(Q35847813)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Potential compounds for the treatment of mitochondrial disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

Douglass Matthew Turnbull

1 March 2020

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

P K Rai

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

R N Lightowlers

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

1 reference

20 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

published in

British Medical Bulletin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

116

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

5-18

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

Development of pharmacological strategies for mitochondrial disorders

1 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Sequence and organization of the human mitochondrial genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Prevalence of nuclear and mitochondrial DNA mutations related to adult mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Update on clinical aspects and treatment of selected vitamin-responsive disorders II (riboflavin and CoQ 10).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

A randomized trial of coenzyme Q10 in mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

A modern approach to the treatment of mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Design and implementation of the first randomized controlled trial of coenzyme CoQ₁₀ in children with primary mitochondrial diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Inhibition of lipid peroxidation by a novel compound (CV-2619) in brain mitochondria and mode of action of the inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Treatment of mitochondrial disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Persistence of the treatment effect of idebenone in Leber's hereditary optic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Idebenone treatment in Leber's hereditary optic neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Carnitine Palmitoyltransferase II Deficiency: A Clinical, Biochemical, and Molecular Review

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

L-carnitine and creatine in Friedreich's ataxia. A randomized, placebo-controlled crossover trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Carnitine, mitochondrial function and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Long-term safety of dichloroacetate in congenital lactic acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Dichloroacetate causes toxic neuropathy in MELAS: a randomized, controlled clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Mitochondrial bioenergetics and therapeutic intervention in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Initial experience in the treatment of inherited mitochondrial disease with EPI-743.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Review of clinical trials for mitochondrial disorders: 1997-2012.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Oxidative stress biomarkers in mitochondrial myopathies, basally and after cysteine donor supplementation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Effect of the triaminopyridine flupirtine on calcium uptake, membrane potential and ATP synthesis in rat heart mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Antioxidant properties of the triaminopyridine, flupirtine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Free-radical scavenging and mitochondrial antioxidant activities of Reishi-Ganoderma lucidum (Curt: Fr) P. Karst and Arogyapacha-Trichopus zeylanicus Gaertn extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Activating mitochondrial regulator PGC-1α expression by astrocytic NGF is a therapeutic strategy for Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Targeting mitochondrial cardiolipin and the cytochrome c/cardiolipin complex to promote electron transport and optimize mitochondrial ATP synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

PGC-1alpha: a key regulator of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

RETRACTED: Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Turn up the power - pharmacological activation of mitochondrial biogenesis in mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Long-term follow-up of bezafibrate treatment in patients with the myopathic form of carnitine palmitoyltransferase 2 deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Rheb and mammalian target of rapamycin in mitochondrial homoeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Pharmacological approaches to restore mitochondrial function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Screening for active small molecules in mitochondrial complex I deficient patient's fibroblasts, reveals AICAR as the most beneficial compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Isoflavones promote mitochondrial biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Genistein and folic acid prevent oxidative injury induced by β-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Therapeutic approaches to mitochondrial dysfunction in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

SirT3 is a nuclear NAD+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

NAD(+)-dependent activation of Sirt1 corrects the phenotype in a mouse model of mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Current options in the treatment of mitochondrial diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Molecular pathology of MELAS and L-arginine effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Mitochondria: role of citrulline and arginine supplementation in MELAS syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Citrulline and arginine utility in treating nitric oxide deficiency in mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Abnormal myocardial energy-production state in mitochondrial cardiomyopathy and acute response to L-arginine infusion. C-11 acetate kinetics revealed by positron emission tomography

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

L-Arginine Affects Aerobic Capacity and Muscle Metabolism in MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes) Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

Screening of effective pharmacological treatments for MELAS syndrome using yeasts, fibroblasts and cybrid models of the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

The neuro-ophthalmology of mitochondrial disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBMB%2FLDV046

21 January 2018

Identifiers

DOI

10.1093/BMB/LDV046

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26590387%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference