(Q35492403)

English

Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

retracted paper

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Retraction Watch

29 December 2023

https://doi.org/10.1111/jnc.15832

Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells (English)

1 reference

Europe PubMed Central

8 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Jaya Prasanthi Rantham Prabhakara

1

1 reference

Europe PubMed Central

8 August 2017

Gwen Feist

2

1 reference

Europe PubMed Central

8 August 2017

Sarah Thomasson

3

1 reference

Europe PubMed Central

8 August 2017

Alex Thompson

4

1 reference

Europe PubMed Central

8 August 2017

Eric Schommer

5

1 reference

Europe PubMed Central

8 August 2017

Othman Ghribi

6

1 reference

Europe PubMed Central

8 August 2017

language of work or name

0 references

publication date

5 November 2008

1 reference

Europe PubMed Central

8 August 2017

Journal of Neurochemistry

1 reference

Europe PubMed Central

8 August 2017

107

1 reference

Europe PubMed Central

8 August 2017

6

1 reference

Europe PubMed Central

8 August 2017

1722-1729

1 reference

Europe PubMed Central

8 August 2017

Oxysterols as biomarkers in neurodegenerative diseases

1 reference

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Lipid pathway alterations in Parkinson's disease primary visual cortex

1 reference

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Regulation of alpha-synuclein expression by liver X receptor ligands in vitro

1 reference

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Different patterns of oxidized lipid products in plasma and urine of dengue fever, stroke, and Parkinson's disease patients: cautions in the use of biomarkers of oxidative stress.

1 reference

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Dietary fats, cholesterol and iron as risk factors for Parkinson's disease

1 reference

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Total cholesterol and the risk of Parkinson disease

1 reference

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Liver X receptor beta (LXRbeta): a link between beta-sitosterol and amyotrophic lateral sclerosis-Parkinson's dementia

1 reference

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27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen

1 reference

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12 July 2018

27-hydroxycholesterol is an endogenous selective estrogen receptor modulator

1 reference

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12 July 2018

Estrogen receptor beta in the brain: from form to function

1 reference

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12 July 2018

Effect of alpha-synuclein on the promoter activity of tyrosine hydroxylase gene

1 reference

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12 July 2018

Distribution and localization patterns of estrogen receptor-beta and insulin-like growth factor-1 receptors in neurons and glial cells of the female rat substantia nigra: localization of ERbeta and IGF-1R in substantia nigra

1 reference

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12 July 2018

The nuclear receptor LXR is a glucose sensor

1 reference

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12 July 2018

Nuclear localization of liver X receptor alpha and beta is differentially regulated

1 reference

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12 July 2018

Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity

1 reference

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12 July 2018

Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Transcriptional regulation of tyrosine hydroxylase by estrogen: opposite effects with estrogen receptors alpha and beta and interactions with cyclic AMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Inhibition of tyrosine hydroxylase expression in alpha-synuclein-transfected dopaminergic neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Tyrosine hydroxylase transcription depends primarily on cAMP response element activity, regardless of the type of inducing stimulus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Comparison of kindreds with parkinsonism and alpha-synuclein genomic multiplications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

alpha-Synuclein locus triplication causes Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Interactions between Egr1 and AP1 factors in regulation of tyrosine hydroxylase transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Novel roles of liver X receptors exposed by gene expression profiling in liver and adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Liver X receptors in the central nervous system: from lipid homeostasis to neuronal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Oxysterols in human circulation: which role do they have?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

A role for alpha-synuclein in the regulation of dopamine biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

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Estradiol stimulates gene expression of norepinephrine biosynthetic enzymes in rat locus coeruleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Autoregulation of the human liver X receptor alpha promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

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Increased anxiety and synaptic plasticity in estrogen receptor beta -deficient mice.

1 reference

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Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Liver X receptor (LXR) regulation of the LXRalpha gene in human macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

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Auto-oxidized cholesterol sulfates are antagonistic ligands of liver X receptors: implications for the development and treatment of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

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LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Role of LXRs in control of lipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

12 July 2018

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

1 reference

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12 July 2018

Characterisation of isolated alpha-synuclein filaments from substantia nigra of Parkinson's disease brain

1 reference

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12 July 2018

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

1 reference

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12 July 2018

Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

1 reference

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12 July 2018

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

1 reference

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12 July 2018

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

1 reference

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12 July 2018

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

1 reference

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12 July 2018

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

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Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions.

1 reference

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Nuclear receptor coregulators: cellular and molecular biology

1 reference

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12 July 2018

Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta

1 reference

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12 July 2018

Expression and neuropeptidergic characterization of estrogen receptors (ERalpha and ERbeta) throughout the rat brain: anatomical evidence of distinct roles of each subtype.

1 reference

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12 July 2018

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

1 reference

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12 July 2018

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

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12 July 2018

The orphan nuclear receptor LXRalpha is positively and negatively regulated by distinct products of mevalonate metabolism

1 reference

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12 July 2018

Alpha-synuclein in Lewy bodies

1 reference

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12 July 2018

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

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12 July 2018

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

1 reference

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12 July 2018

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

1 reference

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12 July 2018

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

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Steroid hormone receptors: many actors in search of a plot

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The nuclear receptor superfamily: the second decade

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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12 July 2018

Both the basal and inducible transcription of the tyrosine hydroxylase gene are dependent upon a cAMP response element.

1 reference

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12 July 2018

OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor

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12 July 2018

LXR, a nuclear receptor that defines a distinct retinoid response pathway

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12 July 2018

Effect of dibutyryl cyclic adenosine monophosphate on 14C-dopamine biosynthesis in rat brain striatal slices.

1 reference

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12 July 2018

Phosphorylation of tyrosine hydroxylase in situ at serine 8, 19, 31, and 40

1 reference

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12 July 2018

Tyrosine hydroxylase in rat brain dopaminergic nerve terminals. Multiple-site phosphorylation in vivo and in synaptosomes

1 reference

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12 July 2018

Changes in tyrosine hydroxylase mRNA levels in medullary A1 and A2 neurons and locus coeruleus following castration and estrogen replacement in rats

1 reference

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12 July 2018

Sequences that direct rat tyrosine hydroxylase gene expression

1 reference

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12 July 2018

Regulated expression of the tyrosine hydroxylase gene by membrane depolarization. Identification of the responsive element and possible second messengers

1 reference

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12 July 2018

Evidence for involvement of protein kinase in the activation by adenosine 3':5'-monophosphate of brain tyrosine 3-monooxygenase

1 reference

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12 July 2018

Oxidative damage in Parkinson disease: Measurement using accurate biomarkers.

1 reference

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26 September 2018

Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells

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26 September 2018

Reduced risk factors for vascular disorders in Parkinson disease patients: a case-control study.

1 reference

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26 September 2018

6-Hydroxydopamine but not 1-methyl-4-phenylpyridinium abolishes alpha-synuclein anti-apoptotic phenotype by inhibiting its proteasomal degradation and by promoting its aggregation

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26 September 2018

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

1 reference

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26 September 2018

Response of tyrosine hydroxylase and GTP cyclohydrolase I gene expression to estrogen in brain catecholaminergic regions varies with mode of administration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Oestradiol-dependent and -independent modulation of tyrosine hydroxylase mRNA levels in subpopulations of A1 and A2 neurones with oestrogen receptor (ER)alpha and ER beta gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Sex differences in the regulation of tyrosine hydroxylase gene transcription by estrogen in the locus coeruleus of TH9-LacZ transgenic mice

1 reference

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26 September 2018

Accumulation of foam cells in liver X receptor-deficient mice

1 reference

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26 September 2018

Estradiol protects dopaminergic neurons in a MPP+Parkinson's disease model.

1 reference

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26 September 2018

Dopamine-dependent neurotoxicity of alpha-synuclein: a mechanism for selective neurodegeneration in Parkinson disease

1 reference

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26 September 2018

Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Neuroprotective properties of 17beta-estradiol, progesterone, and raloxifene in MPTP C57Bl/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Stereospecific prevention by 17beta-estradiol of MPTP-induced dopamine depletion in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Structural characterisation of the mouse nuclear oxysterol receptor genes LXRalpha and LXRbeta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Estradiol protects mesencephalic dopaminergic neurons from oxidative stress-induced neuronal death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Localization and ontogeny of the orphan receptor OR-1 in the rat brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Estradiol increases tyrosine hydroxylase activity of the A15 nucleus dopaminergic neurons during long days in the ewe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

26 September 2018

Serum Cholesterol Levels and the Risk of Parkinson's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3205449

7 December 2018

The LXRs: a new class of oxysterol receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19014385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ovarian steroids and raloxifene prevent MPTP-induced dopamine depletion in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19014385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neurotoxic effect of 24-hydroxycholesterol on SH-SY5Y human neuroblastoma cells.

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

In vitro cytotoxicity assays: comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Oxysterols and Alzheimer's disease.

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Alpha-synuclein aggregation alters tyrosine hydroxylase phosphorylation and immunoreactivity: lessons from viral transduction of knockout mice

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Brain cholesterol: long secret life behind a barrier.

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Acute effects of a bicyclophosphate neuroconvulsant on monoamine neurotransmitter and metabolite levels in the rat brain.

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Intricate regulation of tyrosine hydroxylase activity and gene expression

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Adult nutrient intake as a risk factor for Parkinson's disease

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Epidemiology versus genetics in Parkinson's disease: progress in resolving an age-old debate

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Dietary fatty acids and the risk of Parkinson disease: the Rotterdam study

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Cytotoxicity of 7-ketocholesterol toward cultured rat hepatocytes and the effect of vitamin E

1 reference

https://opencitations.net/index/api/v1/references/10.1111/J.1471-4159.2008.05736.X

30 December 2023

Identifiers

10.1111/J.1471-4159.2008.05736.X

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

ResearchGate publication ID

0 references

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