(Q35097037)

6 August 2017

title

Planar cell polarity aligns osteoblast division in response to substrate strain (English)

1 reference

6 August 2017

0 references

Peter Delisser

5

0 references

Gabriel L Galea

Gabriel L Galea

1

0 references

Lee B Meakin

Lee B Meakin

2

0 references

Andrew J Copp

Andrew J Copp

7

0 references

Andre J van Wijnen

8

Andre J van Wijnen

1 reference

6 August 2017

6

Gary S Stein

1 reference

6 August 2017

4

Hanna Taipaleenmaki

1 reference

6 August 2017

Dawn Savery

3

1 reference

6 August 2017

Lance E Lanyon

9

1 reference

6 August 2017

Joanna S Price

10

1 reference

6 August 2017

publication date

1 March 2015

1 reference

Journal of Bone and Mineral Research

6 August 2017

published in

1 reference

6 August 2017

volume

30

1 reference

6 August 2017

issue

3

1 reference

6 August 2017

page(s)

423-435

1 reference

SaOS2 Osteosarcoma cells as an in vitro model for studying the transition of human osteoblasts to osteocytes.

6 August 2017

cites work

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9 July 2018

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Estrogen receptors' roles in the control of mechanically adaptive bone (re)modeling

9 July 2018

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Deletion of a single β-catenin allele in osteocytes abolishes the bone anabolic response to loading

9 July 2018

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Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity

9 July 2018

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Estrogen receptor α mediates proliferation of osteoblastic cells stimulated by estrogen and mechanical strain, but their acute down-regulation of the Wnt antagonist Sost is mediated by estrogen receptor β.

9 July 2018

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The Wnt coreceptor Ryk regulates Wnt/planar cell polarity by modulating the degradation of the core planar cell polarity component Vangl2.

9 July 2018

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Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2.

9 July 2018

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WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk

9 July 2018

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Activation of Wnt Planar Cell Polarity (PCP) signaling promotes growth plate column formation in vitro

9 July 2018

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Mechanical regulation of signaling pathways in bone

9 July 2018

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Bones' adaptive response to mechanical loading is essentially linear between the low strains associated with disuse and the high strains associated with the lamellar/woven bone transition

9 July 2018

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Comparison of phenotypes between different vangl2 mutants demonstrates dominant effects of the Looptail mutation during hair cell development

9 July 2018

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Sost downregulation and local Wnt signaling are required for the osteogenic response to mechanical loading.

9 July 2018

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Cell polarity: The missing link in skeletal morphogenesis?

9 July 2018

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Bone morphogenetic protein-2-induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension

9 July 2018

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Remodeling of actin cytoskeleton in mouse periosteal cells under mechanical loading induces periosteal cell proliferation during bone formation

9 July 2018

1 reference

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Sclerostin expression is induced by BMPs in human Saos-2 osteosarcoma cells but not via direct effects on the sclerostin gene promoter or ECR5 element

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

The cell cycle, including the mitotic cycle and organelle division cycles, as revealed by cytological observations

9 July 2018

1 reference

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Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity

9 July 2018

1 reference

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Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Type XII collagen regulates osteoblast polarity and communication during bone formation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Mechanical loading-related changes in osteocyte sclerostin expression in mice are more closely associated with the subsequent osteogenic response than the peak strains engendered

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Wnt5a: its signalling, functions and implication in diseases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Role of endocrine and paracrine factors in the adaptation of bone to mechanical loading

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Disruption of PCP signaling causes limb morphogenesis and skeletal defects and may underlie Robinow syndrome and brachydactyly type B.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Common themes in centriole and centrosome movements

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Oriented cell motility and division underlie early limb bud morphogenesis.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Cortical actin dynamics facilitate early-stage centrosome separation

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Binding of APC and dishevelled mediates Wnt5a-regulated focal adhesion dynamics in migrating cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

WNT5A mutations in patients with autosomal dominant Robinow syndrome

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Wnt5a regulates distinct signalling pathways by binding to Frizzled2

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Structural plasticity in actin and tubulin polymer dynamics

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

The planar cell polarity pathway directs parietal endoderm migration

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Mechanically induced osteogenic differentiation--the role of RhoA, ROCKII and cytoskeletal dynamics

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Beta-catenin levels influence rapid mechanical responses in osteoblasts

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Functional characterization of genetic variation in the Frizzled 1 (FZD1) promoter and association with bone phenotypes: more to the LRP5 story?

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Genetic interaction between members of the Vangl family causes neural tube defects in mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Activation of ROCK by RhoA is regulated by cell adhesion, shape, and cytoskeletal tension

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Wnt/beta-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor alpha

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

One mechanostat or many? Modifications of the site-specific response of bone to mechanical loading by nature and nurture

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Wnt signaling activation during bone regeneration and the role of Dishevelled in chondrocyte proliferation and differentiation.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

The Rho-associated protein kinase p160ROCK is required for centrosome positioning

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Bone "mass" and the "mechanostat": a proposal.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

Control of bone architecture by functional load bearing

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4333081

A Wolff in sheep's clothing: trabecular bone adaptation in response to changes in joint loading orientation

9 July 2018

1 reference

Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling

21 January 2018

1 reference

Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength

21 January 2018

1 reference

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation

21 January 2018

1 reference

Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A

21 January 2018

1 reference

WNT5A induces osteogenic differentiation of human adipose stem cells via rho-associated kinase ROCK.

21 January 2018

1 reference

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.

21 January 2018

1 reference

Developmental basis of severe neural tube defects in the loop-tail (Lp) mutant mouse: use of microsatellite DNA markers to identify embryonic genotype.

21 January 2018

1 reference

Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila.

21 January 2018

1 reference

Defective planar cell polarity in polycystic kidney disease

21 January 2018

1 reference

Dissection of sets of genes that control the character of wnt5a-deficient mouse calvarial cells

21 January 2018

1 reference

Mechanical strain differentially regulates endothelial nitric-oxide synthase and receptor activator of nuclear kappa B ligand expression via ERK1/2 MAPK.

21 January 2018

1 reference

Blockade of beta-adrenergic signaling does not influence the bone mechano-adaptive response in mice.

21 January 2018

1 reference

Absence of mechanical loading in utero influences bone mass and architecture but not innervation in Myod-Myf5-deficient mice.

21 January 2018

1 reference

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice

21 January 2018

1 reference

Elastic anisotropy and collagen orientation of osteonal bone are dependent on the mechanical strain distribution

21 January 2018

1 reference

12 December 2020

Quantification of age-related changes in the structure model type and trabecular thickness of human tibial cancellous bone

1 reference

12 December 2020

Missense polymorphisms of the WNT16 gene are associated with bone mass, hip geometry and fractures

1 reference

12 December 2020

1 reference

12 December 2020

Altered aggrecan synthesis correlates with cell and nucleus structure in statically compressed cartilage

1 reference

12 December 2020

Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities

1 reference

12 December 2020

Identifiers

DOI

10.1002/JBMR.2377

1 reference

6 August 2017

1 reference

6 August 2017

1 reference