(Q36012864)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Interactions between antiretrovirals and antineoplastic drug therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

main subject

anti-retroviral agent

0 references

author

Alice Tseng

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Tony Antoniou

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

Clinical Pharmacokinetics

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

111-145

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.2165/00003088-200544020-00001

7 January 2020

exact match

0 references

cites work

Cytochrome P-450-induced cytotoxicity of mitoxantrone by formation of electrophilic intermediates

1 reference

12 December 2020

Impact of tamoxifen on the pharmacokinetics and endocrine effects of the aromatase inhibitor letrozole in postmenopausal women with breast cancer

1 reference

12 December 2020

The pharmacokinetics of liposomal encapsulated daunorubicin are not modified by HAART in patients with HIV-associated Kaposi's sarcoma

1 reference

12 December 2020

In vitro metabolism of dexamethasone (DEX) in human liver and kidney: the involvement of CYP3A4 and CYP17 (17,20 LYASE) and molecular modelling studies

1 reference

12 December 2020

Pegylated-liposomal doxorubicin versus doxorubicin, bleomycin, and vincristine in the treatment of AIDS-related Kaposi's sarcoma: results of a randomized phase III clinical trial.

1 reference

12 December 2020

Grapefruit juice can increase the plasma concentrations of oral methylprednisolone

1 reference

12 December 2020

Anemia and erythropoiesis in patients with the acquired immunodeficiency syndrome (AIDS) and Kaposi sarcoma treated with zidovudine

1 reference

12 December 2020

Comparative binding affinities of tamoxifen, 4-hydroxytamoxifen, and desmethyltamoxifen for estrogen receptors isolated from human breast carcinoma: correlation with blood levels in patients with metastatic breast cancer

1 reference

12 December 2020

Variability in human cytochrome P450 paclitaxel metabolism

1 reference

12 December 2020

Increased teniposide clearance with concomitant anticonvulsant therapy

1 reference

12 December 2020

Metabolism of docetaxel by human cytochromes P450: interactions with paclitaxel and other antineoplastic drugs

1 reference

12 December 2020

Polyethylene glycol-liposomal doxorubicin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the management of AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

Phase II trial of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma: an Eastern Cooperative Oncology Group Trial (E1494).

1 reference

12 December 2020

Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.

1 reference

12 December 2020

Vinorelbine is an effective and safe drug for AIDS-related Kaposi's sarcoma: results of a phase II study

1 reference

12 December 2020

Clinical pharmacokinetics and metabolism of irinotecan (CPT-11).

1 reference

12 December 2020

Causes of death among HIV-infected patients in the era of highly active antiretroviral therapy, Bordeaux, France, 1998-1999.

1 reference

12 December 2020

The effects of menopause and hormone replacement therapies on prednisolone and erythromycin pharmacokinetics

1 reference

12 December 2020

Pretreatment H2 receptor antagonists that differ in P450 modulation activity: comparative effects on paclitaxel clearance rates and neutropenia

1 reference

12 December 2020

Protease inhibitors potentiate chemotherapy-induced neutropenia

1 reference

12 December 2020

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen

1 reference

12 December 2020

1 reference

12 December 2020

Pharmacokinetics of idarubicin (4-demethoxydaunorubicin; IMI-30; NSC 256439) following intravenous and oral administration in patients with advanced cancer

1 reference

12 December 2020

Association of CYP3A4 genotype with treatment-related leukemia

1 reference

12 December 2020

Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes

1 reference

12 December 2020

Metabolism and pharmacokinetics of oxazaphosphorines

1 reference

12 December 2020

Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes

1 reference

12 December 2020

Predicting drug interactions in vivo from experiments in vitro. Human studies with paclitaxel and ketoconazole

1 reference

12 December 2020

Rifampin-induced deterioration in steroid-dependent asthma

1 reference

12 December 2020

Peripheral neuropathy with nucleoside antiretrovirals: risk factors, incidence and management

1 reference

12 December 2020

Influence of phenobarbital induction on the enantioselective N-dechloroethylation of ifosfamide enantiomers in the rat

1 reference

12 December 2020

Pharmacokinetics of actinomycin 0 in patients with malignant melanoma

1 reference

12 December 2020

Paclitaxel pharmacokinetics and pharmacodynamics.

1 reference

12 December 2020

Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

1 reference

12 December 2020

Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel

1 reference

12 December 2020

Impact of highly active antiretroviral therapy in the treatment of HIV-infected patients with systemic non-Hodgkin's lymphoma.

1 reference

12 December 2020

Hepatic biotransformation of docetaxel (Taxotere) in vitro: involvement of the CYP3A subfamily in humans

1 reference

12 December 2020

1 reference

12 December 2020

Clinical pharmacokinetics of altretamine

1 reference

12 December 2020

Biotransformation of taxoids by human cytochromes P450: structure-activity relationship

1 reference

12 December 2020

Phase I AIDS Clinical Trials Group (075) study of adriamycin, bleomycin and vincristine chemotherapy with zidovudine in the treatment of AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer.

1 reference

12 December 2020

Pharmacokinetics and toxicity of mitomycin C in rodents, given alone, in combination, or after induction of microsomal drug metabolism

1 reference

12 December 2020

Phase II study of liposomal encapsulated daunorubicin in the treatment of AIDS-associated mucocutaneous Kaposi's sarcoma.

1 reference

12 December 2020

Management of drug interactions in patients with HIV.

1 reference

12 December 2020

Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles

1 reference

12 December 2020

Letrozole. A review of its use in postmenopausal women with advanced breast cancer

1 reference

12 December 2020

Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin

1 reference

12 December 2020

Species differences in the covalent binding of [14C]tamoxifen to liver microsomes and the forms of cytochrome P450 involved

1 reference

12 December 2020

Influence of co-medicated drugs on the biotransformation of thioTEPA to TEPA and thioTEPA-mercapturate

1 reference

12 December 2020

Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid.

1 reference

12 December 2020

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

1 reference

12 December 2020

Determination of tamoxifen and biologically active metabolites in human breast tumours and plasma

1 reference

12 December 2020

Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection

1 reference

12 December 2020

Low-dose compared with standard-dose m-BACOD chemotherapy for non-Hodgkin's lymphoma associated with human immunodeficiency virus infection. National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group

1 reference

12 December 2020

Topotecan: a new topoisomerase I inhibiting antineoplastic agent

1 reference

12 December 2020

Identification of human urinary mitoxantrone metabolites

1 reference

12 December 2020

Comparative in vitro cytotoxic effects of taxol and its major human metabolite 6 alpha-hydroxytaxol

1 reference

12 December 2020

Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial

1 reference

12 December 2020

The Metabolic Fate and Elimination of Streptozotocin

1 reference

12 December 2020

Clinical pharmacokinetics of commonly used anticancer drugs.

1 reference

12 December 2020

Phase IV study of liposomal daunorubicin (DaunoXome) in AIDS-related Kaposi sarcoma

1 reference

12 December 2020

Rifampin-induced nonresponsiveness of giant cell arteritis to prednisone treatment

1 reference

12 December 2020

Trends in causes of death among persons with acquired immunodeficiency syndrome in the era of highly active antiretroviral therapy, San Francisco, 1994-1998.

1 reference

12 December 2020

Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA.

1 reference

12 December 2020

The metabolism of chlorambucil

1 reference

12 December 2020

Ifosfamide stereoselective dichloroethylation and neurotoxicity

1 reference

12 December 2020

In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone

1 reference

12 December 2020

Concomitant cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy plus highly active antiretroviral therapy in patients with human immunodeficiency virus-related, non-Hodgkin lymphoma

1 reference

12 December 2020

Effect of Taxol on cytochrome P450 3A and acetaminophen toxicity in cultured rat hepatocytes: comparison to dexamethasone

1 reference

12 December 2020

Reduced incidence of Kaposi's sarcoma and of systemic non-hodgkin's lymphoma in HIV-infected individuals treated with highly active antiretroviral therapy.

1 reference

12 December 2020

Hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone and highly active antiretroviral therapy for patients with acquired immunodeficiency syndrome-related Burkitt lymphoma/leukemia

1 reference

12 December 2020

In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.

1 reference

12 December 2020

Individual variation in the activation and inactivation of metabolic pathways of cyclophosphamide

1 reference

12 December 2020

Daunorubicin metabolites in human urine

1 reference

12 December 2020

Stanford V regimen and concomitant HAART in 59 patients with Hodgkin disease and HIV infection.

1 reference

12 December 2020

AIDS Clinical Trials Group Study 094: a phase I/II trial of ABV chemotherapy with zidovudine and recombinant human GM-CSF in AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

Prolonged circulation time and enhanced accumulation in malignant exudates of doxorubicin encapsulated in polyethylene-glycol coated liposomes

1 reference

12 December 2020

Isolation, structural determination, and biological activity of 6 alpha-hydroxytaxol, the principal human metabolite of taxol

1 reference

12 December 2020

Multicenter trial of low-dose paclitaxel in patients with advanced AIDS-related Kaposi sarcoma.

1 reference

12 December 2020

Busulfan-glutathione conjugation catalyzed by human liver cytosolic glutathione S-transferases

1 reference

12 December 2020

In vitro and in vivo modulation of MDR1/P-glycoprotein in HIV-infected patients administered highly active antiretroviral therapy and liposomal doxorubicin

1 reference

12 December 2020

Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8

1 reference

12 December 2020

Aggravation of vincristine-induced neurotoxicity by itraconazole in the treatment of adult ALL.

1 reference

12 December 2020

Adriamycin-induced free radical formation in the perfused rat heart: implications for cardiotoxicity

1 reference

12 December 2020

Effect of tamoxifen on the enzymatic activity of human cytochrome CYP2B6.

1 reference

12 December 2020

Kinetics of cis-dichlorodiammineplatinum

1 reference

12 December 2020

HIV-1 protease inhibitors. A review for clinicians

1 reference

12 December 2020

Chemotherapy for human immunodeficiency virus-associated non-Hodgkin's lymphoma in combination with highly active antiretroviral therapy

1 reference

12 December 2020

Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide

1 reference

12 December 2020

Adriamycin metabolism in man. Evidence from urinary metabolites

1 reference

12 December 2020

Triethylenethiophosphoramide is a specific inhibitor of cytochrome P450 2B6: implications for cyclophosphamide metabolism

1 reference

12 December 2020

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.

1 reference

12 December 2020

Epidemiology of AIDS-related tumours in developed and developing countries

1 reference

12 December 2020

Comparative pharmacokinetics of chlorambucil and melphalan in man

1 reference

12 December 2020

Metabolism of tamoxifen by recombinant human cytochrome P450 enzymes: formation of the 4-hydroxy, 4'-hydroxy and N-desmethyl metabolites and isomerization of trans-4-hydroxytamoxifen.

1 reference

12 December 2020

Regioselective metabolism of taxoids by human CYP3A4 and 2C8: structure-activity relationship

1 reference

12 December 2020

Pharmacokinetics and metabolism of epidoxorubicin and doxorubicin in humans

1 reference

12 December 2020

Modulation of irinotecan metabolism by ketoconazole

1 reference

12 December 2020

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

12 December 2020

Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction

1 reference

12 December 2020

The disposition of saquinavir in normal and P-glycoprotein deficient mice, rats, and in cultured cells.

1 reference

12 December 2020

Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy

1 reference

12 December 2020

Streptozocin: a review of its pharmacology, efficacy, and toxicity

1 reference

12 December 2020

Pharmacokinetics of 4'-epi-doxorubicin in man

1 reference

12 December 2020

Stereoselective metabolism of ifosfamide by human P-450s 3A4 and 2B6. Favorable metabolic properties of R-enantiomer

1 reference

12 December 2020

Taxol metabolism. Isolation and identification of three major metabolites of taxol in rat bile

1 reference

12 December 2020

The cytochrome P450 3A4 inhibitor itraconazole markedly increases the plasma concentrations of dexamethasone and enhances its adrenal-suppressant effect

1 reference

12 December 2020

Effect of idarubicin and epirubicin on in vitro polymorphonuclear function: diminished superoxide radical formation compared to their parent compounds daunorubicin and doxorubicin

1 reference

12 December 2020

Population pharmacokinetics and pharmacodynamics of pegylated-liposomal doxorubicin in patients with AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

A monohydroxylated metabolite of tamoxifen with potent antioestrogenic activity

1 reference

12 December 2020

Infusional cyclophosphamide, doxorubicin and etoposide in HIV-related non-Hodgkin's lymphoma: a follow-up report of a highly active regimen.

1 reference

12 December 2020

The effect of grapefruit juice on cyclosporine and prednisone metabolism in transplant patients

1 reference

12 December 2020

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

12 December 2020

Pilot trial of infusional cyclophosphamide, doxorubicin, and etoposide plus didanosine and filgrastim in patients with human immunodeficiency virus-associated non-Hodgkin's lymphoma

1 reference

12 December 2020

Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes

1 reference

12 December 2020

Comparative mammalian metabolism of adriamycin and daunorubicin

1 reference

12 December 2020

Screening for inhibitory effects of antineoplastic agents on CYP3A4 in human liver microsomes.

1 reference

12 December 2020

Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes

1 reference

12 December 2020

Improved survival in HIV-related Hodgkin's lymphoma since the introduction of highly active antiretroviral therapy

1 reference

12 December 2020

Epidemiology of non-Hodgkin lymphomas and other haemolymphopoietic neoplasms in people with AIDS.

1 reference

12 December 2020

Enzymology of mitomycin C metabolic activation in tumour tissue: implications for enzyme-directed bioreductive drug development

1 reference

12 December 2020

Effect of cimetidine, probenecid, and ketoconazole on the distribution, biliary secretion, and metabolism of [3H]taxol in the Sprague-Dawley rat.

1 reference

12 December 2020

Influence of phenytoin on the disposition of irinotecan: a case report

1 reference

12 December 2020

Non-Hodgkin lymphoma in HIV-infected patients in the era of highly active antiretroviral therapy

1 reference

12 December 2020

Droloxifene, a new anti-oestrogen in postmenopausal advanced breast cancer: preliminary results of a double-blind dose-finding phase II trial

1 reference

12 December 2020

Modulation of thiotepa antitumor activity in vivo by alteration of liver cytochrome P450-catalyzed drug metabolism.

1 reference

12 December 2020

Drug interaction potential with inhibitors of HIV protease.

1 reference

12 December 2020

Reversible and irreversible inhibition of CYP3A enzymes by tamoxifen and metabolites

1 reference

12 December 2020

Clinical pharmacokinetics of oral CCNU (lomustine)

1 reference

12 December 2020

Effect of itraconazole on the pharmacokinetics of prednisolone and methylprednisolone and cortisol secretion in healthy subjects

1 reference

12 December 2020

Clinical pharmacology of mitoxantrone.

1 reference

12 December 2020

The analysis of ifosfamide and its metabolites (review).

1 reference

12 December 2020

Ritonavir induces P-glycoprotein expression, multidrug resistance-associated protein (MRP1) expression, and drug transporter-mediated activity in a human intestinal cell line

1 reference

12 December 2020

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

1 reference

12 December 2020

A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes.

1 reference

12 December 2020

Incidence and trends in Kaposi's sarcoma in the era of effective antiretroviral therapy

1 reference

12 December 2020

Variable contribution of cytochromes P450 2D6, 2C9 and 3A4 to the 4-hydroxylation of tamoxifen by human liver microsomes

1 reference

12 December 2020

Causes of death among women with human immunodeficiency virus infection in the era of combination antiretroviral therapy

1 reference

12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

12 December 2020

Pharmacokinetic study of cis-dichlorodiammineplatinum(II) (DDP) in the beagle dog: thermodynamic and kinetic behavior of DDP in a biologic millieu

1 reference

12 December 2020

Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes

1 reference

12 December 2020

Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450

1 reference

12 December 2020

Comparison of the properties of metabolites of CCNU

1 reference

12 December 2020

Randomized comparative trial of pegylated liposomal doxorubicin versus bleomycin and vincristine in the treatment of AIDS-related Kaposi's sarcoma. International Pegylated Liposomal Doxorubicin Study Group

1 reference

12 December 2020

HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833.

1 reference

12 December 2020

Potentiation of vincristine toxicity by itraconazole in children with lymphoid malignancies.

1 reference

12 December 2020

Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded phi X174 DNA.

1 reference

12 December 2020

Response to liposomal doxorubicin and clinical outcome of HIV-1-infected patients with Kaposi's sarcoma receiving highly active antiretroviral therapy

1 reference

12 December 2020

An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane

1 reference

12 December 2020

Drug interactions in HIV-positive patients initiated on protease inhibitor therapy

1 reference

12 December 2020

The pharmacological role of P-glycoprotein in the intestinal epithelium.

1 reference

12 December 2020

Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin

1 reference

12 December 2020

Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors

1 reference

12 December 2020

The effect of an individual's cytochrome CYP3A4 activity on docetaxel clearance

1 reference

12 December 2020

Combined antineoplastic and antiretroviral therapy for patients with Hodgkin's disease and human immunodeficiency virus infection. A prospective study of 17 patients. The Italian Cooperative Group on AIDS and Tumors (GICAT).

1 reference

12 December 2020

Current perspectives on the clinical experience, pharmacology, and continued development of the camptothecins.

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation

1 reference

12 December 2020

Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation

1 reference

12 December 2020

Pharmacokinetics and toxicity of two schedules of high dose epirubicin

1 reference

12 December 2020

Modulation of oral bioavailability of anticancer drugs: from mouse to man.

1 reference

12 December 2020

Pharmacodynamics of tamoxifen and its 4-hydroxy and N-desmethyl metabolites: activation of caspases and induction of apoptosis in rat mammary tumors and in human breast cancer cell lines.

1 reference

12 December 2020

Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1

1 reference

12 December 2020

Peroxidase-catalyzed metabolism of etoposide (VP-16-213) and covalent binding of reactive intermediates to cellular macromolecules

1 reference

12 December 2020

Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma

1 reference

12 December 2020

Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromatase

1 reference

12 December 2020

Evidence for oxidative activation of mitoxantrone in human, pig, and rat

1 reference

12 December 2020

The effect of dexamethasone on the pharmacokinetics of triazolam.

1 reference

12 December 2020

Kinetics of intravenous melphalan

1 reference

12 December 2020

Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response

1 reference

12 December 2020

Modulation of glucuronidation of SN-38, the active metabolite of irinotecan, by valproic acid and phenobarbital

1 reference

12 December 2020

Cytochrome P450-inducing antiepileptics increase the clearance of vincristine in patients with brain tumors

1 reference

12 December 2020

Urinary and fecal excretion of topotecan in patients with malignant solid tumours

1 reference

12 December 2020

Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters

1 reference

12 December 2020

Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors

1 reference

12 December 2020

Human immunodeficiency virus-related non-Hodgkin lymphoma: activity of infusional cyclophosphamide, doxorubicin, and etoposide as second-line chemotherapy in 40 patients

1 reference

12 December 2020

Pharmacokinetics and metabolism of vinblastine in humans

1 reference

12 December 2020

Bilary disposition of adriamycin

1 reference

12 December 2020

Review of the comparative pharmacology and clinical activity of cisplatin and carboplatin

1 reference

12 December 2020

Bleomycin inhibits hepatic mixed function oxidation

1 reference

12 December 2020

Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation

1 reference

12 December 2020

Pharmacokinetics of mitomycin C in humans

1 reference

12 December 2020

Pharmacokinetics and metabolism of formestane in breast cancer patients

1 reference

12 December 2020

Isolation and structural confirmation of N-desmethyl topotecan, a metabolite of topotecan.

1 reference

12 December 2020

Cytochrome P-450-mediated O-demethylation: a route in the metabolic activation of etoposide (VP-16-213)

1 reference

12 December 2020

Metabolism of taxol by human and rat liver in vitro: a screen for drug interactions and interspecies differences.

1 reference

12 December 2020

Plasma pharmacokinetics of adriamycin and its metabolites in humans with normal hepatic and renal function

1 reference

12 December 2020

Differential activation of cyclophosphamide and ifosphamide by cytochromes P-450 2B and 3A in human liver microsomes

1 reference

12 December 2020

Identification of tamoxifen-DNA adducts in the endometrium of women treated with tamoxifen.

1 reference

12 December 2020

Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir

1 reference

12 December 2020

Saquinavir enhances the mucosal toxicity of infusional cyclophosphamide, doxorubicin, and etoposide in patients with HIV-associated non-Hodgkin's lymphoma

1 reference

12 December 2020

Paclitaxel is safe and effective in the treatment of advanced AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions

1 reference

12 December 2020

Plasma concentrations and effects of oral methylprednisolone are considerably increased by itraconazole

1 reference

12 December 2020

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

1 reference

12 December 2020

Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations

1 reference

12 December 2020

Effects of St. John's wort on irinotecan metabolism

1 reference

12 December 2020

Phase I study of oral mitomycin C

1 reference

12 December 2020

Phase I study of paclitaxel in patients with recurrent malignant glioma: a North American Brain Tumor Consortium report.

1 reference

12 December 2020

Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers

1 reference

12 December 2020

Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines

1 reference

12 December 2020

Induction of cytochrome P4503A by taxol in primary cultures of human hepatocytes.

1 reference

12 December 2020

O-glucuronidation, a newly identified metabolic pathway for topotecan and N-desmethyl topotecan

1 reference

12 December 2020

Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture

1 reference

12 December 2020

The role of reductive and oxidative metabolism in the toxicity of mitoxantrone, adriamycin and menadione in human liver derived Hep G2 hepatoma cells

1 reference

12 December 2020

Effect of highly active antiretroviral therapy (HAART) on pharmacokinetics and pharmacodynamics of doxorubicin in patients with HIV-associated non-Hodgkin's lymphoma.

1 reference

12 December 2020

Influence of highly active anti-retroviral therapy on response to treatment and survival in patients with acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma treated with cyclophosphamide, hydroxydoxorubicin, vincristine and prednisone

1 reference

12 December 2020

Potential interaction of antiretroviral therapy with paclitaxel in patients with AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

The effect of cyclophosphamide with and without dexamethasone on cytochrome P450 3A4 and 2B6 in human hepatocytes

1 reference

12 December 2020

Human cytochrome P450 metabolism of teniposide and etoposide

1 reference

12 December 2020

Mutual inhibition between quinine and etoposide by human liver microsomes. Evidence for cytochrome P4503A4 involvement in their major metabolic pathways

1 reference

12 December 2020

Detoxication of vinca alkaloids by human P450 CYP3A4-mediated metabolism: implications for the development of drug resistance

1 reference

12 December 2020

Potential drug interaction with paclitaxel and highly active antiretroviral therapy in two patients with AIDS-associated Kaposi sarcoma

1 reference

12 December 2020

Idarubicin metabolism and pharmacokinetics after intravenous and oral administration in cancer patients: a crossover study

1 reference

12 December 2020

Renal handling of cis-diamminedichloroplatinum(II)

1 reference

12 December 2020

Paclitaxel in the treatment of human immunodeficiency virus 1-associated Kaposi's sarcoma--drug-drug interactions with protease inhibitors and a nonnucleoside reverse transcriptase inhibitor: a case report study

1 reference

12 December 2020

CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes

1 reference

12 December 2020

In vitro and in vivo evidence for the formation of methyl radical from procarbazine: a spin-trapping study.

1 reference

12 December 2020

Cytochrome P450 2B1-mediated one-electron reduction of adriamycin: a study with rat liver microsomes and purified enzymes

1 reference

12 December 2020

Randomized phase III trial of liposomal daunorubicin versus doxorubicin, bleomycin, and vincristine in AIDS-related Kaposi's sarcoma

1 reference

12 December 2020

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

1 reference

12 December 2020

Molecular and pharmacokinetic evaluation of rat hepatic and gastrointestinal cytochrome p450 induction by tamoxifen

1 reference

12 December 2020

Randomised placebo-controlled trial of ritonavir in advanced HIV-1 disease. The Advanced HIV Disease Ritonavir Study Group

1 reference

12 December 2020

Increased activity of CYP3A enzyme in primary cultures of rat hepatocytes treated with docetaxel: comparative evaluation with paclitaxel

1 reference

12 December 2020

A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro

1 reference

12 December 2020

Pharmacokinetics and metabolism of the anti-oestrogen droloxifene in female human subjects

1 reference

12 December 2020

CYP3A4 is mainly responsibile for the metabolism of a new vinca alkaloid, vinorelbine, in human liver microsomes

1 reference

12 December 2020

Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells

1 reference

12 December 2020

Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively

1 reference

12 December 2020

Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.

1 reference

12 December 2020

Low systemic exposure of oral docetaxel in mice resulting from extensive first-pass metabolism is boosted by ritonavir

1 reference

12 December 2020

Biliary excretion of a glutathione conjugate of busulfan and 1,4-diiodobutane in the rat

1 reference

12 December 2020

Tamoxifen and metabolites in MCF7 cells: correlation between binding to estrogen receptor and inhibition of cell growth.

1 reference

12 December 2020

Phenytoin alters the disposition of topotecan and N-desmethyl topotecan in a patient with medulloblastoma.

1 reference

12 December 2020

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

1 reference

12 December 2020

Stanford V and radiotherapy for locally extensive and advanced Hodgkin's disease: mature results of a prospective clinical trial

1 reference

12 December 2020

Pharmacokinetics of droloxifene and its metabolites in breast cancer patients

1 reference

12 December 2020

Etoposide and antimetabolite pharmacology in patients who develop secondary acute myeloid leukemia

1 reference

12 December 2020

Cytotoxicity of mitomycin C and adriamycin in freshly isolated rat hepatocytes: the role of cytochrome P450

1 reference

12 December 2020

Lack of pharmacokinetic and pharmacodynamic interactions between ketoconazole and prednisolone

1 reference

12 December 2020

Itraconazole can increase systemic exposure to busulfan in patients given bone marrow transplantation. GITMO (Gruppo Italiano Trapianto di Midollo Osseo)

1 reference

12 December 2020

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen.

1 reference

12 December 2020

The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone

1 reference

12 December 2020

Tyrosinase-induced free radical formation from VP-16,213: relationship to cytotoxicity

1 reference

12 December 2020

Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion

1 reference

12 December 2020

Drug interactions in patients infected with human immunodeficiency virus

1 reference

12 December 2020

10.2165/00003088-200544020-00001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15656694%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

7 January 2020

1045728086

0 references

Fatcat ID

release_54rfc3se2racbbioqzcxnu6ay4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/54rfc3se2racbbioqzcxnu6ay4

24 November 2022

mapped directly with Wikidata item

1 reference