(Q35593776)

9 August 2017

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title

Genetic programming by the proteolytic fragments of the amyloid precursor protein: somewhere between confusion and clarity (English)

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9 August 2017

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1

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9 August 2017

Jeffrey A Johnson

2

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9 August 2017

publication date

1 January 2003

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Reviews in the Neurosciences

9 August 2017

published in

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9 August 2017

volume

14

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9 August 2017

issue

4

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9 August 2017

page(s)

317-341

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Remarkable increase in the concentration of 8-hydroxyguanosine in cerebrospinal fluid from patients with Alzheimer's disease

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Induction of neuroprotective kappa B-dependent transcription by secreted forms of the Alzheimer's beta-amyloid precursor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Co-ordinated and cellular specific induction of the components of the IGF/IGFBP axis in the rat brain following hypoxic-ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Binding of secreted human neuroblastoma proteoglycans to the Alzheimer's amyloid A4 peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Intraventricular infusions of antibodies to amyloid-beta-protein precursor impair the acquisition of a passive avoidance response in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

The caspase-derived C-terminal fragment of betaAPP induces caspase-independent toxicity and triggers selective increase of Abeta42 in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Increasing the complexity of coactivation in nuclear receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Involvement of amyloid precursor protein in memory formation in the rat: an indirect antibody approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Secreted form of beta-amyloid precursor protein activates protein kinase C and phospholipase Cgamma1 in cultured embryonic rat neocortical cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

The C-terminus of the beta protein is critical in amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Insulin-like growth factors-I and -II differentially regulate endogenous acetylcholine release from the rat hippocampal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Differential gene expression patterns revealed by oligonucleotide versus long cDNA arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Decorin attenuates gliotic scar formation in the rat cerebral hemisphere

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

A gene expression profile of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Neuroinflammatory signaling upregulation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Effect of the Alzheimer amyloid fragment Abeta(25-35) on Akt/PKB kinase and survival of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Neuroscience. New leads on the 'how' of Alzheimer's

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

CREB: a mediator of long-term memory from mollusks to mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Presenilin is required for activity and nuclear access of Notch in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

The role of presenilin cofactors in the gamma-secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Early induction of interleukin-6 mRNA in the hippocampus and cortex of APPsw transgenic mice Tg2576.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Cortical change in Alzheimer's disease detected with a disease-specific population-based brain atlas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Decreased levels of soluble amyloid beta-protein precursor in cerebrospinal fluid of live Alzheimer disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Amyloid precursor protein requires the insulin signaling pathway for neurotrophic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Distinct sites of insulin-like growth factor (IGF)-II expression and localization in lesioned rat brain: possible roles of IGF binding proteins (IGFBPs) in the mediation of IGF-II activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Identification of a mouse brain cDNA that encodes a protein related to the Alzheimer disease-associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Isolation and characterization of APLP2 encoding a homologue of the Alzheimer's associated amyloid beta protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP(SW) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Amyloid beta protein enhances the survival of hippocampal neurons in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Presenilins are not required for A beta 42 production in the early secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Negative regulation of transforming growth factor-beta by the proteoglycan decorin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

Selective cytotoxicity of intracellular amyloid beta peptide1-42 through p53 and Bax in cultured primary human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FREVNEURO.2003.14.4.317

10.1515/REVNEURO.2003.14.4.317

21 January 2018

Identifiers

DOI

1 reference

9 August 2017

1 reference