(Q35951508)

11 August 2017

1 reference

title

Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance (English)

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11 August 2017

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1

Katalin Karikó

1 reference

11 August 2017

2

Drew Weissman

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11 August 2017

Frank A Welsh

3

1 reference

11 August 2017

publication date

1 November 2004

1 reference

Journal of Cerebral Blood Flow & Metabolism

11 August 2017

published in

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11 August 2017

volume

24

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11 August 2017

issue

11

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11 August 2017

page(s)

1288-1304

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Multiple levels of regulation of the interleukin-6 system in stroke

11 August 2017

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Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction

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21 January 2018

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21 January 2018

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Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding

21 January 2018

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Immunostimulatory CpG-DNA activates murine microglia

21 January 2018

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Cerebrovascular hemodynamics and ischemic tolerance: lipopolysaccharide-induced resistance to focal cerebral ischemia is not due to changes in severity of the initial ischemic insult, but is associated with preservation of microvascular perfusion

21 January 2018

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Isoflurane pretreatment inhibits cytokine-induced cell death in cultured rat smooth muscle cells and human endothelial cells

21 January 2018

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Xenon and isoflurane differentially modulate lipopolysaccharide-induced activation of the nuclear transcription factor KB and production of tumor necrosis factor-alpha and interleukin-6 in monocytes.

21 January 2018

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Neutrophil elastase up-regulates interleukin-8 via toll-like receptor 4.

21 January 2018

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Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades

21 January 2018

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Ischemic tolerance and endogenous neuroprotection

21 January 2018

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TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts

21 January 2018

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Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.

21 January 2018

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Molecular mechanisms of endotoxin tolerance

21 January 2018

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Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium

21 January 2018

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PI3K and negative regulation of TLR signaling.

21 January 2018

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Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes

21 January 2018

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An essential role for albumin in the interaction of endotoxin with lipopolysaccharide-binding protein and sCD14 and resultant cell activation

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Halothane reduces the early lipopolysaccharide-induced lung inflammation in mechanically ventilated rats.

21 January 2018

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The Effects of Drugs on Membrane Fluidity

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Response of human pulmonary epithelial cells to lipopolysaccharide involves Toll-like receptor 4 (TLR4)-dependent signaling pathways: evidence for an intracellular compartmentalization of TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Desflurane affords greater protection than halothane against focal cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Role of lipid-modifying therapy in the prevention of initial and recurrent stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Up-regulation of endothelial nitric oxide synthase via phosphatidylinositol 3-kinase pathway contributes to ischemic tolerance in the CA1 subfield of gerbil hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Cytokine production after whole body and localized hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Ethanol decreases natural killer cell activation but only minimally affects anatomical distribution after administration of polyinosinic:polycytidylic acid: role in resistance to B16F10 melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

TLR-induced negative regulatory circuits: role of suppressor of cytokine signaling (SOCS) proteins in innate immunity

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Lipopolysaccharide pretreatment protects from renal ischemia/reperfusion injury : possible connection to an interleukin-6-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Cortical spreading depression induces proinflammatory cytokine gene expression in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression

21 January 2018

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Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

N-methyl-D-aspartate and TrkB receptor activation in cerebellar granule cells: an in vitro model of preconditioning to stimulate intrinsic survival pathways in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The biochemistry of n-3 polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Isoflurane induced prolonged protection against cerebral ischemia in mice: a redox sensitive mechanism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

mRNA is an endogenous ligand for Toll-like receptor 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Statin effects on cholesterol micro-domains in brain plasma membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

'Ischemic tolerance' phenomenon found in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

IRAK-M is a negative regulator of Toll-like receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Suppressors of cytokine signaling and immunity

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Cooperation between toll-like receptor 2 and 4 in the brain of mice challenged with cell wall components derived from gram-negative and gram-positive bacteria

21 January 2018

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Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Circulating cell wall components derived from gram-negative, not gram-positive, bacteria cause a profound induction of the gene-encoding Toll-like receptor 2 in the CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Tristetraprolin and Its Family Members Can Promote the Cell-Free Deadenylation of AU-Rich Element-Containing mRNAs by Poly(A) Ribonuclease

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Sustained tolerance to lipopolysaccharide after liver ischemia-reperfusion injury

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Polyunsaturated fatty acids are potent neuroprotectors

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Reciprocal modulation of Toll-like receptor-4 signaling pathways involving MyD88 and phosphatidylinositol 3-kinase/AKT by saturated and polyunsaturated fatty acids

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

21 January 2018

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Minimally invasive surgery induces endotoxin-tolerance in the absence of detectable endotoxemia

21 January 2018

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An essential role of the NF-kappa B/Toll-like receptor pathway in induction of inflammatory and tissue-repair gene expression by necrotic cells

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide.

21 January 2018

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Mechanisms, challenges and opportunities in stroke

21 January 2018

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Thiopental inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappaB through suppression of kappaB kinase activity.

21 January 2018

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Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10--a role for IL-1 beta?

21 January 2018

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Identification of interleukin 1 receptor-associated kinase as a conserved component in the p75-neurotrophin receptor activation of nuclear factor-kappa B.

21 January 2018

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Toll-like receptors and innate immunity

21 January 2018

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Preventive antibacterial treatment improves the general medical and neurological outcome in a mouse model of stroke

21 January 2018

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Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA.

21 January 2018

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IFNs activate toll-like receptor gene expression in viral infections

21 January 2018

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Suppressive effects of volatile anesthetics on cytokine release in human peripheral blood mononuclear cells.

21 January 2018

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Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA.

21 January 2018

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Interleukin-10 and the interleukin-10 receptor

21 January 2018

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Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

21 January 2018

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Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells

21 January 2018

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Rapid tolerance to focal cerebral ischemia in rats is attenuated by adenosine A1 receptor antagonist

21 January 2018

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TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Alcohol, host defence and society

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Innate immunity: the missing link in neuroprotection and neurodegeneration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Ischemic tolerance in the rat neocortex following hypothermic preconditioning

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The interleukin-1 receptor/Toll-like receptor superfamily: signal transduction during inflammation and host defense.

21 January 2018

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Endotoxin Preconditioning in Pancreatic Ischemia/Reperfusion Injury

21 January 2018

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Role of interleukin-10 on hyporesponsiveness of endotoxin during surgery.

21 January 2018

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Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The chronic administration of docosahexaenoic acid reduces the spatial cognitive deficit following transient forebrain ischemia in rats

21 January 2018

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The extra domain A of fibronectin activates Toll-like receptor 4.

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Injury primes the innate immune system for enhanced Toll-like receptor reactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Rapid preconditioning neuroprotection following anoxia in hippocampal slices: role of the K+ ATP channel and protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Protective effects of the free radical scavengers, dimethyl sulfoxide and ethanol, in cerebral ischemia in gerbils

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Lipid rafts: bringing order to chaos

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Isoflurane pretreatment inhibits lipopolysaccharide-induced inflammation in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Gene expression analysis of spontaneously hypertensive rat cerebral cortex following transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Molecular insights on the cerebral innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Cytokine induction by 41.8 degrees C whole body hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Inflammatory gene expression in focal cortical brain ischemia: differences between rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Cell death releases endogenous adjuvants that selectively enhance immune surveillance of particulate antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Lipid rafts and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

IL-10 reduces rat brain injury following focal stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

IL-4-Stat6 signaling induces tristetraprolin expression and inhibits TNF-alpha production in mast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Transient neuronal depolarization induces tolerance to subsequent forebrain ischemia in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Ketamine inhibits endotoxin-induced shock in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Transient ischemic attacks before ischemic stroke: preconditioning the human brain? A multicenter magnetic resonance imaging study

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Endotoxin tolerance: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

RNA binding properties of the AU-rich element-binding recombinant Nup475/TIS11/tristetraprolin protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Relative cytokine and cytokine inhibitor production by mononuclear cells and neutrophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Neuroprotective effects of hyperthermic preconditioning on infarcted volume after middle cerebral artery occlusion in rats: role of adenosine receptors

21 January 2018

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https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Negative regulation of cytokine signaling influences inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Endotoxin induces a second window of protection in the rat heart as determined by using p-nitro-blue tetrazolium staining, cardiac troponin T release, and histology

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Negative regulation of toll-like receptor-mediated signaling by Tollip

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Gene suppression by tristetraprolin and release by the p38 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Late ischemic preconditioning of the myocardium alters the expression of genes involved in inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

Ischemic preconditioning reduces neurologic injury in a rat model of spinal cord ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000145666.68576.71

10.1097/01.WCB.0000145666.68576.71

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

11 August 2017

1004056328

0 references

1 reference