(Q35116171)

6 August 2017

1 reference

title

Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics (English)

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6 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12718737

28 December 2023

1 reference

https://api.crossref.org/works/10.1517/14712598.3.1.127

28 December 2023

author name string

Kevin Pong

1

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 February 2003

1 reference

full work available at URL

6 August 2017

http://www.tandfonline.com/doi/pdf/10.1517/14712598.3.1.127

1 reference

https://api.crossref.org/works/10.1517/14712598.3.1.127

Expert Opinion on Biological Therapy

28 December 2023

published in

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6 August 2017

volume

3

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6 August 2017

issue

1

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6 August 2017

page(s)

127-139

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Extending functional life span

6 August 2017

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Superoxide anion radical (O2-.), superoxide dismutases, and related matters

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Lipid peroxidation in membranes and low-density lipoproteins: similarities and differences

21 January 2018

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Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells.

21 January 2018

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Antioxidants and oxidants regulated signal transduction pathways

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21 January 2018

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

21 January 2018

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FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

21 January 2018

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Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior

21 January 2018

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Oxidation of polyamines and brain injury

21 January 2018

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Methodological considerations and factors affecting 8-hydroxy-2-deoxyguanosine analysis

21 January 2018

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The association between neuronal nitric oxide synthase and neuronal sensitivity in the brain after brain injury

21 January 2018

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The significance of nitric oxide production in the brain after injury

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What synaptic lipid signaling tells us about seizure-induced damage and epileptogenesis

21 January 2018

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Regional vulnerability to endogenous and exogenous oxidative stress in organotypic hippocampal culture.

21 January 2018

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Vitamin E and beta-carotene protect against ethanol combined with ischemia in an embryonic rat hippocampal culture model of fetal alcohol syndrome

21 January 2018

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Neuroprotective efficacy of combination therapy with two different antioxidants in rats subjected to transient focal ischemia

21 January 2018

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Inhibition of iron-dependent and ischemia-induced brain damage by the alpha-tocopherol analogue MDL 74,722.

21 January 2018

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Synergistic protective effects of antioxidant and nitric oxide synthase inhibitor in transient focal ischemia

21 January 2018

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Pharmacologic properties of phenyl N-tert-butylnitrone

21 January 2018

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Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

21 January 2018

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Amelioration of hippocampal neuronal damage after global ischemia by neuronal overexpression of BCL-2 in transgenic mice.

21 January 2018

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Dietary vitamin C, beta-carotene and 30-year risk of stroke: results from the Western Electric Study

21 January 2018

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Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease

21 January 2018

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Ascorbate regulation and its neuroprotective role in the brain

21 January 2018

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Neuroprotective actions of selegiline

21 January 2018

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Glutathione, iron and Parkinson's disease

21 January 2018

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Mitochondrial involvement in Parkinson's disease

21 January 2018

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Models of repair mechanisms for future treatment modalities of Parkinson's disease.

21 January 2018

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Oxidative stress in neurodegeneration: mechanisms and therapeutic perspectives

21 January 2018

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Is cell aging caused by respiration-dependent injury to the mitochondrial genome?

21 January 2018

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Mitochondrial genetics: a paradigm for aging and degenerative diseases?

21 January 2018

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Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons.

21 January 2018

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Neuroprotective effects of estrogens: potential mechanisms of action

21 January 2018

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The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease

21 January 2018

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1-Methyl-4-phenylpyridine (MPP+) is toxic to mesencephalic dopamine neurons in culture

21 January 2018

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A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

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In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

21 January 2018

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1-Methyl-4-phenylpyridine (MPP+) induces oxidative stress in the rodent

21 January 2018

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Effects of MPTP, MPP+ and paraquat on mitochondrial potential and oxidative stress

21 January 2018

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Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

21 January 2018

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21 January 2018

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Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity

21 January 2018

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Impact of sustained deprenyl (selegiline) in levodopa-treated Parkinson's disease: a randomized placebo-controlled extension of the deprenyl and tocopherol antioxidative therapy of parkinsonism trial

21 January 2018

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

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Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

21 January 2018

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Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

21 January 2018

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21 January 2018

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Six important themes in amyotrophic lateral sclerosis (ALS) research, 1999.

21 January 2018

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Therapeutic benefits of putrescine-modified catalase in a transgenic mouse model of familial amyotrophic lateral sclerosis

21 January 2018

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Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells

21 January 2018

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Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

21 January 2018

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Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice

21 January 2018

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Coenzyme Q10 as a possible treatment for neurodegenerative diseases

21 January 2018

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Effects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary results.

21 January 2018

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Effect of creatine supplementation on metabolite levels in ALS motor cortices

21 January 2018

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A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

21 January 2018

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Requirement for superoxide in excitotoxic cell death.

21 January 2018

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Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation

21 January 2018

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Mitochondrial superoxide production in kainate-induced hippocampal damage.

21 January 2018

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Protein and DNA oxidation in spinal injury: neurofilaments--an oxidation target

21 January 2018

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Metalloporphyrin class of therapeutic catalytic antioxidants

21 January 2018

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beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger

21 January 2018

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Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons

21 January 2018

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Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons

21 January 2018

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Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures

21 January 2018

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Attenuation of zinc-induced intracellular dysfunction and neurotoxicity by a synthetic superoxide dismutase/catalase mimetic, in cultured cortical neurons

21 January 2018

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EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

21 January 2018

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Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies

21 January 2018

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Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

21 January 2018

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Why do neuroprotective drugs that are so promising in animals fail in the clinic? An industry perspective

21 January 2018

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Pharmacological interventions for stroke: failures and future

21 January 2018

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Antioxidant Profile and Early Outcome in Stroke Patients

21 January 2018

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Aging: phenomena and theories

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28 December 2023

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Calorie restriction enhances the expression of key metabolic enzymes associated with protein renewal during aging

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28 December 2023

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28 December 2023

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Understanding cell death in Parkinson's disease

28 December 2023

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Oestrogen as a neuroprotective hormone

28 December 2023

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Ovarian steroids and raloxifene prevent MPTP-induced dopamine depletion in mice

28 December 2023

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Estrogen reduces acute striatal dopamine responses in vivo to the neurotoxin MPP+ in female, but not male rats

28 December 2023

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MPTP-induced deficits in motor activity: neuroprotective effects of the spintrapping agent, alpha-phenyl-tert-butyl-nitrone (PBN)

28 December 2023

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Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

28 December 2023

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1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.

28 December 2023

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Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

28 December 2023

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Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L.

28 December 2023

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Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis

28 December 2023

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Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

28 December 2023

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Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis

28 December 2023

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Benefit of a combined treatment with trientine and ascorbate in familial amyotrophic lateral sclerosis model mice

28 December 2023

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The 21-aminosteroid U-74389F attenuates hyperexpression of GAP-43 and NADPH-diaphorase in the spinal cord of wobbler mouse, a model for amyotrophic lateral sclerosis

28 December 2023

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Blood oxidative stress in amyotrophic lateral sclerosis

28 December 2023

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Creatine monohydrate in muscular dystrophies: A double-blind, placebo-controlled clinical study

28 December 2023

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A randomized, controlled trial of creatine monohydrate in patients with mitochondrial cytopathies

28 December 2023

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A mimic of superoxide dismutase activity based upon desferrioxamine B and manganese(IV)

28 December 2023

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Salen-manganese complexes are superoxide dismutase-mimics

28 December 2023

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Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy

28 December 2023

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A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced lung injury in vivo

28 December 2023

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Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury

28 December 2023

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A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats

28 December 2023

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Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model

28 December 2023

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Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics.

28 December 2023

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28 December 2023

Identifiers

1 reference

6 August 2017

1 reference