(Q35753361)

10 August 2017

1 reference

title

Gastrointestinal pain in functional bowel disorders: sensory neurons as novel drug targets (English)

1 reference

10 August 2017

Peter Holzer

1

1 reference

10 August 2017

language of work or name

English

0 references

publication date

1 April 2004

1 reference

Expert Opinion on Therapeutic Targets

10 August 2017

published in

1 reference

10 August 2017

volume

8

1 reference

10 August 2017

issue

2

1 reference

10 August 2017

page(s)

107-123

1 reference

The burden of selected digestive diseases in the United States.

10 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Systematic review: the economic impact of irritable bowel syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Mediators and pharmacology of visceral sensitivity: from basic to clinical investigations

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gastrointestinal perception: pathophysiological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gastrointestinal afferents as targets of novel drugs for the treatment of functional bowel disorders and visceral pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Sensory neurone responses to mucosal noxae in the upper gut: relevance to mucosal integrity and gastrointestinal pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Functional and chemical anatomy of the afferent vagal system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Clinical and pathophysiological characteristics of acute-onset functional dyspepsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gastric mucosal mast cells are increased in Helicobacter pylori-negative functional dyspepsia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Involvement of spinal calcitonin gene-related peptide in the development of acute visceral hyperalgesia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gastric inflammation triggers hypersensitivity to acid in awake rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Immune-mediated neural dysfunction in a murine model of chronic Helicobacter pylori infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

An update of the Cochrane systematic review of Helicobacter pylori eradication therapy in nonulcer dyspepsia: resolving the discrepancy between systematic reviews.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Effect of Helicobacter pylori eradication on development of dyspeptic and reflux disease in healthy asymptomatic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Neuronal plasticity: increasing the gain in pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Nerve growth factor and gastric hyperalgesia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Interleukin 10 genotypes in irritable bowel syndrome: evidence for an inflammatory component?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Increased rectal mucosal expression of interleukin 1beta in recently acquired post-infectious irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Medically unexplained physical symptoms, anxiety, and depression: a meta-analytic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Abdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Differences in expression of oligosaccharides, neuropeptides, carbonic anhydrase and neurofilament in rat primary afferent neurons retrogradely labelled via skin, muscle or visceral nerves

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

NMDA receptors as targets for drug action in neuropathic pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Irritable bowel syndrome: new agents targeting serotonin receptor subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Patients with constipation-predominant irritable bowel syndrome (IBS) may have elevated serotonin concentrations in colonic mucosa as compared with diarrhea-predominant patients and subjects with normal bowel habits

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Serotoninergic neuroenteric modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The role of IP prostanoid receptors in inflammatory pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Prostaglandin receptor subtypes, EP3C and EP4, mediate the prostaglandin E2-induced cAMP production and sensitization of sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The role of prostaglandins in the bradykinin-induced activation of serosal afferents of the rat jejunum in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The prostaglandin E2 receptor-1 (EP-1) mediates acid-induced visceral pain hypersensitivity in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Proteinases and proteinase-activated receptor 2: a possible role to promote visceral hyperalgesia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gastrointestinal functions of proteinase-activated receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

P2X receptors in peripheral neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Changes in P2X receptor responses of sensory neurons from P2X3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Purine-mediated signalling in pain and visceral perception

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Excitatory effect of P2X receptor activation on mesenteric afferent nerves in the anaesthetised rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Diadenosine pentaphosphate is more potent than ATP at P2X receptors in isolated rat vagus nerve

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Purinergic mechanisms contribute to mechanosensory transduction in the rat colorectum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

P2X purinoceptor-induced sensitization of ferret vagal mechanoreceptors in oesophageal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Acid-sensitive ion channels in gastrointestinal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

ATP-gated ion channel P2X(3) is increased in human inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

P2 receptors in the murine gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

TNP-ATP, a potent P2X3 receptor antagonist, blocks acetic acid-induced abdominal constriction in mice: comparison with reference analgesics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

TRP channels as cellular sensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The capsaicin receptor: a heat-activated ion channel in the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

ThermoTRP channels and beyond: mechanisms of temperature sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The vanilloid receptor: a molecular gateway to the pain pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Endovanilloid signaling in pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The diversity in the vanilloid (TRPV) receptor family of ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Induction of vanilloid receptor channel activity by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Nociceptor excitation by thermal sensitization--a hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Impaired nociception and pain sensation in mice lacking the capsaicin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Neural emergency system in the stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Chemical coding of neurons expressing delta- and kappa-opioid receptor and type I vanilloid receptor immunoreactivities in the porcine ileum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Distribution and characterization of vanilloid receptors in the rat stomach

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gut pain and hyperalgesia induced by capsaicin: a human experimental model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

A new model of visceral pain and referred hyperalgesia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Vanilloid (capsaicin) receptors in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Visceral pain reflex after pretreatment with capsaicin and morphine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Role of nerve growth factor in the trinitrobenzene sulfonic acid-induced colonic hypersensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Topical capsaicin--a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The treatment of functional dyspepsia with red pepper

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Chili pepper and rectal hyperalgesia in irritable bowel syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The capsaicin VR1 receptor mediates substance P release in toxin A-induced enteritis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Vanilloid receptor-1 containing primary sensory neurones mediate dextran sulphate sodium induced colitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

H(+)-gated cation channels: neuronal acid sensors in the NaC/DEG family of ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Functional implications of the localization and activity of acid-sensitive channels in rat peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Biochemical basis of touch perception: mechanosensory function of degenerin/epithelial Na+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The mammalian sodium channel BNC1 is required for normal touch sensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

The DRASIC cation channel contributes to the detection of cutaneous touch and acid stimuli in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Involvement of stretch-sensitive calcium flux in mechanical transduction in visceral afferents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Impaired Pressure Sensation in Mice Lacking TRPV4

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

TREK-2, a new member of the mechanosensitive tandem-pore K+ channel family

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Intravenous lidocaine inhibits visceral nociceptive reflexes and spinal neurons in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Amitriptyline inhibits voltage-sensitive sodium currents in rat gastric sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Distinct potassium channels on pain-sensing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Gabapentin markedly reduces acetic acid-induced visceral nociception

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

An evaluation of intrathecal ziconotide for the treatment of chronic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Role of calcium channels in the spinal transmission of nociceptive information from the mesentery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Vagal afferent signaling of a gastric mucosal acid insult to medullary, pontine, thalamic, hypothalamic and limbic, but not cortical, nuclei of the rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Attenuation of thermal nociception and hyperalgesia by VR1 blockers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

High affinity antagonists of the vanilloid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

N-(3-acyloxy-2-benzylpropyl)-N'-[4-(methylsulfonylamino)benzyl]thiourea analogues: novel potent and high affinity antagonists and partial antagonists of the vanilloid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

4-(2-Pyridyl)piperazine-1-carboxamides: potent vanilloid receptor 1 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Identification and characterisation of SB-366791, a potent and selective vanilloid receptor (VR1/TRPV1) antagonist.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

7-Hydroxynaphthalen-1-yl-urea and -amide antagonists of human vanilloid receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

Major roles of prostanoid receptors IP and EP3 in endotoxin-induced enhancement of pain perception11Abbreviations:, prostaglandin E receptor subtype 1; IP, prostaglandin I receptor; LPS, lipopolysaccharide; and WT, wild-type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.8.2.107

21 January 2018

Identifiers

DOI

10.1517/14728222.8.2.107

1 reference

10 August 2017

1 reference