(Q35436367)

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Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409334%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy (English)

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23 February 2020

anti-retroviral agent

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23 February 2020

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23 February 2020

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23 February 2020

Gabriela Khoury

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23 February 2020

Paul Urquhart Cameron

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23 February 2020

Sharon R. Lewin

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23 February 2020

Steven L Wesselingh

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Steve Wesselingh

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23 February 2020

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Paula Ellenberg

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23 February 2020

Wan-Jung Cheng

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23 February 2020

Talia M Mota

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23 February 2020

Paul R Gorry

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23 February 2020

Melissa J Churchill

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23 February 2020

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19 November 2014

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23 February 2020

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409334%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

9

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23 February 2020

11

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23 February 2020

e113341

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23 February 2020

copyright license

Creative Commons Attribution 4.0 International

19 November 2014

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April 2022 Public Data File from Crossref

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0 references

Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial

1 reference

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27 July 2018

Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy

1 reference

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27 July 2018

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Entinostat is a histone deacetylase inhibitor selective for class 1 histone deacetylases and activates HIV production from latently infected primary T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

The effect of N-acetylation and N-methylation of lysine residue of Tat peptide on its interaction with HIV-1 TAR RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Efficient replication of Epstein-Barr virus-derived plasmids requires tethering by EBNA1 to host chromosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Unique characteristics of histone deacetylase inhibitors in reactivation of latent HIV-1 in Bcl-2-transduced primary resting CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Systematic Analysis of the Functions of Lysine Acetylation in the Regulation of Tat Activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Comparison of HDAC inhibitors in clinical development: effect on HIV production in latently infected cells and T-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Molecular mechanisms of metabolic reprogramming in proliferating cells: implications for T-cell-mediated immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

HDAC inhibitors in HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Combinatorial latency reactivation for HIV-1 subtypes and variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Expression of latent human immunodeficiency type 1 is induced by novel and selective histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

"Shock and kill" effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Anticancer activities of histone deacetylase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Lsh is involved in de novo methylation of DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

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Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

1 reference

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Replication and episomal maintenance of Epstein-Barr virus-based vectors in mouse embryonal fibroblasts enable synthetic lethality screens

1 reference

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HIV-1 tat transcriptional activity is regulated by acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

27 July 2018

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

1 reference

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Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.

1 reference

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Activation of a heterologous promoter by human immunodeficiency virus type 1 Tat requires Sp1 and is distinct from the mode of activation by acidic transcriptional activators.

1 reference

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Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.

1 reference

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Establishment of a line of human fetal glial cells that supports JC virus multiplication

1 reference

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Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone

1 reference

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Linker-scanning mutational analysis of the transcriptional activity of the human immunodeficiency virus type 1 long terminal repeat

1 reference

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Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat

1 reference

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27 July 2018

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113341

21 January 2018

Both CD31(+) and CD31⁻ naive CD4(+) T cells are persistent HIV type 1-infected reservoirs in individuals receiving antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113341

21 January 2018

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113341

21 January 2018

Histone deacetylase inhibitors (HDACis) that release the positive transcription elongation factor b (P-TEFb) from its inhibitory complex also activate HIV transcription

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113341

21 January 2018

Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0113341

21 January 2018

Short communication: SAHA (vorinostat) induces CDK9 Thr-186 (T-loop) phosphorylation in resting CD4+ T cells: implications for reactivation of latent HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

26 September 2018

Reduced basal transcriptional activity of central nervous system-derived HIV type 1 long terminal repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4237424

26 September 2018

Kick-sTARting HIV-1 transcription elongation by 7SK snRNP deporTATion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25409334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25409334

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0113341

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409334%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2014PLoSO...9k3341L

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409334%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25409334%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

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