(Q35558027)

English

Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition

scientific article published on 10 June 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

2 references

30 January 2021

13 January 2024

Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

2 references

30 January 2021

13 January 2024

breast neoplasm

2 references

30 January 2021

13 January 2024

neoplastic stem cells

1 reference

12 October 2019

signal transduction

1 reference

26 August 2020

epithelial to mesenchymal transition

1 reference

30 January 2021

1 reference

based on heuristic

inferred from title

author name string

Naoko Takebe

1

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Ronald Q Warren

2

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

S Percy Ivy

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

10 June 2011

8 references

Europe PubMed Central

PubMed publication ID

8 August 2017

13 March 2019

3 April 2019

17 June 2019

12 October 2019

26 August 2020

30 January 2021

13 January 2024

Breast Cancer Research

7 references

Europe PubMed Central

PubMed publication ID

8 August 2017

13 March 2019

3 April 2019

17 June 2019

12 October 2019

26 August 2020

13 January 2024

13

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

211

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

https://scigraph.springernature.com/pub.10.1186/bcr2876

0 references

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

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Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

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Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

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12 July 2018

A Wnt-ow of opportunity: targeting the Wnt/beta-catenin pathway in breast cancer

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Cancer stem cells and self-renewal.

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12 July 2018

The difficulty of targeting cancer stem cell niches

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Targeting Hedgehog--a cancer stem cell pathway

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Targeting Notch to target cancer stem cells.

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12 July 2018

Controversies in cancer stem cells: targeting embryonic signaling pathways

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The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells

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12 July 2018

Stem cells in the human breast

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LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy

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ABCG2: a potential marker of stem cells and novel target in stem cell and cancer therapy

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Survival and self-renewing capacity of breast cancer initiating cells during fractionated radiation treatment

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12 July 2018

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

1 reference

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12 July 2018

The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

1 reference

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12 July 2018

MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis

1 reference

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12 July 2018

Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer

1 reference

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12 July 2018

Heterogeneity in cancer: cancer stem cells versus clonal evolution

1 reference

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12 July 2018

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

1 reference

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12 July 2018

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

1 reference

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12 July 2018

Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction - a model for cross-modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Tumor-initiating cells of HER2-positive carcinoma cell lines express the highest oncoprotein levels and are sensitive to trastuzumab

1 reference

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12 July 2018

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Association of reactive oxygen species levels and radioresistance in cancer stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

MicroRNAs: target recognition and regulatory functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Cancer and the tumor microenvironment: a review of an essential relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Transcriptional regulation of cell polarity in EMT and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Signaling cross-talk between TGF-beta/BMP and other pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Wnt1 overexpression promotes tumour progression in non-small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Generation of breast cancer stem cells through epithelial-mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

TGFbeta in Cancer

1 reference

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12 July 2018

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Mechanisms of malignant progression

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Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Mechanisms of Disease: cancer stem cells--targeting the evil twin

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12 July 2018

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Brca1 breast tumors contain distinct CD44+/CD24- and CD133+ cells with cancer stem cell characteristics

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12 July 2018

BRCA1 regulates human mammary stem/progenitor cell fate

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Endogenous human microRNAs that suppress breast cancer metastasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

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12 July 2018

Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

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12 July 2018

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers

1 reference

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12 July 2018

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3218933

12 July 2018

Common critical pathways in embryogenesis and cancer

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12 July 2018

Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: implications for progression of ErbB2-overexpressing tumors

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12 July 2018

Stem cells and their niches

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12 July 2018

E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines.

1 reference

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12 July 2018

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

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12 July 2018

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

1 reference

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12 July 2018

Wnt signaling in disease and in development

1 reference

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12 July 2018

Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

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12 July 2018

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

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12 July 2018

Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition

1 reference

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12 July 2018

E-cadherin expression in primary carcinomas of the breast and its distant metastases

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12 July 2018

From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression

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12 July 2018

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

1 reference

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12 July 2018

Regulation of tight junctions during the epithelium-mesenchyme transition: direct repression of the gene expression of claudins/occludin by Snail

1 reference

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12 July 2018

Prospective identification of tumorigenic breast cancer cells

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12 July 2018

Comparative gene expression profile analysis of GLI and c-MYC in an epithelial model of malignant transformation.

1 reference

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12 July 2018

Epithelial-mesenchymal transitions in tumour progression

1 reference

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12 July 2018

The functional and clinical roles of osteopontin in cancer and metastasis.

1 reference

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12 July 2018

Cancer susceptibility and the functions of BRCA1 and BRCA2

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12 July 2018

Hedgehog signaling in animal development: paradigms and principles

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12 July 2018

Beta-catenin, a novel prognostic marker for breast cancer: its roles in cyclin D1 expression and cancer progression

1 reference

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12 July 2018

Mapping sonic hedgehog-receptor interactions by steric interference

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12 July 2018

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

1 reference

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12 July 2018

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

1 reference

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12 July 2018

Notch signaling: cell fate control and signal integration in development

1 reference

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12 July 2018

Sonic hedgehog signaling by the patched-smoothened receptor complex

1 reference

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12 July 2018

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

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12 July 2018

Polycombing the genome: PcG, trxG, and chromatin silencing

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12 July 2018

Regulation of the ERBB-2 promoter by RBPJkappa and NOTCH.

1 reference

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12 July 2018

An overview of epithelio-mesenchymal transformation

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12 July 2018

Dormancy of mammary carcinoma after mastectomy.

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https://api.crossref.org/works/10.1186%2FBCR2876

21 January 2018

Mutations of the human E-cadherin (CDH1) gene.

1 reference

https://api.crossref.org/works/10.1186%2FBCR2876

21 January 2018

Invasive potential induced under long-term oxidative stress in mammary epithelial cells

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21 January 2018

MicroRNAs--the micro steering wheel of tumour metastases

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https://pubmed.ncbi.nlm.nih.gov/21672282

12 December 2020

based on heuristic

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E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21672282

12 December 2020

based on heuristic

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The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21672282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of notch-1 inhibits invasion by inactivation of nuclear factor-kappaB, vascular endothelial growth factor, and matrix metalloproteinase-9 in pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21672282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/BCR2876

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 August 2017

ResearchGate publication ID

0 references

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