(Q33661151)

28 July 2017

Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. (English)

1 reference

28 July 2017

Yaroslava Ruzankina

1

1 reference

28 July 2017

David W Schoppy

2

1 reference

28 July 2017

Amma Asare

3

1 reference

28 July 2017

Carolyn E Clark

4

1 reference

28 July 2017

Robert H Vonderheide

5

1 reference

28 July 2017

Eric J Brown

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

30 August 2009

1 reference

28 July 2017

1 reference

28 July 2017

41

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28 July 2017

1144-1149

1 reference

28 July 2017

10

1 reference

https://scigraph.springernature.com/pub.10.1038/ng.441

28 July 2017

0 references

cites work

A two-step mechanism for stem cell activation during hair regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Senescence-messaging secretome: SMS-ing cellular stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Senescence of activated stellate cells limits liver fibrosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Cancer and ageing: convergent and divergent mechanisms

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

The ATR pathway: fine-tuning the fork

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Increased p53 activity does not accelerate telomere-driven ageing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Capturing and profiling adult hair follicle stem cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Modulation of mammalian life span by the short isoform of p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Cancer predisposition and hematopoietic failure in Rad50(S/S) mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

p53 mutant mice that display early ageing-associated phenotypes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

ATR and ATRIP: partners in checkpoint signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Analysis of ku80-mutant mice and cells with deficient levels of p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

ATR disruption leads to chromosomal fragmentation and early embryonic lethality

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

A mutation in mouse rad51 results in an early embryonic lethal that is suppressed by a mutation in p53

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

ATR and H2AX cooperate in maintaining genome stability under replication stress

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

p53 is essential for chemotherapy-induced hair loss

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Role of p53 in hematopoietic recovery after cytotoxic treatment.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

Delayed ageing through damage protection by the Arf/p53 pathway

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823374

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19718024

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNG.441

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NG.441

1 reference

28 July 2017

1 reference

28 July 2017

1 reference