(Q36016964)

11 August 2017

Zn2+-Aβ40 complexes form metastable quasi-spherical oligomers that are cytotoxic to cultured hippocampal neurons (English)

1 reference

11 August 2017

0 references

Inna Solomonov

1

1 reference

11 August 2017

Eduard Korkotian

2

1 reference

11 August 2017

Benjamin Born

3

1 reference

11 August 2017

Yishay Feldman

4

1 reference

11 August 2017

Arkady Bitler

5

1 reference

11 August 2017

Farid Rahimi

6

1 reference

11 August 2017

Huiyuan Li

7

1 reference

11 August 2017

Gal Bitan

8

1 reference

11 August 2017

Irit Sagi

9

1 reference

11 August 2017

language of work or name

English

0 references

publication date

23 April 2012

1 reference

Journal of Biological Chemistry

11 August 2017

1 reference

11 August 2017

287

1 reference

11 August 2017

24

1 reference

11 August 2017

20555-20564

1 reference

describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3370240/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Effect of zinc binding on β-amyloid structure and dynamics: implications for Aβ aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Solid-state NMR studies of amyloid fibril structure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Zinc ions promote Alzheimer Abeta aggregation via population shift of polymorphic states

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Structure-neurotoxicity relationships of amyloid beta-protein oligomers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Structure-function relationships of pre-fibrillar protein assemblies in Alzheimer's disease and related disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

A network dysfunction perspective on neurodegenerative diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Neural synchrony in brain disorders: relevance for cognitive dysfunctions and pathophysiology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

The neurobiology of zinc in health and disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

The secretases of Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

In vitro characterization of conditions for amyloid-beta peptide oligomerization and fibrillogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

A unifying hypothesis of Alzheimer's disease. IV. Causation and sequence of events

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Alzheimer's amyloid fibrils: structure and assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Morphological analysis of dendritic spine development in primary cultures of hippocampal neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Abeta(1-40) forms five distinct amyloid structures whose beta-sheet contents and fibril stabilities are correlated

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Copper, iron and zinc in Alzheimer's disease senile plaques

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Rapid induction of Alzheimer A beta amyloid formation by zinc.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Amyloid plaques arise from zinc-enriched cortical layers in APP/PS1 transgenic mice and are paradoxically enlarged with dietary zinc deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Zinc-amyloid beta interactions on a millisecond time-scale stabilize non-fibrillar Alzheimer-related species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Zinc-induced Alzheimer's Abeta1-40 aggregation is mediated by conformational factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Elucidation of primary structure elements controlling early amyloid beta-protein oligomerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Evidence of fibril-like β-sheet structures in a neurotoxic amyloid intermediate of Alzheimer's β-amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Early development of neuronal activity in the primate hippocampus in utero.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

The common architecture of cross-beta amyloid

23 September 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3370240

23 September 2018

https://api.crossref.org/works/10.1074%2FJBC.M112.344036

Beta-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22528492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective destabilization of soluble amyloid β oligomers by divalent metal ions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22528492

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.344036

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22528492

1 reference