(Q35155498)

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Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice

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5 March 2020

Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879458%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

traumatic brain injury

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cognitive dysfunction

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based on heuristic

inferred from title

3

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5 March 2020

author name string

Renana Baratz

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5 March 2020

David Tweedie

2

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5 March 2020

Vardit Rubovitch

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5 March 2020

Weiming Luo

5

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5 March 2020

Barry J Hoffer

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5 March 2020

Nigel H Greig

7

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5 March 2020

Chaim G Pick

8

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publication date

7 March 2015

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5 March 2020

Journal of Neuroinflammation

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5 March 2020

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5 March 2020

45

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5 March 2020

copyright license

Creative Commons Attribution 4.0 International

7 March 2015

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April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s12974-015-0237-4

0 references

Studies of selective TNF inhibitors in the treatment of brain injury from stroke and trauma: a review of the evidence to date

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13 July 2018

Dementia risk after traumatic brain injury vs nonbrain trauma: the role of age and severity

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Traumatic brain injury and risk of dementia in older veterans

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Perispinal etanercept for post-stroke neurological and cognitive dysfunction: scientific rationale and current evidence

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13 July 2018

Critical role of TNF-α in cerebral aneurysm formation and progression to rupture

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13 July 2018

Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury

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13 July 2018

Network dysfunction after traumatic brain injury

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Pharmacotherapy of traumatic brain injury: state of the science and the road forward: report of the Department of Defense Neurotrauma Pharmacology Workgroup

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Structural basis of signal transduction in the TNF receptor superfamily

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13 July 2018

TNF-α induces phenotypic modulation in cerebral vascular smooth muscle cells: implications for cerebral aneurysm pathology

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Pomalidomide is nonteratogenic in chicken and zebrafish embryos and nonneurotoxic in vitro

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Microglia: a new frontier for synaptic plasticity, learning and memory, and neurodegenerative disease research.

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13 July 2018

Tumor necrosis factor in traumatic brain injury: effects of genetic deletion of p55 or p75 receptor

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13 July 2018

Changes in mouse cognition and hippocampal gene expression observed in a mild physical- and blast-traumatic brain injury

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13 July 2018

Structural plasticity in the dentate gyrus- revisiting a classic injury model

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13 July 2018

3,6'-dithiothalidomide improves experimental stroke outcome by suppressing neuroinflammation

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13 July 2018

Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states

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13 July 2018

Selective TNF inhibition for chronic stroke and traumatic brain injury: an observational study involving 629 consecutive patients treated with perispinal etanercept

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13 July 2018

Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice

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13 July 2018

TNFα in synaptic function: switching gears.

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13 July 2018

3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit

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13 July 2018

Tumor necrosis factor-α synthesis inhibitor 3,6'-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer's disease

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13 July 2018

Early intervention with a small molecule inhibitor for tumor necrosis factor-α prevents cognitive deficits in a triple transgenic mouse model of Alzheimer's disease

1 reference

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13 July 2018

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

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TNF-α protein synthesis inhibitor restores neuronal function and reverses cognitive deficits induced by chronic neuroinflammation.

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13 July 2018

Tumor necrosis factor-α synthesis inhibitor, 3,6'-dithiothalidomide, reverses behavioral impairments induced by minimal traumatic brain injury in mice

1 reference

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13 July 2018

Imipramine treatment improves cognitive outcome associated with enhanced hippocampal neurogenesis after traumatic brain injury in mice

1 reference

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Targeting TNF-α to elucidate and ameliorate neuroinflammation in neurodegenerative diseases

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The molecular pathophysiology of concussive brain injury

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Neuroprotection for traumatic brain injury: translational challenges and emerging therapeutic strategies

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Delayed reduction in hippocampal postsynaptic density protein-95 expression temporally correlates with cognitive dysfunction following controlled cortical impact in mice

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Genetic analysis of the role of tumor necrosis factor receptors in functional outcome after traumatic brain injury in mice

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Tumor necrosis factor-alpha mediated signaling in neuronal homeostasis and dysfunction

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In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury.

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13 July 2018

NCS-1 in the dentate gyrus promotes exploration, synaptic plasticity, and rapid acquisition of spatial memory

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Cell cycle activation and CNS injury.

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13 July 2018

Closed head injury in a mouse model results in molecular changes indicating inflammatory responses

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Systemic inflammatory response following acute traumatic brain injury

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Distinct cellular patterns of upregulated chemokine expression supporting a prominent inflammatory role in traumatic brain injury

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Minimal traumatic brain injury induce apoptotic cell death in mice.

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The predictive brain state: timing deficiency in traumatic brain injury?

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The impact of traumatic brain injuries: a global perspective.

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13 July 2018

TNF-alpha inhibition as a treatment strategy for neurodegenerative disorders: new drug candidates and targets.

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13 July 2018

The dentate gyrus: fundamental neuroanatomical organization (dentate gyrus for dummies)

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Outcome from mild traumatic brain injury

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13 July 2018

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pat

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Thiothalidomides: Novel Isosteric Analogues of Thalidomide with Enhanced TNF-α Inhibitory Activity

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13 July 2018

Closed-head minimal traumatic brain injury produces long-term cognitive deficits in mice

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13 July 2018

Tumor necrosis factor signaling.

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13 July 2018

Detrimental and beneficial effects of injury-induced inflammation and cytokine expression in the nervous system.

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13 July 2018

Inflammatory response in acute traumatic brain injury: a double-edged sword

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13 July 2018

Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury

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13 July 2018

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13 July 2018

Production of tumor necrosis factor-alpha and interleukin-1beta by human cerebral microvascular endothelium after percussive trauma.

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13 July 2018

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

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13 July 2018

Tumor necrosis factor (TNF) receptors in cellular signaling of soluble and membrane-expressed TNF.

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A review of the validity and variability of the elevated plus-maze as an animal model of anxiety

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13 July 2018

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

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13 July 2018

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

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13 July 2018

Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue.

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13 July 2018

Synergistic effects of traumatic head injury and apolipoprotein-epsilon 4 in patients with Alzheimer's disease.

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13 July 2018

A two-trial memory task with automated recording: study in young and aged rats

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13 July 2018

Reply to D’Amato et al. and Zeldis et al.: Screening of thalidomide derivatives in chicken and zebrafish embryos

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27 September 2018

A new roadmap for drug development for Alzheimer's disease

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27 September 2018

Pattern of cerebrospinal immediate early gene c-fos expression in an ovine model of non-accidental head injury.

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27 September 2018

Surveillance for traumatic brain injury-related deaths--United States, 1997-2007.

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27 September 2018

Long-term outcomes after uncomplicated mild traumatic brain injury: a comparison with trauma controls.

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27 September 2018

The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI).

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27 September 2018

Therapeutic evaluation of etanercept in a model of traumatic brain injury

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27 September 2018

Severity of controlled cortical impact traumatic brain injury in rats and mice dictates degree of behavioral deficits.

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27 September 2018

Effect of traumatic brain injury on cognitive function in mice lacking p55 and p75 tumor necrosis factor receptors.

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27 September 2018

Acute rolipram/thalidomide treatment improves tissue sparing and locomotion after experimental spinal cord injury

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27 September 2018

Effect of thalidomide on signal transduction pathways and secondary damage in experimental spinal cord trauma

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27 September 2018

Long-lasting sleep patterns of adult patients with minor traumatic brain injury (mTBI) and non-mTBI subjects.

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27 September 2018

TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

The characteristics of patients who do not seek medical treatment for traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Apoptotic and behavioral sequelae of mild brain trauma in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Apoptotic changes in the cortex and hippocampus following minimal brain trauma in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

The effect of thalidomide on spinal cord ischemia/reperfusion injury in a rabbit model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Mild traumatic brain injury induces persistent cognitive deficits and behavioral disturbances in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Outcomes and costs of acute treatment of traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Extending the spontaneous preference test of recognition: evidence of object-location and object-context recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Exacerbation of damage and altered NF-kappaB activation in mice lacking tumor necrosis factor receptors after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Object recognition in mice: improvement of memory by glucose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4352276

27 September 2018

The presence of tumour necrosis factor in CSF and plasma after severe head injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25879458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/25879458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25879458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Closed head injury--an inflammatory disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25879458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25879458

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12974-015-0237-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879458%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Dimensions Publication ID

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879458%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25879458%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

ResearchGate publication ID

0 references

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