)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

3

1 reference

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30 December 2019

14

Peggy L Porter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Inke Timmerbeul

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Carrie M Garrett-Engele

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Xueyan Chen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Eduardo Firpo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Viktor Grünwald

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Kenji Kamino

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Ludwig Wilkens

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Ulrich Lehmann

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Jan Buer

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Robert Geffers

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Stefan Kubicka

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Michael P Manns

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

James M Roberts

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Nisar P Malek

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

11 September 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

14009-14014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Cooperative regulation of the cell division cycle by the protein kinases RAF and AKT

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Skp2-dependent degradation of p27kip1 is essential for cell cycle progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

p27 as a target for cancer therapeutics

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27(Kip1) by PKB/Akt-mediated phosphorylation in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Regulation of the cdk inhibitor p27 and its deregulation in cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

CDK inhibitors: positive and negative regulators of G1-phase progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Role of p27Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Cyclin E-CDK2 is a regulator of p27Kip1.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1599904

Loss of CBP causes T cell lymphomagenesis in synergy with p27Kip1 insufficiency.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

PDGF-BB regulates p27 expression through ERK-dependent RNA turn-over in vascular smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

Skp2-mediated degradation of p27 regulates progression into mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0606316103

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Promoter hypermethylation of the death-associated protein kinase gene in breast cancer is associated with the invasive lobular subtype

1 reference

12 December 2020

High expression of Cks1 in human non-small cell lung carcinomas

1 reference

12 December 2020

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

1 reference

12 December 2020

Localization and expression of p27KIP1 in multistage colorectal carcinogenesis

1 reference

12 December 2020

Prognostic significance of p27(Kip1) expression in colorectal cancer: a clinico-pathological characterization

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0606316103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16966613%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

16966613

1 reference