(Q35529960)

25902443

8 August 2017

title

Direct Detection of α-Synuclein Dimerization Dynamics: Single-Molecule Fluorescence Analysis (English)

1 reference

8 August 2017

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Zhengjian Lv

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Alexey V Krasnoslobodtsev

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Yuliang Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Daniel Ysselstein

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jean-Christophe Rochet

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Yuri L Lyubchenko

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

1 April 2015

1 reference

25902443

8 August 2017

number of pages

10

1 reference

based on heuristic

inferred from page(s)

published in

Biophysical Journal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

2038-2047

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

Diverse metastable structures formed by small oligomers of α-synuclein probed by force spectroscopy

10 June 2020

cites work

1 reference

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Single-Molecule Studies of Intrinsically Disordered Proteins

27 July 2018

1 reference

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Nanoprobing of misfolding and interactions of amyloid β 42 protein

27 July 2018

1 reference

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Defining the native state of α-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Ultra-stable organic fluorophores for single-molecule research

27 July 2018

1 reference

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Abeta, oxidative stress in Alzheimer disease: evidence based on proteomics studies

27 July 2018

1 reference

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Mechanism of amyloid β-protein dimerization determined using single-molecule AFM force spectroscopy

27 July 2018

1 reference

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α-Synuclein misfolding assessed with single molecule AFM force spectroscopy: effect of pathogenic mutations

27 July 2018

1 reference

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The function of α-synuclein

27 July 2018

1 reference

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Properties of native brain α-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

The remarkable conformational plasticity of alpha-synuclein: blessing or curse?

27 July 2018

1 reference

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On-surface aggregation of α-synuclein at nanomolar concentrations results in two distinct growth mechanisms

27 July 2018

1 reference

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Real-time single-molecule co-immunoprecipitation analyses reveal cancer-specific Ras signalling dynamics.

27 July 2018

1 reference

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Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Aggregation of islet amyloid polypeptide: from physical chemistry to cell biology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Understanding protein aggregation from the view of monomer dynamics

27 July 2018

1 reference

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Common features at the start of the neurodegeneration cascade

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Effect of spermidine on misfolding and interactions of alpha-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Direct observation of the interconversion of normal and toxic forms of α-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Effect of electrostatics on aggregation of prion protein Sup35 peptide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Aggregation of α-synuclein is kinetically controlled by intramolecular diffusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Cyanine fluorophore derivatives with enhanced photostability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Α-synuclein misfolding and Parkinson's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Probing the efficacy of peptide-based inhibitors against acid- and zinc-promoted oligomerization of amyloid-β peptide via single-oligomer spectroscopy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Single-molecule atomic force microscopy force spectroscopy study of Aβ-40 interactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

α-Synuclein-induced tubule formation in lipid bilayers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Toward a molecular theory of early and late events in monomer to amyloid fibril formation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Single molecule characterization of α-synuclein in aggregation-prone states

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Nanoimaging for protein misfolding diseases

27 July 2018

1 reference

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Adsorption of alpha-synuclein on lipid bilayers: modulating the structure and stability of protein assemblies

27 July 2018

1 reference

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Molecular mechanism underlying RAG1/RAG2 synaptic complex formation

27 July 2018

1 reference

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Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

alpha-Synuclein misfolding: single molecule AFM force spectroscopy study

27 July 2018

1 reference

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A practical guide to single-molecule FRET

27 July 2018

1 reference

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Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Conformational equilibria in monomeric alpha-synuclein at the single-molecule level

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Lifetime measurements reveal kinetic differences between homophilic cadherin bonds

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

The E46K mutation in alpha-synuclein increases amyloid fibril formation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Molecular Pathways of Neurodegeneration in Parkinson's Disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Oxidative dimer formation is the critical rate-limiting step for Parkinson's disease alpha-synuclein fibrillogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

The effect of force on thermodynamics and kinetics of single molecule reactions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human alpha-synuclein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Co-existence of two different α-synuclein oligomers with different core structures determined by hydrogen/deuterium exchange mass spectrometry.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Molecular mechanism of misfolding and aggregation of Aβ(13-23).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Covalent α-synuclein dimers: chemico-physical and aggregation properties

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

The many faces of α-synuclein: from structure and toxicity to therapeutic target

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

100 years of Lewy pathology

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Nanoprobing of the effect of Cu(2+) cations on misfolding, interaction and aggregation of amyloid β peptide

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Mica functionalization for imaging of DNA and protein-DNA complexes with atomic force microscopy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

On the Mechanisms of Cyanine Fluorophore Photostabilization.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

A model of nitric oxide induced α-synuclein misfolding in Parkinson's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Pathogenic mutations shift the equilibria of alpha-synuclein single molecules towards structured conformers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

The fold of alpha-synuclein fibrils

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Dynamics of synaptic SfiI-DNA complex: single-molecule fluorescence analysis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4407253

Nanoprobing of α-synuclein misfolding and aggregation with atomic force microscopy

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25902443

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BPJ.2015.03.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

25902443

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25902443%20AND%20SRC:MED&resulttype=core&format=json