(Q35757146)

10 August 2017

title

Insulin transactivator MafA regulates intrathymic expression of insulin and affects susceptibility to type 1 diabetes (English)

1 reference

https://api.crossref.org/works/10.2337/DB10-0476

10 August 2017

Insulin Transactivator MafA Regulates Intrathymic Expression of Insulin and Affects Susceptibility to Type 1 Diabetes (English)

1 reference

16 June 2024

0 references

1

Shinsuke Noso

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

16 June 2024

4

Naru Babaya

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

16 June 2024

9

Takashi Kudo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

16 June 2024

author name string

Kohsuke Kataoka

2

1 reference

10 August 2017

Yumiko Kawabata

3

1 reference

10 August 2017

Yoshihisa Hiromine

5

1 reference

10 August 2017

Kaori Yamaji

6

1 reference

10 August 2017

Tomomi Fujisawa

7

1 reference

10 August 2017

Shinsaku Aramata

8

1 reference

10 August 2017

Satoru Takahashi

10

1 reference

10 August 2017

Hiroshi Ikegami

11

1 reference

10 August 2017

language of work or name

English

0 references

publication date

3 August 2010

1 reference

full work available at URL

10 August 2017

https://diabetesjournals.org/diabetes/article-pdf/59/10/2579/397838/zdb01010002579.pdf

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20682694/pdf/?tool=EBI

16 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20682694/?tool=EBI

16 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

http://intl-diabetes.diabetesjournals.org/cgi/content/abstract/59/10/2579

16 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

https://europepmc.org/articles/PMC3279543

16 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

https://europepmc.org/articles/PMC3279543?pdf=render

16 June 2024

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20682694

https://journals.org/diabetes/diabetes/article-pdf/59/10/2579/397838/zdb01010002579.pdf

16 June 2024

https://api.crossref.org/works/10.2337/DB10-0476

1 reference

https://diabetesjournals.org/diabetes/article-pdf/59/10/2579/397838/zdb01010002579.pdf

16 June 2024

https://api.crossref.org/works/10.2337/DB10-0476

1 reference

16 June 2024

1 reference

10 August 2017

volume

59

1 reference

10 August 2017

issue

10

1 reference

10 August 2017

page(s)

2579-2587

1 reference

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

10 August 2017

copyright license

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

1 reference

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Genetics of type 1A diabetes

2 October 2017

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Detecting shared pathogenesis from the shared genetics of immune-related diseases

2 October 2017

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Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci

2 October 2017

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A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene

2 October 2017

1 reference

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Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes

2 October 2017

1 reference

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Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels

2 October 2017

1 reference

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Regulation of immunity by self-reactive T cells

2 October 2017

1 reference

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Cellular and genetic mechanisms of self tolerance and autoimmunity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

MafA is a key regulator of glucose-stimulated insulin secretion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Chromosomal clustering of genes controlled by the aire transcription factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The stages of type 1A diabetes: 2005.

2 October 2017

1 reference

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Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The MafA transcription factor appears to be responsible for tissue-specific expression of insulin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Projection of an immunological self shadow within the thymus by the aire protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Cblb is a major susceptibility gene for rat type 1 diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families

2 October 2017

1 reference

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Type 1 diabetes: new perspectives on disease pathogenesis and treatment

2 October 2017

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Regulation of insulin gene expression by the IDDM associated, insulin locus haplotype

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Transactivation activity of Maf nuclear oncoprotein is modulated by Jun, Fos and small Maf proteins.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Regulation of insulin gene expression by cytokines and cell-cell interactions in mouse medullary thymic epithelial cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Proinsulin expression by Hassall's corpuscles in the mouse thymus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

MafA has strong cell transforming ability but is a weak transactivator

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

beta-cell neogenesis induced by adenovirus-mediated gene delivery of transcription factor pdx-1 into mouse pancreas.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The minisatellite in the diabetes susceptibility locus IDDM2 regulates insulin transcription.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

Association of the CT60 marker of the CTLA4 gene with systemic lupus erythematosus

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3279543

The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1

23 October 2018

1 reference

12 December 2020

Low expression of insulin in the thymus of non-obese diabetic mice

1 reference

12 December 2020

An improved method for isolation of mouse pancreatic islets

1 reference

12 December 2020

Intrathymic expression of genes involved in organ specific autoimmune disease

1 reference

12 December 2020

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

1 reference

12 December 2020

Dendritic cells in human thymus and periphery display a proinsulin epitope in a transcription-dependent, capture-independent fashion

1 reference

12 December 2020

Insulin alleles and autoimmune regulator (AIRE) gene expression both influence insulin expression in the thymus

1 reference

12 December 2020

Isolation and characterization of proinsulin-producing medullary thymic epithelial cell clones

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB10-0476

1 reference

10 August 2017

1 reference

10 August 2017

1 reference