(Q35163309)

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Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors

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scholarly article

1 reference

Europe PubMed Central

6 August 2017

Diversity-oriented synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors (English)

1 reference

Europe PubMed Central

6 August 2017

Plasmodium falciparum

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object named as

Kevin Galinsky

9

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16

object named as

Dyann F Wirth

1 reference

Europe PubMed Central

6 August 2017

Amanda K Lukens

1

object named as

Amanda K Lukens

1 reference

Europe PubMed Central

6 August 2017

Stuart Schreiber

14

object named as

Stuart L Schreiber

1 reference

Europe PubMed Central

6 August 2017

author name string

Richard W Heidebrecht

2

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Europe PubMed Central

6 August 2017

Carol Mulrooney

3

1 reference

Europe PubMed Central

6 August 2017

Jennifer A Beaudoin

4

1 reference

Europe PubMed Central

6 August 2017

Eamon Comer

5

1 reference

Europe PubMed Central

6 August 2017

Jeremy R Duvall

6

1 reference

Europe PubMed Central

6 August 2017

Mark E Fitzgerald

7

1 reference

Europe PubMed Central

6 August 2017

Daniela Masi

8

1 reference

Europe PubMed Central

6 August 2017

Christina A Scherer

10

1 reference

Europe PubMed Central

6 August 2017

Michelle Palmer

11

1 reference

Europe PubMed Central

6 August 2017

Benito Munoz

12

1 reference

Europe PubMed Central

6 August 2017

Michael Foley

13

1 reference

Europe PubMed Central

6 August 2017

Roger C Wiegand

15

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Europe PubMed Central

6 August 2017

language of work or name

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publication date

21 October 2014

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Europe PubMed Central

6 August 2017

Journal of Infectious Diseases

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Europe PubMed Central

6 August 2017

211

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Europe PubMed Central

6 August 2017

7

1 reference

Europe PubMed Central

6 August 2017

1097-1103

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Europe PubMed Central

6 August 2017

Diversity-oriented synthesis-facilitated medicinal chemistry: toward the development of novel antimalarial agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354981

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Quinolone-3-diarylethers: a new class of antimalarial drug.

1 reference

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Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosis

1 reference

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13 July 2018

HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.

1 reference

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13 July 2018

Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria

1 reference

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Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors

1 reference

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A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor

1 reference

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A framework for variation discovery and genotyping using next-generation DNA sequencing data

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A Research Agenda to Underpin Malaria Eradication

1 reference

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Grand challenge commentary: Accessing new chemical space for 'undruggable' targets

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An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors

1 reference

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Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354981

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The Sequence Alignment/Map format and SAMtools

1 reference

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Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

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Novel web-based tools combining chemistry informatics, biology and social networks for drug discovery

1 reference

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13 July 2018

PlasmoDB: a functional genomic database for malaria parasites

1 reference

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13 July 2018

Molecular basis of resistance to cytochrome bc1 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354981

13 July 2018

Assessment and continued validation of the malaria SYBR green I-based fluorescence assay for use in malaria drug screening

1 reference

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13 July 2018

Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

1 reference

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13 July 2018

A database of antimalarial drug resistance

1 reference

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13 July 2018

Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum

1 reference

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13 July 2018

Mutations in cytochrome b resulting in atovaquone resistance are associated with loss of fitness in Plasmodium falciparum

1 reference

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13 July 2018

Target-oriented and diversity-oriented organic synthesis in drug discovery

1 reference

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13 July 2018

Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4354981

13 July 2018

Human malaria parasites in continuous culture

1 reference

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Binding dynamics at the quinone reduction (Qi) site influence the equilibrium interactions of the iron sulfur protein and hydroquinone oxidation (Qo) site of the cytochrome bc1 complex

1 reference

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27 September 2018

An Algorithm for Least-Squares Estimation of Nonlinear Parameters

1 reference

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21 January 2018

Identifiers

10.1093/INFDIS/JIU565

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

1 reference

Europe PubMed Central

6 August 2017

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