(Q35552889)

English

HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial

scientific article published on 29 April 2015

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scholarly article

1 reference

Europe PubMed Central

8 August 2017

HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial (English)

1 reference

Europe PubMed Central

8 August 2017

phase II clinical trial

0 references

Giovanni Paniccia

object named as

Giovanni Paniccia

16

0 references

object named as

Chiara Orlandi

13

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Stefania Bellino

object named as

Stefania Bellino

5

0 references

Orietta Picconi

object named as

Orietta Picconi

8

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Cecilia Sgadari

object named as

Cecilia Sgadari

9

0 references

Fabrizio Ensoli

object named as

Fabrizio Ensoli

1

0 references

object named as

Paolo Monini

28

0 references

Gioacchino Angarano

object named as

Gioacchino Angarano

22

0 references

object named as

Massimo Galli

24

0 references

object named as

Barbara Ensoli

31

0 references

Adriano Lazzarin

object named as

Adriano Lazzarin

18

0 references

21

object named as

Andrea Gori

1 reference

Europe PubMed Central

8 August 2017

29

object named as

Mauro Magnani

1 reference

Europe PubMed Central

8 August 2017

Anna Casabianca

3

object named as

Anna Casabianca

1 reference

Europe PubMed Central

8 August 2017

author name string

Aurelio Cafaro

2

1 reference

Europe PubMed Central

8 August 2017

Antonella Tripiciano

4

1 reference

Europe PubMed Central

8 August 2017

Olimpia Longo

6

1 reference

Europe PubMed Central

8 August 2017

Vittorio Francavilla

7

1 reference

Europe PubMed Central

8 August 2017

Sonia Moretti

10

1 reference

Europe PubMed Central

8 August 2017

Maria R Pavone Cossut

11

1 reference

Europe PubMed Central

8 August 2017

Angela Arancio

12

1 reference

Europe PubMed Central

8 August 2017

Leonardo Sernicola

14

1 reference

Europe PubMed Central

8 August 2017

Maria T Maggiorella

15

1 reference

Europe PubMed Central

8 August 2017

Cristina Mussini

17

1 reference

Europe PubMed Central

8 August 2017

Laura Sighinolfi

19

1 reference

Europe PubMed Central

8 August 2017

Guido Palamara

20

1 reference

Europe PubMed Central

8 August 2017

Massimo Di Pietro

23

1 reference

Europe PubMed Central

8 August 2017

Vito S Mercurio

25

1 reference

Europe PubMed Central

8 August 2017

Francesco Castelli

26

1 reference

Europe PubMed Central

8 August 2017

Giovanni Di Perri

27

1 reference

Europe PubMed Central

8 August 2017

Enrico Garaci

30

1 reference

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8 August 2017

publication date

29 April 2015

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Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

12

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Europe PubMed Central

8 August 2017

33

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Europe PubMed Central

8 August 2017

copyright license

Creative Commons Attribution 4.0 International

29 April 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1186/s12977-015-0151-y

0 references

HIV reservoir dynamics in the face of highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Eradicating HIV-1 infection: seeking to clear a persistent pathogen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

A real time PCR platform for the simultaneous quantification of total and extrachromosomal HIV DNA forms in blood of HIV-1 infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Challenges in HIV Vaccine Research for Treatment and Prevention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4+ T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV-1 Tat affects the programming and functionality of human CD8⁺ T cells by modulating the expression of T-box transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality

1 reference

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Emerging therapies for food allergy.

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27 July 2018

Central memory CD4 T cells are associated with incomplete restoration of the CD4 T cell pool after treatment-induced long-term undetectable HIV viraemia

1 reference

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27 July 2018

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

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27 July 2018

Novel biopanning strategy to identify epitopes associated with vaccine protection

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27 July 2018

B-cell subset alterations and correlated factors in HIV-1 infection

1 reference

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27 July 2018

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies

1 reference

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Novel cell and gene therapies for HIV.

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27 July 2018

The T-cell response to HIV.

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Innate immune control of HIV.

1 reference

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27 July 2018

Therapeutic vaccines against HIV infection

1 reference

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27 July 2018

Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation

1 reference

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27 July 2018

HIV reservoirs in vivo and new strategies for possible eradication of HIV from the reservoir sites

1 reference

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27 July 2018

Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Broadly cross-neutralizing antibodies in HIV-1 patients with undetectable viremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV reservoirs: the new frontier.

1 reference

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27 July 2018

Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Generation of effector CD8+ T cells and their conversion to memory T cells

1 reference

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27 July 2018

Antiretroviral therapy and management of HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Impact of viral dose and major histocompatibility complex class IB haplotype on viral outcome in mauritian cynomolgus monkeys vaccinated with Tat upon challenge with simian/human immunodeficiency virus SHIV89.6P

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

The potential of CD4 T-cell memory

1 reference

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27 July 2018

Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Targeting early infection to prevent HIV-1 mucosal transmission.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

The preventive phase I trial with the HIV-1 Tat-based vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Defective human immunodeficiency virus-specific CD8+ T-cell polyfunctionality, proliferation, and cytotoxicity are not restored by antiretroviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Rapid desensitization for hypersensitivity reactions to medications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV interactions with monocytes and dendritic cells: viral latency and reservoirs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Simplification strategies to reduce antiretroviral drug exposure: progress and prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Incomplete peripheral CD4+ cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV infection, antiretroviral treatment, ageing, and non-AIDS related morbidity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Immune activation and inflammation in HIV-1 infection: causes and consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Antigen sparing and cross-reactive immunity with an adjuvanted rH5N1 prototype pandemic influenza vaccine: a randomised controlled trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Proteomic and biochemical analysis of purified human immunodeficiency virus type 1 produced from infected monocyte-derived macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

The evolutionary dynamics of human endogenous retroviral families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV-1 tat protein modulates the generation of cytotoxic T cell epitopes by modifying proteasome composition and enzymatic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Transmission, acute HIV-1 infection and the quest for strategies to prevent infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Switching effective antiretroviral therapy: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Quantitation of human immunodeficiency virus type 1 DNA forms with the second template switch in peripheral blood cells predicts disease progression independently of plasma RNA load

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Decay kinetics of human immunodeficiency virus-specific CD8+ T cells in peripheral blood after initiation of highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Tat protein induces self-perpetuating permissivity for productive HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Effect of antibody to HIV-1 Tat protein on viral replication in vitro and progression of HIV-1 disease in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

27 July 2018

Surface-bound Tat inhibits antigen-specific CD8+ T-cell activation in an integrin-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Immune activation and HIV persistence: implications for curative approaches to HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

The CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Antiretroviral therapy does not block the secretion of the human immunodeficiency virus tat protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Pathologic natural killer cell subset redistribution in HIV-1 infection: new insights in pathophysiology and clinical outcomes.

1 reference

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26 September 2018

Immobilized HIV-1 Tat protein promotes gene transfer via a transactivation-independent mechanism which requires binding of Tat to viral particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Phase I therapeutic trial of the HIV-1 Tat protein and long term follow-up.

1 reference

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26 September 2018

Incomplete reconstitution of T cell subsets on combination antiretroviral therapy in the AIDS Clinical Trials Group protocol 384.

1 reference

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26 September 2018

Cellular reservoirs of HIV-1 and their role in viral persistence

1 reference

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26 September 2018

HIV-1 residual viremia and proviral DNA in patients with suppressed plasma viral load (<400 HIV-RNA cp/ml) during different antiretroviral regimens

1 reference

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26 September 2018

The presence of anti-Tat antibodies is predictive of long-term nonprogression to AIDS or severe immunodeficiency: findings in a cohort of HIV-1 seroconverters

1 reference

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26 September 2018

Sequence conservation and antibody cross-recognition of clade B human immunodeficiency virus (HIV) type 1 Tat protein in HIV-1-infected Italians, Ugandans, and South Africans

1 reference

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26 September 2018

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

1 reference

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26 September 2018

Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4414440

26 September 2018

Selective transcription and modulation of resting T cell activity by preintegrated HIV DNA.

1 reference

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26 September 2018

Impact of HIV Type 1 DNA Levels on Spontaneous Disease Progression: A Meta-Analysis

1 reference

https://api.crossref.org/works/10.1186%2FS12977-015-0151-Y

21 January 2018

The therapeutic phase I trial of the recombinant native HIV-1 Tat protein

1 reference

https://api.crossref.org/works/10.1186%2FS12977-015-0151-Y

21 January 2018

Control of SHIV-89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of antibody response to recombinant HIV-1 gene-encoded products nef, rev, tat, and protease in predicting development of AIDS in HIV-1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose sparing with intradermal injection of influenza vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non-progression status in HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Tat protein broadens T cell responses directed to the HIV-1 antigens Gag and Env: Implications for the design of new vaccination strategies against AIDS

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune Hyperactivation of HIV-1-Infected T Cells Mediated by Tat and the CD28 Pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/25924841

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S12977-015-0151-Y

1 reference

Europe PubMed Central

8 August 2017

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0 references

1 reference

Europe PubMed Central

8 August 2017

1 reference

Europe PubMed Central

8 August 2017

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