(Q35598383)

9 August 2017

title

Impact of Fgd1 and ddn diversity in Mycobacterium tuberculosis complex on in vitro susceptibility to PA-824. (English)

1 reference

Mycobacterium tuberculosis

9 August 2017

main subject

0 references

1 reference

Claudio U Köser

2

0 references

Marc A. Martí‐Renom

object named as

Marc A Marti-Renom

7

0 references

Sabine Rüsch-Gerdes

4

object named as

Sabine Rüsch-Gerdes

1 reference

9 August 2017

1

Silke Feuerriegel

1 reference

9 August 2017

Davide Baù

3

1 reference

9 August 2017

David K Summers

5

1 reference

9 August 2017

John A C Archer

6

1 reference

9 August 2017

Stefan Niemann

8

1 reference

9 August 2017

language of work or name

English

0 references

publication date

19 September 2011

1 reference

Antimicrobial Agents and Chemotherapy

9 August 2017

published in

1 reference

9 August 2017

volume

55

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9 August 2017

issue

12

1 reference

9 August 2017

page(s)

5718-5722

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Drugs in development for tuberculosis

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

PA-824 exhibits time-dependent activity in a murine model of tuberculosis

27 July 2018

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Clinical characteristics of the smooth tubercle bacilli ‘Mycobacterium canettii’ infection suggest the existence of an environmental reservoir

27 July 2018

1 reference

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Molecular characteristics of "Mycobacterium canettii" the smooth Mycobacterium tuberculosis bacilli

27 July 2018

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Massive gene duplication event among clinical isolates of the Mycobacterium tuberculosis W/Beijing family

27 July 2018

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Influence of M. tuberculosis lineage variability within a clinical trial for pulmonary tuberculosis

27 July 2018

1 reference

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Early bactericidal activity and pharmacokinetics of PA-824 in smear-positive tuberculosis patients

27 July 2018

1 reference

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27 July 2018

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Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

27 July 2018

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Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects

27 July 2018

1 reference

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High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography

27 July 2018

1 reference

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PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release

27 July 2018

1 reference

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27 July 2018

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A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents

27 July 2018

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OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice

27 July 2018

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Structural violence and clinical medicine

27 July 2018

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Mycobacterium leprae is naturally resistant to PA-824

27 July 2018

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Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-Coffee

27 July 2018

1 reference

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Multicenter laboratory validation of the BACTEC MGIT 960 technique for testing susceptibilities of Mycobacterium tuberculosis to classical second-line drugs and newer antimicrobials

27 July 2018

1 reference

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Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis

27 July 2018

1 reference

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The Universal Protein Resource (UniProt): an expanding universe of protein information

27 July 2018

1 reference

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Ancient origin and gene mosaicism of the progenitor of Mycobacterium tuberculosis

27 July 2018

1 reference

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Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages

27 July 2018

1 reference

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Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis

27 July 2018

1 reference

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Alignment of protein sequences by their profiles

27 July 2018

1 reference

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Genetic requirements for mycobacterial survival during infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Genes required for mycobacterial growth defined by high density mutagenesis

27 July 2018

1 reference

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Genome-wide analysis of synonymous single nucleotide polymorphisms in Mycobacterium tuberculosis complex organisms: resolution of genetic relationships among closely related microbial strains.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Demonstration that fbiC is required by Mycobacterium bovis BCG for coenzyme F(420) and FO biosynthesis

27 July 2018

1 reference

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Use of transposon Tn5367 mutagenesis and a nitroimidazopyran-based selection system to demonstrate a requirement for fbiA and fbiB in coenzyme F(420) biosynthesis by Mycobacterium bovis BCG

27 July 2018

1 reference

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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Comparative protein modelling by satisfaction of spatial restraints

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Occurrence and stability of insertion sequences in Mycobacterium tuberculosis complex strains: evaluation of an insertion sequence-dependent DNA polymorphism as a tool in the epidemiology of tuberculosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Half-century-old TB drugs get a facelift in new cocktails

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

The mechanism of action of PA-824: Novel insights from transcriptional profiling

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Microbiology. An antibiotic mimics immunity

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Crystal structures of F420-dependent glucose-6-phosphate dehydrogenase FGD1 involved in the activation of the anti-tuberculosis drug candidate PA-824 reveal the basis of coenzyme and substrate binding

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

In vitro and in vivo activities of rifampin, streptomycin, amikacin, moxifloxacin, R207910, linezolid, and PA-824 against Mycobacterium ulcerans.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3232757

26 September 2018

Identifiers

DOI

10.1128/AAC.05500-11

1 reference

9 August 2017

1 reference

9 August 2017

1 reference