(Q82616832)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Decreased Mdm2 expression inhibits tumor development induced by loss of ARF (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

P Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

T C Greiner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

T Lushnikova

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

C M Eischen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

publication date

20 February 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

3708-3718

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16491126%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209411

17 January 2020

exact match

0 references

cites work

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

The loss of mdm2 induces p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Loss of one allele of ARF rescues Mdm2 haploinsufficiency effects on apoptosis and lymphoma development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Nuclear export is required for degradation of endogenous p53 by MDM2 and human papillomavirus E6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

"Super p53" mice exhibit enhanced DNA damage response, are tumor resistant and age normally

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

A cell cycle regulator potentially involved in genesis of many tumor types

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

ARF function does not require p53 stabilization or Mdm2 relocalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Increased gene dosage of Ink4a/Arf results in cancer resistance and normal aging.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

p53 mutant mice that display early ageing-associated phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Activation of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

p53-independent functions of the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209411

7 January 2021