(Q35165195)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24809353%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

title

Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737 (English)

1 reference

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17 March 2020

1

1 reference

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17 March 2020

Olivier Sperandio

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24809353%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Benoit Deprez

10

1 reference

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17 March 2020

11

Bruno O Villoutreix

1 reference

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17 March 2020

author name string

Virginie Pottiez

3

1 reference

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17 March 2020

Sophie Balzarin

4

1 reference

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17 March 2020

Adrien Herlédan

5

1 reference

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17 March 2020

Judith O Elkaïm

6

1 reference

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17 March 2020

Marie-Laure Fogeron

7

1 reference

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17 March 2020

Catherine Piveteau

8

1 reference

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17 March 2020

Sandrine Dassonneville

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24809353%20AND%20SRC:MED&resulttype=core&format=json

17 March 2020

Nathalie Bonnefoy

12

1 reference

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17 March 2020

Florence Leroux

13

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17 March 2020

publication date

8 May 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24809353%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biomolecular Screening

17 March 2020

published in

1 reference

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17 March 2020

volume

19

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17 March 2020

issue

7

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17 March 2020

page(s)

1035-1046

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24809353%20AND%20SRC:MED&resulttype=core&format=json

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

17 March 2020

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Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

21 January 2018

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An antiapoptotic BCL-2 family expression index predicts the response of chronic lymphocytic leukemia to ABT-737.

21 January 2018

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BCL2A1: the underdog in the BCL2 family

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NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

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Abnormal expression of apoptosis-related genes in haematological malignancies: overexpression of MYC is poor prognostic sign in mantle cell lymphoma.

21 January 2018

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High expression of bfl-1 contributes to the apoptosis resistant phenotype in B-cell chronic lymphocytic leukemia.

21 January 2018

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Upregulation of bfl-1 is a potential mechanism of chemoresistance in B-cell chronic lymphocytic leukaemia

21 January 2018

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Downregulation of Bfl-1 protein expression sensitizes malignant B cells to apoptosis

21 January 2018

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Characterization of peptide aptamers targeting Bfl-1 anti-apoptotic protein.

21 January 2018

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21 January 2018

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A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

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Thermodynamic studies for drug design and screening

21 January 2018

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

21 January 2018

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AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

21 January 2018

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Bax and Bak independently promote cytochrome C release from mitochondria

21 January 2018

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Completing the family portrait of the anti-apoptotic Bcl-2 proteins: crystal structure of human Bfl-1 in complex with Bim

21 January 2018

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21 January 2018

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A leap into the chemical space of protein-protein interaction inhibitors

21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

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Molecular properties that influence the oral bioavailability of drug candidates

21 January 2018

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Inhibition of Bfl-1 with N-aryl maleimides

21 January 2018

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High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1.

21 January 2018

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High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry

21 January 2018

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Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

21 January 2018

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