(Q35970685)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

3

1 reference

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30 December 2019

David G.I. Kingston

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1

Thota Ganesh

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

author name string

Rebecca C Guza

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Rudravajhala Ravindra

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Natasha Shanker

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

Ami S Lakdawala

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

James P Snyder

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

language of work or name

English

0 references

publication date

28 June 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

volume

101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

page(s)

10006-10011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

issue

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

Synthesis of novel C2-C3'N-linked macrocyclic taxoids by means of highly regioselective Heck macrocyclization

30 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Anticancer therapy with novel tubulin-interacting drugs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Refined structure of alpha beta-tubulin at 3.5 A resolution

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

The binding conformation of Taxol in beta-tubulin: a model based on electron crystallographic density

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Chemotherapy of breast cancer: are the taxanes going to change the natural history of breast cancer?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

2 October 2017

The taxanes: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Conformation of microtubule-bound paclitaxel determined by fluorescence spectroscopy and REDOR NMR.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

A common pharmacophore for cytotoxic natural products that stabilize microtubules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Taxanes in the treatment of breast cancer: a prodigy comes of age.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

High-resolution model of the microtubule

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Structure of the alpha beta tubulin dimer by electron crystallography

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Taxol: an antimitotic agent with a new mechanism of action

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Mechanism of action of taxol

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Probing the environment of tubulin-bound paclitaxel using fluorescent paclitaxel analogues.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

3'-(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Characterization of the taxol binding site on the microtubule. 2-(m-Azidobenzoyl)taxol photolabels a peptide (amino acids 217-231) of beta-tubulin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Promotion of microtubule assembly in vitro by taxol

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Synthesis of novel macrocyclic docetaxel analogues. Influence of their macrocyclic ring size on tubulin activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

The interaction of baccatin III with the taxol binding site of microtubules determined by a homogeneous assay with fluorescent taxoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Thermodynamics of ligand-induced assembly of tubulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Modeling the Interaction of Paclitaxel With β-Tubulin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Raf-1/bcl-2 phosphorylation: a step from microtubule damage to cell death.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=454156

Equilibrium Studies of a Fluorescent Paclitaxel Derivative Binding to Microtubules†

24 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0403459101

Conformationally restricted paclitaxel analogues: macrocyclic mimics of the "hydrophobic collapse" conformation

21 January 2018

1 reference

12 December 2020

A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone

1 reference

12 December 2020

Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed site

1 reference

12 December 2020

Synthesis and Biological Evaluation of Novel Macrocyclic Paclitaxel Analogues

1 reference

12 December 2020

Microtubule structure at 8 A resolution

1 reference

12 December 2020

The measurement of cooperative protein self-assembly by turbidity and other techniques

1 reference

12 December 2020

Studies With RP 56976 (Taxotere): A Semisynthetic Analogue of Taxol

1 reference

12 December 2020

Characterization of the Taxol Binding Site on the Microtubule

1 reference

12 December 2020

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0403459101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15226503%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

1 reference