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Adaptor proteins in lymphocyte activation.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Adaptor proteins in lymphocyte activation
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author
Erin Janssen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
author name string
Weiguo Zhang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
publication date
1 June 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
published in
Current Opinion in Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
volume
15
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
page(s)
269-276
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
cites work
Signaling through scaffold, anchoring, and adaptor proteins
1 reference
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7 January 2021
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Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins
1 reference
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Crossref
reference URL
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7 January 2021
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Signalling scaffolds and adaptors in T-cell immunity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adapters in lymphocyte signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of B-cell signal transduction by adaptor proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
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Scaffolds, adaptors and linkers of TCR signaling: theory and practice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Positive and negative regulation of T-cell activation by adaptor proteins
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
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The role of membrane-associated adaptors in T cell receptor signalling
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Crossref
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7 January 2021
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Essential role of LAT in T cell development
1 reference
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Crossref
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7 January 2021
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Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development
1 reference
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Crossref
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7 January 2021
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Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
1 reference
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Crossref
reference URL
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7 January 2021
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A LAT mutation that inhibits T cell development yet induces lymphoproliferation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
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inferred from DOI database lookup
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
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Displacement of linker for activation of T cells from the plasma membrane due to redox balance alterations results in hyporesponsiveness of synovial fluid T lymphocytes in rheumatoid arthritis
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
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Effect of redox balance alterations on cellular localization of LAT and downstream T-cell receptor signaling pathways
1 reference
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Crossref
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7 January 2021
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A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirement for SLP-76 domains in T cell development and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential role of SLP-76 domains in T cell development and function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for the SLP-76 adaptor GADS in T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic regulation of immunoreceptor signaling by SLP-76-related adaptor Clnk and serine/threonine protein kinase HPK-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
BLNK: molecular scaffolding through 'cis'-mediated organization of signaling proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Src homology region 2 domain-containing phosphatase 1 positively regulates B cell receptor-induced apoptosis by modulating association of B cell linker protein with Nck and activation of c-Jun NH2-terminal kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor-facilitated antigen presentation requires the recruitment of B cell linker protein to Igalpha
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
The direct recruitment of BLNK to immunoglobulin alpha couples the B-cell antigen receptor to distal signaling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
LAB: a new membrane-associated adaptor molecule in B cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of T cell signaling networks and development by Grb2 haploid insufficiency.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Grap negatively regulates T-cell receptor-elicited lymphocyte proliferation and interleukin-2 induction.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
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7 January 2021
based on heuristic
inferred from DOI database lookup
Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Shc with Grb2 regulates the Grb2 association with mSOS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A nonredundant role for the adapter protein Shc in thymic T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: Fyn is essential for tyrosine phosphorylation of Csk-binding protein/phosphoprotein associated with glycolipid-enriched microdomains in lipid rafts in resting T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SLAP, a dimeric adapter protein, plays a functional role in T cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl and Cbl-b in T-cell regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl: many adaptations to regulate protein tyrosine kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of Lck by Cbl ubiquitin ligase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of the high-affinity IgE receptor results in the tyrosine phosphorylation of a 60 kD protein which is associated with the protein-tyrosine kinase, Csk
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dok-related protein negatively regulates T cell development via its RasGTPase-activating protein and Nck docking sites
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a novel member of the DOK family that binds and modulates Abl signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DOK4 and DOK5: new Dok-related genes expressed in human T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0952-7915%2803%2900044-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0952-7915(03)00044-X
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
PubMed publication ID
12787751
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12787751
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12787751%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 November 2019
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