(Q35671690)

9 August 2017

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title

Death by Abl: a matter of location (English)

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9 August 2017

Jiangyu Zhu

1

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9 August 2017

Jean Y J Wang

series ordinal

2

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9 August 2017

publication date

1 January 2004

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Current Topics in Developmental Biology

9 August 2017

published in

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9 August 2017

volume

59

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9 August 2017

page(s)

165-192

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Cell cycle checkpoint signaling through the ATM and ATR kinases

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mechanisms of autoinhibition and STI-571/imatinib resistance revealed by mutagenesis of BCR-ABL.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mdm2 binds p73 alpha without targeting degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Caspase-dependent cleavage of c-Abl contributes to apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Coordinated regulation of life and death by RB.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Signal-dependent protection from apoptosis in mice expressing caspase-resistant Rb.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Inhibiting the p53-MDM2 interaction: an important target for cancer therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Activation of c-Abl tyrosine kinase requires caspase activation and is not involved in JNK/SAPK activation during apoptosis of human monocytic leukemia U937 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The Fanconi anaemia/BRCA pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

JAK-STAT signaling activated by Abl oncogenes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Crk family adaptors-signalling complex formation and biological roles

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

CRM1 is an export receptor for leucine-rich nuclear export signals

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to Hepatocyte Growth Factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

V(D)J recombination: RAG proteins, repair factors, and regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The MDM2 RING-finger domain is required to promote p53 nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Functional plasticity of CH domains.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A myristoyl/phosphotyrosine switch regulates c-Abl

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Variation on an Src-like theme

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A comparison of the activity, sequence specificity, and CRM1-dependence of different nuclear export signals

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Inhibition of cell migration by Abl family tyrosine kinases through uncoupling of Crk-CAS complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Functional interaction between DNA-PK and c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Essential roles for the Abl and Arg tyrosine kinases in neurulation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Nuclear transport and transcription

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mice deficient in Abl are osteoporotic and have defects in osteoblast maturation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Three distinct signalling responses by murine fibroblasts to genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

p73: Friend or foe in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The p53-Mdm2 module and the ubiquitin system.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Structural basis for the autoinhibition of c-Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A new link between the c-Abl tyrosine kinase and phosphoinositide signalling through PLC-gamma1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A myogenic differentiation checkpoint activated by genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mechanisms underlying abnormal trafficking and expansion of malignant progenitors in CML: BCR/ABL-induced defects in integrin function in CML.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

BCR/ABL induces multiple abnormalities of cytoskeletal function

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Mechanisms of caspase activation and inhibition during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Autoinhibition of Bcr-Abl through its SH3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Exportin 1 (Crm1p) is an essential nuclear export factor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

An atomic model for actin binding by the CH domains and spectrin-repeat modules of utrophin and dystrophin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

c-Abl tyrosine kinase is not essential for ataxia telangiectasia mutated functions in chromosomal maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The caspase family of cysteine proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Exclusion of c-Abl from the Nucleus Restrains the p73 Tumor Suppression Function

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

1 reference

7 January 2021

Regulation of cell death by the Abl tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

The biology of chronic myelogenous leukemia:mouse models and cell adhesion.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Inhibition of c-Abl tyrosine kinase activity by filamentous actin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Interactions of the Nijmegen breakage syndrome protein with ATM and BRCA1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM(-/-) and c-Abl(-/-) cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

Regulation of Rad51 function by c-Abl in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

MDM2 suppresses p73 function without promoting p73 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

NF-AT activation requires suppression of Crm1-dependent export by calcineurin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2959007-5

7 January 2021

10.1016/S0070-2153(04)59007-5

Identifiers

DOI

1 reference

9 August 2017

1 reference