(Q35568467)

8 August 2017

title

Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence (English)

1 reference

8 August 2017

13

George Q Daley

0 references

Leonard I. Zon

9

object named as

Leonard I Zon

1 reference

8 August 2017

1

Peter Geon Kim

1 reference

8 August 2017

Haruko Nakano

2

1 reference

8 August 2017

Partha P Das

3

1 reference

8 August 2017

Michael J Chen

4

1 reference

8 August 2017

R Grant Rowe

5

1 reference

8 August 2017

Stephanie S Chou

6

1 reference

8 August 2017

Samantha J Ross

7

1 reference

8 August 2017

Kathleen M Sakamoto

8

1 reference

8 August 2017

Thorsten M Schlaeger

10

1 reference

8 August 2017

Stuart H Orkin

11

1 reference

8 August 2017

Atsushi Nakano

12

1 reference

8 August 2017

language of work or name

English

0 references

publication date

13 April 2015

1 reference

Journal of Experimental Medicine

8 August 2017

published in

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8 August 2017

volume

212

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8 August 2017

issue

5

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8 August 2017

page(s)

633-648

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describes a project that uses

8 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4419355/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Effect of developmental stage of HSC and recipient on transplant outcomes

27 July 2018

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27 July 2018

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Signaling axis involving Hedgehog, Notch, and Scl promotes the embryonic endothelial-to-hematopoietic transition

27 July 2018

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T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures.

27 July 2018

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The transcriptional landscape of hematopoietic stem cell ontogeny

27 July 2018

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Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis

27 July 2018

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ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

27 July 2018

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Hematopoietic stem cell development requires transient Wnt/β-catenin activity

27 July 2018

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27 July 2018

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Role of shear-stress-induced VEGF expression in endothelial cell survival

27 July 2018

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PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction

27 July 2018

1 reference

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Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

27 July 2018

1 reference

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Prostaglandin E2 enhances human cord blood stem cell xenotransplants and shows long-term safety in preclinical nonhuman primate transplant models.

27 July 2018

1 reference

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MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Histone H3K27ac separates active from poised enhancers and predicts developmental state

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

ENCODE whole-genome data in the UCSC genome browser (2011 update)

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Dynamic combinatorial interactions of RUNX1 and cooperating partners regulates megakaryocytic differentiation in cell line models

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Haematopoietic stem cells derive directly from aortic endothelium during development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

27 July 2018

1 reference

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Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Hematopoietic stem cell development is dependent on blood flow.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Biomechanical forces promote embryonic haematopoiesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

BMP type I receptor inhibition reduces heterotopic [corrected] ossification

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Model-based analysis of ChIP-Seq (MACS)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Bone morphogenetic protein 4 modulates c-Kit expression and differentiation potential in murine embryonic aorta-gonad-mesonephros haematopoiesis in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

The landscape of histone modifications across 1% of the human genome in five human cell lines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Prostanoid signal transduction and gene expression in the endothelium: role in cardiovascular diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Specificity and mechanism of action of some commonly used protein kinase inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Retinoic acid signaling is essential for embryonic hematopoietic stem cell development

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

A blood flow-dependent klf2a-NO signaling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin+CD45+ pre-definitive HSCs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

All primitive and definitive hematopoietic progenitor cells emerging before E10 in the mouse embryo are products of the yolk sac.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

CREB regulates Meis1 expression in normal and malignant hematopoietic cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

High-resolution profiling of histone methylations in the human genome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

IFN-gamma activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4419355

Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization

26 September 2018

1 reference

12 December 2020

Onset of cardiac function during early mouse embryogenesis coincides with entry of primitive erythroblasts into the embryo proper

1 reference

12 December 2020

Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo

1 reference

12 December 2020

Shear-dependent inhibition of granulocyte adhesion to cultured endothelium by dextran sulfate

1 reference

12 December 2020

Definitive hematopoiesis is autonomously initiated by the AGM region

1 reference

12 December 2020

Defects in aortic fusion and craniofacial vasculature in the holoprosencephalic mouse embryo under inhibition of sonic hedgehog signaling

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20141514

1 reference

8 August 2017

1 reference

8 August 2017

1 reference