(Q35778505)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

0 references

3

1 reference

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24 February 2020

author name string

Sanjeev Shukla

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Eswar Shankar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Gregory T MacLennan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Sanjay Gupta

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

language of work or name

English

0 references

publication date

17 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

10

1 reference

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24 February 2020

issue

9

1 reference

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24 February 2020

page(s)

e0138710

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons CC0 License

24 February 2020

copyright license

start time

17 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

Cancer statistics, 2015

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Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer.

12 July 2018

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Regulation of Mcl-1 by constitutive activation of NF-κB contributes to cell viability in human esophageal squamous cell carcinoma cells

12 July 2018

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Plant phytochemicals as epigenetic modulators: role in cancer chemoprevention

12 July 2018

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Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway

12 July 2018

1 reference

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Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives

12 July 2018

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NF-κB regulates mesenchymal transition for the induction of non-small cell lung cancer initiating cells

12 July 2018

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Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.

12 July 2018

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Apigenin induces c-Myc-mediated apoptosis in FRO anaplastic thyroid carcinoma cells

12 July 2018

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Apigenin-induced apoptosis in A375 and A549 cells through selective action and dysfunction of mitochondria

12 July 2018

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Flavonoids, flavonoid subclasses and breast cancer risk: a meta-analysis of epidemiologic studies

12 July 2018

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Interactions of isoflavones and other plant derived estrogens with estrogen receptors for prevention and treatment of breast cancer-considerations concerning related efficacy and safety.

12 July 2018

1 reference

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Targeting the PI3K/Akt/mTOR axis by apigenin for cancer prevention

12 July 2018

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Flavonoids and cancer prevention: a review of the evidence

12 July 2018

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Expression of BCL10 in cervical cancer has a role in the regulation of cell growth through the activation of NF-κB-dependent cyclin D1 signaling

12 July 2018

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Apigenin induces apoptosis via extrinsic pathway, inducing p53 and inhibiting STAT3 and NFκB signaling in HER2-overexpressing breast cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Dual blockade of PKA and NF-κB inhibits H2 relaxin-mediated castrate-resistant growth of prostate cancer sublines and induces apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

A mechanism of apigenin-induced apoptosis is potentially related to anti-angiogenesis and anti-migration in human hepatocellular carcinoma cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Association of prostate cancer risk Loci with disease aggressiveness and prostate cancer-specific mortality

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy

12 July 2018

1 reference

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NF-κB addiction and its role in cancer: 'one size does not fit all'.

12 July 2018

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Apigenin: a promising molecule for cancer prevention

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Apigenin induces apoptosis via downregulation of S-phase kinase-associated protein 2-mediated induction of p27Kip1 in primary effusion lymphoma cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

NF-kappaB and cancer: how intimate is this relationship

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Targeting transcription factor NFkappaB: comparative analysis of proteasome and IKK inhibitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Flavonoid intake and ovarian cancer risk in a population-based case-control study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Mechanism of CYP2C9 inhibition by flavones and flavonols

12 July 2018

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The two-faced NF-kappaB in the skin.

12 July 2018

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Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation

12 July 2018

1 reference

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The role of the NFkappaB signalling pathway in cancer

12 July 2018

1 reference

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Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-Akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

12 July 2018

1 reference

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Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Nuclear factor-kappaB in cancer development and progression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Circuitry of nuclear factor kappaB signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Bioavailability of apigenin from apiin-rich parsley in humans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Nuclear factor-kappaB/p65 (Rel A) is constitutively activated in human prostate adenocarcinoma and correlates with disease progression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Suppression of constitutive and tumor necrosis factor alpha-induced nuclear factor (NF)-kappaB activation and induction of apoptosis by apigenin in human prostate carcinoma PC-3 cells: correlation with down-regulation of NF-kappaB-responsive genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Dietary flavonoids: bioavailability, metabolic effects, and safety

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

NF-kappaB and cell-cycle regulation: the cyclin connection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

The prognostic significance of p34cdc2 and cyclin D1 protein expression in prostate adenocarcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Are biochemical recurrence outcomes similar after radical prostatectomy and radiation therapy? Analysis of prostate cancer-specific mortality by nomogram-predicted risks of biochemical recurrence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Nuclear expression of glioma-associated oncogene homolog 1 and nuclear factor-κB is associated with a poor prognosis of pancreatic cancer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Dietary flavonoid intake and colorectal cancer: a case-control study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Pharmacokinetics and metabolism of apigenin in female and male rats after a single oral administration

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Expression of nuclear factor-kappa B and I kappa B alpha proteins in prostatic adenocarcinomas: correlation of nuclear factor-kappa B immunoreactivity with disease recurrence

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Metabolism of flavonoids via enteric recycling: mechanistic studies of disposition of apigenin in the Caco-2 cell culture model

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Mechanisms of constitutive NF-kappaB activation in human prostate cancer cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574560

Flavonoids and Prostate Cancer Risk: A Study in Italy

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0138710

NF-κB nuclear localization and its prognostic significance in prostate cancer

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0138710

Nuclear Localization of Nuclear Factor- B p65 in Primary Prostate Tumors Is Highly Predictive of Pelvic Lymph Node Metastases

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0138710

The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells

21 January 2018

1 reference

12 December 2020

Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model

1 reference

12 December 2020

The role of HER2/neu, BCL2, p53 genes and proliferating cell nuclear protein as molecular prognostic parameters in localized prostate carcinoma

1 reference

12 December 2020

Effects of the flavonoids quercetin and apigenin on hemostasis in healthy volunteers: results from an in vitro and a dietary supplement study

1 reference

12 December 2020

Constitutive activation of P I3 K-Akt and NF-kappaB during prostate cancer progression in autochthonous transgenic mouse model

1 reference

12 December 2020

Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice

1 reference

12 December 2020

Dietary flavonoids: intake, health effects and bioavailability

1 reference

12 December 2020

Effect of parsley (Petroselinum crispum) intake on urinary apigenin excretion, blood antioxidant enzymes and biomarkers for oxidative stress in human subjects

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0138710

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

26379052

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26379052%20AND%20SRC:MED&resulttype=core&format=json