(Q35959376)

11 August 2017

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title

Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation? (English)

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11 August 2017

Alan K Meeker

1

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11 August 2017

Pedram Argani

series ordinal

2

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11 August 2017

publication date

1 July 2004

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11 August 2017

number of pages

12

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Journal of Mammary Gland Biology and Neoplasia

inferred from page(s)

published in

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11 August 2017

volume

9

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11 August 2017

issue

3

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11 August 2017

page(s)

285-296

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https://scigraph.springernature.com/pub.10.1023/b:jomg.0000048775.04140.92

11 August 2017

exact match

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cites work

Telomerase activity and its inhibition in benign and malignant breast lesions

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12 December 2020

Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells

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12 December 2020

Telomerase activity and lymphovascular invasion in breast cancer.

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12 December 2020

Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.

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12 December 2020

Telomere dysfunction provokes regional amplification and deletion in cancer genomes.

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12 December 2020

Telomerase activity and survival of patients with node-positive breast cancer

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12 December 2020

The Stability of Broken Ends of Chromosomes in Zea Mays.

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12 December 2020

Stabilization of telomere length and karyotypic stability are directly correlated with the level of hTERT gene expression in primary fibroblasts

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12 December 2020

Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells

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12 December 2020

Reduced telomere DNA content is correlated with genomic instability and metastasis in invasive human breast carcinoma

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12 December 2020

Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation

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12 December 2020

Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization

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12 December 2020

Evidence of multifocality of telomere erosion in high-grade prostatic intraepithelial neoplasia (HPIN) and concurrent carcinoma.

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12 December 2020

Telomerase activity in normal and neoplastic breast.

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12 December 2020

Telomerase: a target for cancer therapeutics

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12 December 2020

The association between telomerase, histopathological parameters, and KI-67 expression in breast cancer.

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12 December 2020

Reduction of telomeric length and c-erbB-2 gene amplification in human breast cancer, fibroadenoma, and gynecomastia. Relationship to histologic grade and clinical parameters.

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12 December 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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12 December 2020

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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12 December 2020

Telomerase activity and genetic alterations in primary breast carcinomas

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12 December 2020

Treatment and prevention of intraepithelial neoplasia: an important target for accelerated new agent development

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12 December 2020

Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences

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12 December 2020

Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

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12 December 2020

Comparative genomic hybridization of ductal carcinoma in situ of the breast-evidence of multiple genetic pathways

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12 December 2020

Telomerase activity in ductal carcinoma in situ and invasive breast cancer

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12 December 2020

Telomere shortening is an early somatic DNA alteration in human prostate tumorigenesis.

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12 December 2020

Oxidative stress shortens telomeres

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12 December 2020

Telomere dysfunction and the initiation of genome instability.

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12 December 2020

Telomerase activity in human proliferative breast lesions

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12 December 2020

Cytogenetic clues to breast carcinogenesis

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12 December 2020

Structure and function of telomeres

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12 December 2020

Chromosomal instability in ulcerative colitis is related to telomere shortening

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12 December 2020

Telomerase is a highly sensitive and specific molecular marker in fine-needle aspirates of breast lesions

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12 December 2020

Loss of chromosomal integrity in human mammary epithelial cells subsequent to escape from senescence

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12 December 2020

Genetic instabilities in human cancers

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12 December 2020

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I

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12 December 2020

DNA repair and tumorigenesis: lessons from hereditary cancer syndromes

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12 December 2020

Telomerase activity and prognosis in primary breast cancers

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12 December 2020

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

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12 December 2020

Pooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions

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12 December 2020

Genetic and cytogenetic analyses of breast cancer yield different perspectives of a complex disease

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12 December 2020

BRCA1 and BRCA2 and the genetics of breast and ovarian cancer

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12 December 2020

Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast

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12 December 2020

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

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12 December 2020

A genetic model for colorectal tumorigenesis

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12 December 2020

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

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12 December 2020

Telomere length assessment in human archival tissues: combined telomere fluorescence in situ hybridization and immunostaining

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12 December 2020

Microsatellite instability in hereditary and sporadic breast cancers

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12 December 2020

Alternative lengthening of telomeres, telomerase, and cancer.

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12 December 2020

Haploinsufficiency of mTR results in defects in telomere elongation

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12 December 2020

Genetic changes associated with telomerase activity in breast cancer

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12 December 2020

Constitutive telomerase expression promotes mammary carcinomas in aging mice

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12 December 2020

Variable levels of chromosomal instability and mitotic spindle checkpoint defects in breast cancer

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12 December 2020

A critical role for telomeres in suppressing and facilitating carcinogenesis

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12 December 2020

Telomerase beyond telomeres

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12 December 2020

Quantitation of hTERT gene expression in sporadic breast tumors with a real-time reverse transcription-polymerase chain reaction assay

1 reference

12 December 2020

Telomerase activity as a marker of breast carcinoma in fine-needle aspirated samples

1 reference

12 December 2020

"Other" breast cancer susceptibility genes: searching for more holy grail

1 reference

12 December 2020

Aberrant expression of cell-cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability

1 reference

12 December 2020

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

12 December 2020

Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia

1 reference

12 December 2020

Widespread chromosomal abnormalities in high-grade ductal carcinoma in situ of the breast. Comparative genomic hybridization study of pure high-grade DCIS

1 reference

12 December 2020

[Telomere length in breast carcinoma of the young and aged]

1 reference

12 December 2020

Telomeric repeat fragment lengths are not correlated to histological grading in 85 breast cancers

1 reference

12 December 2020

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues

1 reference

12 December 2020

Telomerase activity in human breast tumors

1 reference

12 December 2020

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 reference

12 December 2020

Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome

1 reference

12 December 2020

Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

1 reference

12 December 2020

Inhibition of telomerase limits the growth of human cancer cells.

1 reference

12 December 2020

The age of cancer: telomeres, checkpoints, and longevity

1 reference

12 December 2020

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

12 December 2020

Telomerase activity correlates with tumor aggressiveness and reflects therapy effect in breast cancer

1 reference

12 December 2020

Careful histological confirmation and microdissection reveal telomerase activity in otherwise telomerase-negative breast cancers

1 reference

12 December 2020

The contribution of epigenetic changes to abnormal centrosomes and genomic instability in breast cancer

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12 December 2020

10.1023/B:JOMG.0000048775.04140.92

Identifiers

DOI

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Dimensions Publication ID

11 August 2017

1044021210

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