(Q35171016)

6 August 2017

Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase (English)

1 reference

6 August 2017

ataxia telangiectasia

1 reference

1 reference

Masaoki Kawasumi

1

1 reference

6 August 2017

Bianca Lemos

2

1 reference

6 August 2017

James E Bradner

3

1 reference

6 August 2017

Renee Thibodeau

4

1 reference

6 August 2017

Yong-son Kim

5

1 reference

6 August 2017

Miranda Schmidt

6

1 reference

6 August 2017

Erin Higgins

7

1 reference

6 August 2017

Sang-wahn Koo

8

1 reference

6 August 2017

Aimee Angle-Zahn

9

1 reference

6 August 2017

Adam Chen

10

1 reference

6 August 2017

Douglas Levine

11

1 reference

6 August 2017

Lynh Nguyen

12

1 reference

6 August 2017

Timothy P Heffernan

13

1 reference

6 August 2017

Isabel Longo

14

1 reference

6 August 2017

Anna Mandinova

15

1 reference

6 August 2017

Yao-Ping Lu

16

1 reference

6 August 2017

Allan H Conney

17

1 reference

6 August 2017

Paul Nghiem

18

1 reference

6 August 2017

language of work or name

English

0 references

publication date

15 August 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

1 reference

6 August 2017

108

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6 August 2017

33

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6 August 2017

13716-13721

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Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner

6 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

The DNA damage-binding protein XPC is a frequent target for inactivation in squamous cell carcinomas

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Epidemiologic evidence on coffee and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Cell cycle kinases as therapeutic targets for cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Modulation of cellular response to anticancer treatment by caffeine: inhibition of cell cycle checkpoints, DNA repair and more

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Tea consumption and basal cell and squamous cell skin cancer: results of a case-control study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

ATM promotes apoptosis and suppresses tumorigenesis in response to Myc.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

UVB-induced apoptosis drives clonal expansion during skin tumor development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

ATM-dependent CHK2 activation induced by anticancer agent, irofulven

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in mouse skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in UVB-induced skin tumors in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

DNA double-strand breaks: signaling, repair and the cancer connection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Alopecia universalis associated with a mutation in the human hairless gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Effects of tea, decaffeinated tea, and caffeine on UVB light-induced complete carcinogenesis in SKH-1 mice: demonstration of caffeine as a biologically important constituent of tea.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Protection from photodamage by topical application of caffeine after ultraviolet irradiation.

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Direct effects of caffeine and theophylline on p110 delta and other phosphoinositide 3-kinases. Differential effects on lipid kinase and protein kinase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

The hairless mouse in skin research.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3158235

Sunburn and p53 in the onset of skin cancer

27 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111378108

Daily coffee consumption and prevalence of nonmelanoma skin cancer in Caucasian women

21 January 2018

1 reference

12 December 2020

Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice

1 reference

12 December 2020

Tea intake and squamous cell carcinoma of the skin: influence of type of tea beverages

1 reference

12 December 2020

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

1 reference

12 December 2020

Characterization and histogenesis of tumors in the hairless mouse produced by low-dosage incremental ultraviolet radiation

1 reference

12 December 2020

Coffee drinking, mortality, and cancer incidence: results from a Norwegian prospective study

1 reference

12 December 2020

Mutations in ras oncogenes: rare events in ultraviolet B radiation-induced mouse skin tumorigenesis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1111378108

1 reference

release_7bqmqdprlfeqlpvjxzvuve4roy

6 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7bqmqdprlfeqlpvjxzvuve4roy

24 November 2022

mapped directly with Wikidata item

PMCID

3158235

1 reference

6 August 2017

1 reference