(Q35227639)

7 August 2017

title

A glycine zipper motif mediates the formation of toxic β-amyloid oligomers in vitro and in vivo (English)

1 reference

7 August 2017

10

Michael A Silverman

1 reference

7 August 2017

Virginia Fonte

1

1 reference

7 August 2017

Vishantie Dostal

2

1 reference

7 August 2017

Christine M Roberts

3

1 reference

7 August 2017

Patrick Gonzales

4

1 reference

7 August 2017

Pascale N Lacor

5

1 reference

7 August 2017

Pauline T Velasco

6

1 reference

7 August 2017

Jordi Magrane

7

1 reference

7 August 2017

Natalie Dingwell

8

1 reference

7 August 2017

Emily Y Fan

9

1 reference

7 August 2017

Gretchen H Stein

11

1 reference

7 August 2017

Christopher D Link

12

1 reference

7 August 2017

language of work or name

1 reference

23 August 2011

1 reference

Molecular Neurodegeneration

7 August 2017

published in

1 reference

7 August 2017

volume

6

1 reference

7 August 2017

issue

1

1 reference

7 August 2017

page(s)

61

1 reference

https://scigraph.springernature.com/pub.10.1186/1750-1326-6-61

7 August 2017

exact match

0 references

cites work

Assaying β-amyloid toxicity using a transgenic C. elegans model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Role of amyloid-beta glycine 33 in oligomerization, toxicity, and neuronal plasticity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

The structure of a cytolytic alpha-helical toxin pore reveals its assembly mechanism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Destabilizing protein polymorphisms in the genetic background direct phenotypic expression of mutant SOD1 toxicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Computationally designed peptide inhibitors of protein-protein interactions in membranes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Solution state characterization of amyloid beta-derived diffusible ligands

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Mitochondrial dysfunction and Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Progressive disruption of cellular protein folding in models of polyglutamine diseases.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Transmembrane glycine zippers: physiological and pathological roles in membrane proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Globular amyloid beta-peptide oligomer - a homogenous and stable neuropathological protein in Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Gene expression analysis in a transgenic Caenorhabditis elegans Alzheimer's disease model

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

The threshold for polyglutamine-expansion protein aggregation and cellular toxicity is dynamic and influenced by aging in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Zn2+ interaction with Alzheimer amyloid beta protein calcium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Inhibition of the electrostatic interaction between beta-amyloid peptide and membranes prevents beta-amyloid-induced toxicity

27 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Oligomerization of endogenous and synthetic amyloid beta-protein at nanomolar levels in cell culture and stabilization of monomer by Congo red.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Amyloid-beta peptide (Abeta) neurotoxicity is modulated by the rate of peptide aggregation: Abeta dimers and trimers correlate with neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

The beta amyloid peptide can act as a modular aggregation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Heat shock protein 70 participates in the neuroprotective response to intracellularly expressed beta-amyloid in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

The plasticins: membrane adsorption, lipid disorders, and biological activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Structures of the glycine-rich diastereomeric peptides bombinin H2 and H4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Mitochondrial dysfunction, apoptotic cell death, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Activation of platelet alphaIIbbeta3 by an exogenous peptide corresponding to the transmembrane domain of alphaIIb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Monoclonal antibodies that target pathological assemblies of Abeta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

Genetic mechanisms of coffee extract protection in a Caenorhabditis elegans model of β-amyloid peptide toxicity

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Suppression of in vivo beta-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Decreased insulin-receptor signaling promotes the autophagic degradation of beta-amyloid peptide in C. elegans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178497

Intraneuronal -Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response

26 September 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-61

In vivo aggregation of beta-amyloid peptide variants

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21861874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure-function relationships of a novel bacterial toxin, hemolysin E. The role of alpha G

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21861874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structural malleability of plasticins: preorganized conformations in solution and relevance for antimicrobial activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21861874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1750-1326-6-61

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference