(Q35956222)

English

Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

Europe PubMed Central

Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

1 reference

based on heuristic

inferred from title

4

object named as

Laura P James

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Sandra S Mccullough

3

object named as

Sandra S McCullough

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

author name string

Jack A Hinson

1

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

Angela B Reid

2

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Europe PubMed Central

PubMed publication ID

11 August 2017

language of work or name

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publication date

1 October 2004

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Europe PubMed Central

PubMed publication ID

11 August 2017

Drug Metabolism Reviews

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Europe PubMed Central

PubMed publication ID

11 August 2017

36

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

3-4

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

805-822

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

N-acetyl-p-benzoquinone imine-induced changes in the energy metabolism in hepatocytes.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Role of metals in oxygen radical reactions

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Oxidative damage and tyrosine nitration from peroxynitrite

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Selective protein arylation and acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Selective protein covalent binding and target organ toxicity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

The spontaneous and enzymatic reaction of N-acetyl-p-benzoquinonimine with glutathione: A stopped-flow kinetic study

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Enzymatic activation of chemicals to toxic metabolites.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Structural characterization of the major covalent adduct formed in vitro between acetaminophen and bovine serum albumin

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Role of iron and glutathione redox cycle in acetaminophen-induced cytotoxicity to cultured rat hepatocytes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Acetaminophen-induced hepatotoxicity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Acetaminophen toxicity in mice lacking NADPH oxidase activity: role of peroxynitrite formation and mitochondrial oxidant stress

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Effect of N-acetylcysteine on acetaminophen toxicity in mice: relationship to reactive nitrogen and cytokine formation

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Immunochemical detection of oxidized proteins

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Vascular and hepatocellular peroxynitrite formation during acetaminophen toxicity: role of mitochondrial oxidant stress

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Role of lipid peroxidation as a mechanism of liver injury after acetaminophen overdose in mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Oxidative stress increases hepatocyte iNOS gene transcription and promoter activity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Superoxide dismutase and catalase protect cultured hepatocytes from the cytotoxicity of acetaminophen.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Biliary excretion of glutathione and glutathione disulfide in the rat. Regulation and response to oxidative stress

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

On the role of Ca2+ in the toxicity of alkylating and oxidizing quinone imines in isolated hepatocytes

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Benzoquinone inhibits the voltage-dependent induction of the mitochondrial permeability transition caused by redox-cycling naphthoquinones.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

The Treatment of Acetaminophen Poisoning

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Immunoblot analysis of protein containing 3-(cystein-S-yl)acetaminophen adducts in serum and subcellular liver fractions from acetaminophen-treated mice

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Bioactivation of halogenated hydrocarbons by cytochrome P4502E1.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Release of iron from ferritin and its role in oxygen radical toxicities

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Role of reactive oxygen species in cell toxicity

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Reversal of acetaminophen toxicity in isolated hamster hepatocytes by dithiothreitol.

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Further characterization of the events involved in mitochondrial Ca2+ release and pore formation by prooxidants

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

1 reference

https://api.crossref.org/works/10.1081%2FDMR-200033494

21 January 2018

Identifiers

10.1081/DMR-200033494

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 August 2017

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