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Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer.
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scholarly article
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Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
title
Apigenin induces apoptosis by targeting inhibitor of apoptosis proteins and Ku70-Bax interaction in prostate cancer
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
main subject
apoptotic process
0 references
prostate cancer
1 reference
based on heuristic
inferred from title
author
Pingfu Fu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
author name string
Sanjeev Shukla
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
Sanjay Gupta
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
language of work or name
English
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publication date
1 May 2014
1 reference
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Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
published in
Apoptosis
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
volume
19
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
page(s)
883-894
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
exact match
https://scigraph.springernature.com/pub.10.1007/s10495-014-0971-6
0 references
cites work
Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Efficacy of intermittent androgen deprivation therapy vs conventional continuous androgen deprivation therapy for advanced prostate cancer: a meta-analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Management of biochemical recurrence after primary treatment of prostate cancer: a systematic review of the literature
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Cancer statistics, 2013
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Green tea polyphenols induce p53-dependent and p53-independent apoptosis in prostate cancer cells through two distinct mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Histone deacetylase inhibitors disrupt the mitotic spindle assembly checkpoint by targeting histone and nonhistone proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Apigenin attenuates insulin-like growth factor-I signaling in an autochthonous mouse prostate cancer model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Garlic constituent diallyl trisulfide suppresses x-linked inhibitor of apoptosis protein in prostate cancer cells in culture and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Apigenin: a promising molecule for cancer prevention
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Role of IAPs in prostate cancer progression: immunohistochemical study in normal and pathological (benign hyperplastic, prostatic intraepithelial neoplasia and cancer) human prostate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Apoptosis by dietary agents for prevention and treatment of prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Prostate cancer: the new landscape
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
IAP-targeted therapies for cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
IAPs: more than just inhibitors of apoptosis proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
The biology of Ku and its potential oncogenic role in cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
How the Bcl-2 family of proteins interact to regulate apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
XIAP as target for therapeutic apoptosis in prostate cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Survivin expression is associated with features of biologically aggressive prostate carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Flavonoid intake and breast cancer risk: a case--control study in Greece
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Ku70 suppresses the apoptotic translocation of Bax to mitochondria.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Antiapoptotic proteins. The bcl-2 and inhibitor of apoptosis protein families
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
9 September 2017
Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Molecular targeting of Bcl-2 overcomes prostate cancer cell adaptation to XIAP gene downregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Apigenin-induced cell cycle arrest is mediated by modulation of MAPK, PI3K-Akt, and loss of cyclin D1 associated retinoblastoma dephosphorylation in human prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
Elevated expression of inhibitor of apoptosis proteins in prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
14 September 2017
The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
17 June 2018
Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
17 June 2018
Dietary flavonoid intake and colorectal cancer: a case-control study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Flavonoids intake and risk of lung cancer: a meta-analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Perturbation of the chromosomal binding of RCC1, Mad2 and survivin causes spindle assembly defects and mitotic catastrophe
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
An antisense oligonucleotide to cIAP-1 sensitizes prostate cancer cells to fas and TNFalpha mediated apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Molecular mechanisms for apigenin-induced cell-cycle arrest and apoptosis of hormone refractory human prostate carcinoma DU145 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Inhibitors of apoptosis proteins in prostate cancer cell lines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3997183
retrieved
22 August 2018
Blockade of beta-catenin signaling by plant flavonoid apigenin suppresses prostate carcinogenesis in TRAMP mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24563225
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dietary flavonoids: intake, health effects and bioavailability
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24563225
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1007/S10495-014-0971-6
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
Fatcat ID
release_qzs3j7zl3ba5bduuehifie63me
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/qzs3j7zl3ba5bduuehifie63me
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
3997183
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
PubMed ID
24563225
1 reference
stated in
Europe PubMed Central
PMCID
3997183
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24563225%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 March 2020
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