(Q81165896)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

author name string

P Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

T Lushnikova

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

J Odvody

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

T C Greiner

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

S N Jones

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

C M Eischen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

publication date

10 September 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

page(s)

1590-1598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828300%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

issue

11

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210788

6 January 2020

exact match

0 references

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The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

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7 January 2021

Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

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7 January 2021

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

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7 January 2021

mdm2 expression is induced by wild type p53 activity

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7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

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7 January 2021

Overexpression of MDM2, due to enhanced translation, results in inactivation of wild-type p53 in Burkitt's lymphoma cells.

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7 January 2021

A p53-dependent mouse spindle checkpoint

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7 January 2021

Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks

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7 January 2021

Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development

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7 January 2021

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

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7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

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7 January 2021

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

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7 January 2021

Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations

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7 January 2021

Proteomic analysis of mantle-cell lymphoma by protein microarray

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7 January 2021

ATM gene and lymphoid malignancies

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

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7 January 2021

The P53 pathway: what questions remain to be explored?

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7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

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7 January 2021

Modeling the therapeutic efficacy of p53 restoration in tumors

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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7 January 2021

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

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7 January 2021

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7 January 2021

Decreased Mdm2 expression inhibits tumor development induced by loss of ARF

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7 January 2021

Overexpression of the MDM2 oncogene in leukemia and lymphoma

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7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

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7 January 2021

Inactivation of the ARF-MDM-2-p53 pathway in sporadic Burkitt's lymphoma in children.

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7 January 2021

The p53-mdm-2 autoregulatory feedback loop

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7 January 2021