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Modulation of TRAIL signaling for cancer therapy
scientific article published on January 2004
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Modulation of TRAIL signaling for cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
author
Klaus-Michael Debatin
series ordinal
2
object named as
Klaus-Michael Debatin
0 references
Simone Fulda
series ordinal
1
object named as
Simone Fulda
0 references
publication date
1 January 2004
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
published in
Vitamins and Hormones
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
volume
67
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
page(s)
275-290
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
cites work
Genomic organization and mutation analyses of the DR5/TRAIL receptor 2 gene in colorectal carcinomas
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
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7 January 2021
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inferred from DOI database lookup
Safety and antitumor activity of recombinant soluble Apo2 ligand
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
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inferred from DOI database lookup
Disruption of NF-kappaB signaling reveals a novel role for NF-kappaB in the regulation of TNF-related apoptosis-inducing ligand expression
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
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7 January 2021
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inferred from DOI database lookup
Sensitization of resistant lymphoma cells to irradiation-induced apoptosis by the death ligand TRAIL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-kappaB pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemotherapy: targeting the mitochondrial cell death pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insights into cancer therapeutic design based on p53 and TRAIL receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptor signaling in cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of tumor necrosis factor apoptosis-inducing ligand- induced NF-kappa B activation by inhibition of apical caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The biochemistry of apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis: a link between cancer genetics and chemotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of NF-kappaB activity enhances TRAIL mediated apoptosis in breast cancer cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apo2L/TRAIL and its death and decoy receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic mutations of TRAIL-receptor 1 and TRAIL-receptor 2 genes in non-Hodgkin's lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel receptor for Apo2L/TRAIL contains a truncated death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-independent upregulation of KILLER/DR5 TRAIL receptor expression by glucocorticoids and interferon-gamma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TRAIL decoy receptor TRUNDD (DcR2, TRAIL-R4) is induced by adenovirus-p53 overexpression and can delay TRAIL-, p53-, and KILLER/DR5-dependent colon cancer apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT-1-independent upregulation of FADD and procaspase-3 and -8 in cancer cells treated with cytotoxic drugs.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptotic DNA fragmentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sensitization to TRAIL-induced apoptosis and modulation of FLICE-inhibitory protein in B chronic lymphocytic leukemia by actinomycin D.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell surface Death Receptor signaling in normal and cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The receptor for the cytotoxic ligand TRAIL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of death receptor expression and TRAIL/Apo2L-induced apoptosis by NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CCNU-dependent potentiation of TRAIL/Apo2L-induced apoptosis in human glioma cells is p53-independent but may involve enhanced cytochrome c release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IAP proteins: blocking the road to death's door
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosome: the seven-spoked death machine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-kappaB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nature's TRAIL--on a path to cancer immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 transactivates the KILLER/DR5 gene through an intronic sequence-specific DNA-binding site.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in the pathogenesis and treatment of disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: enemies within
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF-related apoptosis inducing ligand (TRAIL) and its receptors in tumor surveillance and cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and characterization of a new member of the TNF family that induces apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967015-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0083-6729(04)67015-4
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
PubMed ID
15110182
1 reference
stated in
Europe PubMed Central
PubMed ID
15110182
retrieved
10 August 2017
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