(Q35179539)

7 August 2017

title

Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression (English)

1 reference

7 August 2017

T Lushnikova

1

1 reference

7 August 2017

A Bouska

2

1 reference

7 August 2017

J Odvody

3

1 reference

7 August 2017

W D Dupont

4

1 reference

7 August 2017

C M Eischen

5

1 reference

7 August 2017

language of work or name

English

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publication date

23 May 2011

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7 August 2017

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7 August 2017

volume

30

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7 August 2017

issue

46

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7 August 2017

page(s)

4622-4631

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2011.172

7 August 2017

exact match

0 references

cites work

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Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

13 July 2018

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13 July 2018

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Mdm2 affects genome stability independent of p53.

13 July 2018

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Mdm2 promotes genetic instability and transformation independent of p53.

13 July 2018

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Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations

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13 July 2018

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13 July 2018

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Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

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Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models

13 July 2018

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Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

13 July 2018

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MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy

13 July 2018

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SV40 T antigen interacts with Nbs1 to disrupt DNA replication control.

13 July 2018

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MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation

13 July 2018

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13 July 2018

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Polyploids require Bik1 for kinetochore-microtubule attachment

13 July 2018

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Pericentromeric organization at the fusion point of mouse Robertsonian translocation chromosomes.

13 July 2018

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Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

13 July 2018

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Frequency of spontaneous chromosome aberrations in mice: effects of age.

13 July 2018

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Genetic instabilities in human cancers

13 July 2018

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Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

13 July 2018

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p21(Waf1/Cip1) inhibition of cyclin E/Cdk2 activity prevents endoreduplication after mitotic spindle disruption

13 July 2018

1 reference

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DNA double-strand breaks, chromosomal rearrangements, and genomic instability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161162

Acceleration of chromosome aberrations in senescence-accelerated strains of mice.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161162

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161162

Cancer chromosomes in crisis

27 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FONC.2011.172

Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FONC.2011.172

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.172

1 reference

7 August 2017

1 reference

7 August 2017

1 reference