(Q35129455)

6 August 2017

title

Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation (English)

1 reference

6 August 2017

0 references

0 references

Guo Zhang

2

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author name string

Hai Zhang

1

1 reference

6 August 2017

Frank J Gonzalez

3

1 reference

6 August 2017

Sung-Min Park

4

1 reference

6 August 2017

Dongsheng Cai

5

1 reference

6 August 2017

language of work or name

English

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publication date

26 July 2011

1 reference

6 August 2017

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6 August 2017

volume

9

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6 August 2017

issue

7

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6 August 2017

page(s)

e1001112

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Creative Commons Attribution 4.0 International

6 August 2017

copyright license

start time

26 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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13 July 2018

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A role for hypothalamic malonyl-CoA in the control of food intake

13 July 2018

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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PI3K integrates the action of insulin and leptin on hypothalamic neurons

13 July 2018

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13 July 2018

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IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

13 July 2018

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13 July 2018

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

13 July 2018

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C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase

13 July 2018

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Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha

13 July 2018

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TSC2 mediates cellular energy response to control cell growth and survival

13 July 2018

1 reference

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13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

13 July 2018

1 reference

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13 July 2018

1 reference

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Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1alpha

13 July 2018

1 reference

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Activation of downstream signals by the long form of the leptin receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Central nervous system control of food intake

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Genetics of body-weight regulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Divergent signaling capacities of the long and short isoforms of the leptin receptor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Neuronal regulation of homeostasis by nutrient sensing

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Hypoxia, HIF1 and glucose metabolism in the solid tumour

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Endoplasmic reticulum stress plays a central role in development of leptin resistance

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Neuronal PTP1B regulates body weight, adiposity and leptin action.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Diabetes, obesity, and the brain

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

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27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Neuroscience. The fat-brain axis enters a new dimension

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Brain glucosensing and the K(ATP) channel

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144184

Generation of a dominant-negative mutant of endothelial PAS domain protein 1 by deletion of a potent C-terminal transactivation domain

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21814490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21814490

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PBIO.1001112

1 reference

6 August 2017

1 reference

6 August 2017

1 reference