(Q35585451)

9 August 2017

title

Identification of an AMPK phosphorylation site in Drosophila TSC2 (gigas) that regulate cell growth (English)

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AMP-activated protein kinase alpha subunit Dmel_CG3051

9 August 2017

0 references

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GOA release 2020-03-11

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Myungjin Kim

1

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9 August 2017

Jun Hee Lee

series ordinal

2

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9 August 2017

language of work or name

English

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publication date

27 March 2015

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International Journal of Molecular Sciences

9 August 2017

published in

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9 August 2017

volume

16

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9 August 2017

issue

4

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9 August 2017

page(s)

7015-7026

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

27 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Sestrin2 inhibits mTORC1 through modulation of GATOR complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

12 July 2018

1 reference

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SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Sestrins inhibit mTORC1 kinase activation through the GATOR complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Regulation of mTORC1 by amino acids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging

12 July 2018

1 reference

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Quantitative phosphoproteomics reveal mTORC1 activates de novo pyrimidine synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

AMPK: a nutrient and energy sensor that maintains energy homeostasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Sestrin2 modulates AMPK subunit expression and its response to ionizing radiation in breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

12 July 2018

1 reference

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Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

An emerging role of mTOR in lipid biosynthesis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3,3'-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular protozoan parasite Leishmania donovani.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

AMPK phosphorylation of raptor mediates a metabolic checkpoint

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Energy-dependent regulation of cell structure by AMP-activated protein kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Upstream and downstream of mTOR

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

TSC2: filling the GAP in the mTOR signaling pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

TSC2 mediates cellular energy response to control cell growth and survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425001

26 September 2018

Identifiers

DOI

10.3390/IJMS16047015

1 reference

9 August 2017

1 reference

9 August 2017

1 reference