(Q36019822)

11 August 2017

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title

Second-generation antihistamines: actions and efficacy in the management of allergic disorders (English)

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11 August 2017

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Larry K Golightly

1

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11 August 2017

Leon S Greos

series ordinal

2

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11 August 2017

publication date

1 January 2005

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11 August 2017

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11 August 2017

volume

65

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11 August 2017

issue

3

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11 August 2017

page(s)

341-384

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Brompheniramine, loratadine, and placebo in allergic rhinitis: a placebo-controlled comparative clinical trial

11 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003495-200565030-00004

Effects of Fexofenadine, Diphenhydramine, and Alcohol on Driving Performance: A Randomized, Placebo-Controlled Trial in the Iowa Driving Simulator

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.2165%2F00003495-200565030-00004

Cetirizine treatment of allergic cough in children with pollen allergy

21 January 2018

1 reference

12 December 2020

Adverse ocular drug reactions recently identified by the National Registry of Drug-Induced Ocular Side Effects

1 reference

12 December 2020

A single-center, randomized, double-blind, placebo-controlled, crossover investigation of the effects of fexofenadine hydrochloride 180 mg alone and with alcohol, with hydroxyzine hydrochloride 50 mg as a positive internal control, on aspects of cog

1 reference

12 December 2020

Effect of cetirizine on cutaneous reactions to PAF, kallikrein and serum in patients with chronic urticaria

1 reference

12 December 2020

Burn wound itch control using H1 and H2 antagonists

1 reference

12 December 2020

Validation of the standardized version of the Rhinoconjunctivitis Quality of Life Questionnaire.

1 reference

12 December 2020

Molecular events in allergic inflammation: experimental models and possible modulation

1 reference

12 December 2020

Clinical pharmacology of new histamine H1 receptor antagonists

1 reference

12 December 2020

Eosinophil infiltration: Effects of H1 antihistamines

1 reference

12 December 2020

FDA approves OTC Claritin

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of cetirizine in infants and toddlers

1 reference

12 December 2020

Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic

1 reference

12 December 2020

The use of newer asthma and allergy medications during pregnancy. The American College of Obstetricians and Gynecologists (ACOG) and The American College of Allergy, Asthma and Immunology (ACAAI)

1 reference

12 December 2020

In vivo and in vitro effects of antihistamines on mast cell mediator release: a potentially important property in the treatment of allergic disease

1 reference

12 December 2020

Mite-antigen induced immediate reactions in atopic dermatitis are inhibited by daily administration of fexofenadine

1 reference

12 December 2020

Non-cardiac adverse effects of antihistamines (H1-receptor antagonists).

1 reference

12 December 2020

Desloratadine: an update of its efficacy in the management of allergic disorders

1 reference

12 December 2020

Effects of loratadine on cytosolic Ca2+ levels and leukotriene release: novel mechanisms of action independent of the anti-histamine activity

1 reference

12 December 2020

Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine

1 reference

12 December 2020

Comparison of five new antihistamines (H1-receptor antagonists) in patients with allergic rhinitis using nasal provocation studies and skin tests

1 reference

12 December 2020

Reduction of soluble ICAM-1 levels in nasal secretion by H1-blockers in seasonal allergic rhinitis

1 reference

12 December 2020

Mechanism of the cardiotoxic actions of terfenadine

1 reference

12 December 2020

The pharmacokinetics of loratadine in normal geriatric volunteers

1 reference

12 December 2020

Influence of food on the oral bioavailability of loratadine and pseudoephedrine from extended-release tablets in healthy volunteers

1 reference

12 December 2020

A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis.

1 reference

12 December 2020

Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block

1 reference

12 December 2020

Prospective controlled study of hydroxyzine and cetirizine in pregnancy

1 reference

12 December 2020

Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine

1 reference

12 December 2020

1 reference

12 December 2020

Histamine and tryptase in nasal lavage fluid after allergen challenge: effect of 1 week of pretreatment with intranasal azelastine or systemic cetirizine.

1 reference

12 December 2020

Pregnancy outcome following first trimester exposure to antihistamines: meta-analysis

1 reference

12 December 2020

Mutational analysis of the antagonist-binding site of the histamine H(1) receptor

1 reference

12 December 2020

Cetirizine reduces cytokines and inflammatory cells in children with perennial allergic rhinitis.

1 reference

12 December 2020

A pharmacokinetic-pharmacodynamic modelling of the antihistaminic (H1) effects of cetirizine

1 reference

12 December 2020

Treatment of hay fever with loratadine--a new non-sedating antihistamine

1 reference

12 December 2020

Comparative study of acute effects of single doses of fexofenadine, olopatadine, d-chlorpheniramine and placebo on psychomotor function in healthy volunteers

1 reference

12 December 2020

Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989‐94

1 reference

12 December 2020

Pharmacokinetics of cetirizine in chronic hemodialysis patients: multiple-dose study

1 reference

12 December 2020

Arrhythmogenic mechanisms of non-sedating antihistamines

1 reference

12 December 2020

An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers

1 reference

12 December 2020

1 reference

12 December 2020

Clinical assessment of antihistamines in rhinitis

1 reference

12 December 2020

Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving

1 reference

12 December 2020

Effect of cetirizine on bronchial hyperresponsiveness in patients with seasonal allergic rhinitis and asthma

1 reference

12 December 2020

Comparison of the efficacy and safety of loratadine, terfenadine, and placebo in the treatment of seasonal allergic rhinitis

1 reference

12 December 2020

Link between patient preferences and treatment outcomes in seasonal allergic rhinitis: an empiric investigation

1 reference

12 December 2020

Early treatment of perennial rhinitis with budesonide or cetirizine and its effect on long-term outcome

1 reference

12 December 2020

Fixed drug eruption due to loratadine

1 reference

12 December 2020

Upper gastrointestinal obstruction associated with Claritin-D 24 Hour Extended Release tablets

1 reference

12 December 2020

Fexofenadine does not affect omeprazole pharmacokinetics: both are putative P-glycoprotein substrates

1 reference

12 December 2020

Comparison of the central nervous system effects produced by six H1-receptor antagonists

1 reference

12 December 2020

Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis

1 reference

12 December 2020

The risk of esophageal obstruction associated with an anti-allergy medication (Claritin-D 24-Hour--original formulation).

1 reference

12 December 2020

Do antihistamines have a role in asthma therapy?

1 reference

12 December 2020

A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.

1 reference

12 December 2020

Inhibitory activity of loratadine and descarboxyethoxyloratadine on histamine-induced activation of endothelial cells

1 reference

12 December 2020

Cetirizine exerts anti-inflammatory effects on human neutrophils

1 reference

12 December 2020

Diagnosis and management of rhinitis: complete guidelines of the Joint Task Force on Practice Parameters in Allergy, Asthma and Immunology. American Academy of Allergy, Asthma, and Immunology

1 reference

12 December 2020

1 reference

12 December 2020

The advantages for an H1 antihistamine of a low volume of distribution

1 reference

12 December 2020

Desloratadine reduces allergen challenge-induced mucinous secretion and plasma exudation in allergic rhinitis

1 reference

12 December 2020

Comparative onset of action and symptom relief with cetirizine, loratadine, or placebo in an environmental exposure unit in subjects with seasonal allergic rhinitis: confirmation of a test system

1 reference

12 December 2020

Management of urticaria: a consensus report

1 reference

12 December 2020

Appraisal of the validity of histamine-induced wheal and flare to predict the clinical efficacy of antihistamines

1 reference

12 December 2020

Impact of interventions designed to increase market share and prescribing of fexofenadine at HMOs

1 reference

12 December 2020

Double-blind study of cetirizine in atopic eczema in children

1 reference

12 December 2020

Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study

1 reference

12 December 2020

Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin

1 reference

12 December 2020

Cetirizine inhibits bradykinin-induced cutaneous wheal and flare in atopic and healthy subjects

1 reference

12 December 2020

Antihistamines in the treatment of asthma

1 reference

12 December 2020

Initial and steady-state effects of diphenhydramine and loratadine on sedation, cognition, mood, and psychomotor performance

1 reference

12 December 2020

Comparative activity of cetirizine and mizolastine on histamine-induced skin wheal and flare responses at 24 h.

1 reference

12 December 2020

The effect of rifampin administration on the disposition of fexofenadine

1 reference

12 December 2020

QT lengthening and arrhythmias associated with fexofenadine

1 reference

12 December 2020

Loratadine. A preliminary review of its pharmacodynamic properties and therapeutic efficacy

1 reference

12 December 2020

Efficacy and safety of fexofenadine hydrochloride for treatment of seasonal allergic rhinitis

1 reference

12 December 2020

Dose proportionality and comparison of single and multiple dose pharmacokinetics of fexofenadine (MDL 16455) and its enantiomers in healthy male volunteers

1 reference

12 December 2020

Receptor effects of cetirizine

1 reference

12 December 2020

A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects

1 reference

12 December 2020

Rhinasthma: a new specific QoL questionnaire for patients with rhinitis and asthma.

1 reference

12 December 2020

Preclinical in vitro cardiac electrophysiology: a method of predicting arrhythmogenic potential of antihistamines in humans?

1 reference

12 December 2020

Studies on the central effects of the H1-antagonist, loratadine

1 reference

12 December 2020

Effects of a single dose of loratadine on flying ability under conditions of simulated cabin pressure

1 reference

12 December 2020

Cetirizine: a review of its use in allergic disorders

1 reference

12 December 2020

Nasal effect of cetirizine and loratadine at 24 hours in patients with allergic rhinitis.

1 reference

12 December 2020

Severe hepatotoxicity after application of desloratadine and fluconazole

1 reference

12 December 2020

Loratadine in the treatment of urticaria

1 reference

12 December 2020

Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression

1 reference

12 December 2020

Absorption, distribution, metabolism and excretion of [14C]levocetirizine, the R enantiomer of cetirizine, in healthy volunteers

1 reference

12 December 2020

Is antihistamine (H1-receptor antagonist) therapy useful in clinical asthma?

1 reference

12 December 2020

Effect of loratadine on human eosinophil function in vitro

1 reference

12 December 2020

Cetirizine modulates adhesion molecule expression in a double-blind controlled study conducted in psoriatic patients.

1 reference

12 December 2020

Double-blind comparison of cetirizine and loratadine in children ages 2 to 6 years with perennial allergic rhinitis.

1 reference

12 December 2020

Effect of food on the bioavailability of fexofenadine hydrochloride (MDL 16455A).

1 reference

12 December 2020

Cutaneous antihistaminic action of cetirizine and dose-related EEG concomitants of sedation in man

1 reference

12 December 2020

Double-blind multicenter study on the efficacy and tolerability of cetirizine compared with oxatomide in chronic idiopathic urticaria in preschool children

1 reference

12 December 2020

Treatment of urticaria. An evidence-based evaluation of antihistamines

1 reference

12 December 2020

Probable interaction between cetirizine and acenocoumarol

1 reference

12 December 2020

Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma

1 reference

12 December 2020

The clinical pharmacology of fexofenadine in children

1 reference

12 December 2020

Effect of race and sex on single and multiple dose pharmacokinetics of desloratadine

1 reference

12 December 2020

Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness

1 reference

12 December 2020

Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: a double-blind comparison with crossover treatment of nonresponders.

1 reference

12 December 2020

Clinical reports: Antiinflammatory properties of cetirizine in a human contact dermatitis model: Clinical evaluation of patch tests is not hampered by antihistamines

1 reference

12 December 2020

The antiemetic effect of cetirizine during pregnancy

1 reference

12 December 2020

Fexofenadine decreases sensitivity to and montelukast improves recovery from inhaled mannitol

1 reference

12 December 2020

Intranasal steroids and the risk of emergency department visits for asthma

1 reference

12 December 2020

Safety of cetirizine in infants 6 to 11 months of age: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Pharmacokinetics and dose proportionality of loratadine

1 reference

12 December 2020

Further improvement of quality of life by cetirizine in perennial allergic rhinitis as a function of treatment duration.

1 reference

12 December 2020

Loratadine and desethoxylcarbonyl-loratadine inhibit the immunological release of mediators from human Fc epsilon RI+ cells

1 reference

12 December 2020

Assessment of urticaria and angio-oedema

1 reference

12 December 2020

A double-blind, placebo-controlled trial of fexofenadine HCl in the treatment of chronic idiopathic urticaria

1 reference

12 December 2020

Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial

1 reference

12 December 2020

Electrophysiological effects of cetirizine, astemizole and D-sotalol in a canine model of long QT syndrome.

1 reference

12 December 2020

Fexofenadine transport in Caco-2 cells: inhibition with verapamil and ritonavir

1 reference

12 December 2020

Molecular basis for the lack of HERG K+ channel block-related cardiotoxicity by the H1 receptor blocker cetirizine compared with other second-generation antihistamines

1 reference

12 December 2020

Inhibitory effect of cetirizine 2HCl on eosinophil migration in vivo

1 reference

12 December 2020

The effect of cetirizine on the integrin-dependent respiratory burst of normodense eosinophils

1 reference

12 December 2020

P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists

1 reference

12 December 2020

Montelukast as an adjuvant to mainstay therapies in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Subfulminant liver failure and severe hepatotoxicity caused by loratadine use

1 reference

12 December 2020

Fluticasone propionate aqueous nasal spray compared with oral loratadine in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Lack of clinically relevant interaction between desloratadine and erythromycin

1 reference

12 December 2020

The antihistamine fexofenadine does not affect I(Kr) currents in a case report of drug-induced cardiac arrhythmia

1 reference

12 December 2020

Desloratadine demonstrates dose proportionality in healthy adults after single doses

1 reference

12 December 2020

Drug interactions with the nonsedating antihistamines.

1 reference

12 December 2020

Effect of cetirizine on the inflammatory cells in mosquito bites

1 reference

12 December 2020

Effect of fexofenadine on eosinophil-induced changes in epithelial permeability and cytokine release from nasal epithelial cells of patients with seasonal allergic rhinitis

1 reference

12 December 2020

Loratadine blockade of K(+) channels in human heart: comparison with terfenadine under physiological conditions

1 reference

12 December 2020

Comparison of the efficacy, safety, and onset of action of mizolastine, cetirizine, and placebo in the management of seasonal allergic rhinoconjunctivitis. MIZOCET Study Group

1 reference

12 December 2020

The nature of the vaso-dilator constituents of certain tissue extracts

1 reference

12 December 2020

Comparison of the response to histamine challenge of the nose and the maxillary sinus: effect of loratadine

1 reference

12 December 2020

QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience

1 reference

12 December 2020

In vivo effects of cetirizine on cutaneous reactivity and eosinophil migration induced by platelet-activating factor (PAF-acether) in man.

1 reference

12 December 2020

Effects of antihistamines on inflammatory mediators

1 reference

12 December 2020

Urticarial intolerance reaction to cetirizine

1 reference

12 December 2020

Severe hepatitis in a patient taking cetirizine

1 reference

12 December 2020

The acute and sub-chronic effects of levocetirizine, cetirizine, loratadine, promethazine and placebo on cognitive function, psychomotor performance, and weal and flare

1 reference

12 December 2020

Cetirizine Pharmacokinetics and Pharmacodynamics in Primary Biliary Cirrhosis

1 reference

12 December 2020

Lack of potentiation by cetirizine of alcohol-induced psychomotor disturbances

1 reference

12 December 2020

Long-term cetirizine treatment reduces allergic symptoms and drug prescriptions in children with mite allergy

1 reference

12 December 2020

H1-antihistaminic activity of cetirizine and fexofenadine in allergic children

1 reference

12 December 2020

Effect of loratadine on immediate and delayed type hypersensitivity reactions

1 reference

12 December 2020

Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposure.

1 reference

12 December 2020

Cetirizine treatment of rhinitis in children with pollen allergy: evidence of its antiallergic activity

1 reference

12 December 2020

Fexofenadine's effects, alone and with alcohol, on actual driving and psychomotor performance

1 reference

12 December 2020

Efficacy and safety relative to placebo of an oral formulation of cetirizine and sustained-release pseudoephedrine in the management of nasal congestion

1 reference

12 December 2020

Antitussive action of antihistamines is independent of sedative and ventilation activity in the guinea pig.

1 reference

12 December 2020

CNS effects in the correct perspective

1 reference

12 December 2020

Assessment of the wheal size and skin blood flow of the erythema induced by histamine and its modification with cetirizine and ebastine: a crossover, double-blind study

1 reference

12 December 2020

Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics

1 reference

12 December 2020

Grapefruit juice activates P-glycoprotein-mediated drug transport

1 reference

12 December 2020

Decongestant efficacy of desloratadine in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Prolonged QTc time and ventricular arrhythmia with fexofenadine

1 reference

12 December 2020

Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein

1 reference

12 December 2020

Chronic urticaria: pathogenesis and treatment

1 reference

12 December 2020

Comparative effects of loratadine and terfenadine on cardiac K+ channels

1 reference

12 December 2020

Twenty-four hours of activity of cetirizine and fexofenadine in the skin

1 reference

12 December 2020

Optimizing quality of care and cost effectiveness in treating allergic rhinitis in a managed care setting.

1 reference

12 December 2020

Fexofenadine in chronic idiopathic urticaria: a clinical and immunohistochemical evaluation

1 reference

12 December 2020

Specific review of the psychometric effects of cetirizine

1 reference

12 December 2020

Cardiovascular safety of fexofenadine HCl.

1 reference

12 December 2020

Cetirizine therapy for seasonal allergic rhinitis: alternative dosage schedules

1 reference

12 December 2020

Acute hepatitis associated with cetirizine intake

1 reference

12 December 2020

Assessment of antihistamine efficacy and potency

1 reference

12 December 2020

Effect of descarboethoxyloratadine, the major metabolite of loratadine, on the human cardiac potassium channel Kv1.5.

1 reference

12 December 2020

Cetirizine in patients with seasonal rhinitis and concomitant asthma: prospective, randomized, placebo-controlled trial

1 reference

12 December 2020

Variations among non-sedating antihistamines: are there real differences?

1 reference

12 December 2020

Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow

1 reference

12 December 2020

The effect of cetirizine on symptoms and signs of nasal polyposis

1 reference

12 December 2020

The clinical efficacy of antihistamines in the upper and lower airway

1 reference

12 December 2020

The systemic safety of fexofenadine HCl.

1 reference

12 December 2020

A comparison of Cetirizine, Ebastine, Epinastine, Fexofenadine, Terfenadine, and Loratadine versus placebo in suppressing the cutaneous response to histamine

1 reference

12 December 2020

Improvement of quality of life by treatment with cetirizine in patients with perennial allergic rhinitis as determined by a French version of the SF-36 questionnaire.

1 reference

12 December 2020

Evaluation of cetirizine in patients with allergic rhinitis and perennial asthma

1 reference

12 December 2020

FDA panel recommends OTC status for second-generation antihistamines

1 reference

12 December 2020

Sedative effects of antihistamines

1 reference

12 December 2020

Urticaria induced by cetirizine

1 reference

12 December 2020

Onset of action, efficacy, and safety of a single dose of fexofenadine hydrochloride for ragweed allergy using an environmental exposure unit

1 reference

12 December 2020

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

12 December 2020

Pharmacokinetics of loratadine and its active metabolite descarboethoxyloratadine in healthy Chinese subjects

1 reference

12 December 2020

Cellular inflammatory responses during immediate, developing, and established late-phase allergic cutaneous reactions: effects of cetirizine

1 reference

12 December 2020

Modulation of potassium channels by antiarrhythmic and antihypertensive drugs

1 reference

12 December 2020

Pharmacological Modulation by Cetirizine and Ebastine of the Cutaneous Reactivity to Histamine

1 reference

12 December 2020

Multiple fixed drug eruptions due to cetirizine

1 reference

12 December 2020

Comparison of the effects of terfenadine with fexofenadine on nasal provocation tests with allergen

1 reference

12 December 2020

The role of basophils and mast cells in acute and late reactions in the skin

1 reference

12 December 2020

The effects of fexofenadine on reaction time, decision-making, and driver behavior

1 reference

12 December 2020

Effect of cetirizine on mast cell-mediator release and cellular traffic during the cutaneous late-phase reaction

1 reference

12 December 2020

Acute Effects of Substance P and Calcitonin Gene-Related Peptide in Human Skin – A Microdialysis Study

1 reference

12 December 2020

Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

A double-blinded, randomized, placebo-controlled trial of cetirizine in preventing the onset of asthma in children with atopic dermatitis: 18 months' treatment and 18 months' posttreatment follow-up

1 reference

12 December 2020

Intranasal fluticasone propionate versus loratadine in the treatment of adolescent patients with seasonal allergic rhinitis

1 reference

12 December 2020

Effectiveness and safety of fexofenadine, a new nonsedating H1-receptor antagonist, in the treatment of fall allergies

1 reference

12 December 2020

Simulated assembly line performance following ingestion of cetirizine or hydroxyzine

1 reference

12 December 2020

Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion

1 reference

12 December 2020

The physiological action of beta-iminazolylethylamine

1 reference

12 December 2020

Changes in skin-test reactivity do not correlate with clinical efficacy of H1-blockers in seasonal allergic rhinitis

1 reference

12 December 2020

Histamine and the nasal vasculature: the influence of H1 and H2-histamine receptor antagonism

1 reference

12 December 2020

Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours

1 reference

12 December 2020

Safety and efficacy of once-daily fexofenadine HCl in the treatment of autumn seasonal allergic rhinitis.

1 reference

12 December 2020

Effect of cetirizine on antigen-induced tracheal contraction of passively sensitized guinea pigs

1 reference

12 December 2020

Suppression of histamine-induced wheal response by loratadine (SCH 29851) over 28 days in man.

1 reference

12 December 2020

Sedation and performance impairment of diphenhydramine and second-generation antihistamines: A meta-analysis

1 reference

12 December 2020

Cardiotoxicity of histamine and the possible role of histamine in the arrhythmogenesis produced by certain antihistamines.

1 reference

12 December 2020

In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines

1 reference

12 December 2020

Effect of H1 and H2 antagonists on nasal symptoms and mediator release in atopic patients after nasal allergen challenge during the pollen season

1 reference

12 December 2020

Allergic rhinitis and its impact on asthma

1 reference

12 December 2020

Consistency of the efficacy of cetirizine and ebastine on skin reactivity

1 reference

12 December 2020

Effects of fexofenadine, diphenhydramine, and placebo on performance of the test of variables of attention (TOVA).

1 reference

12 December 2020

Loratadine: multiple-dose pharmacokinetics.

1 reference

12 December 2020

Rhinitis therapy and the prevention of hospital care for asthma: a case-control study

1 reference

12 December 2020

Absorption and disposition of levocetirizine, the eutomer of cetirizine, administered alone or as cetirizine to healthy volunteers

1 reference

12 December 2020

Sedation in allergic rhinitis is caused by the condition and not by antihistamine treatment

1 reference

12 December 2020

Comparative analysis of the cardiotoxicity proclivities of second generation antihistamines in an experimental model predictive of adverse clinical ECG effects.

1 reference

12 December 2020

Once-daily cetirizine effective in the treatment of seasonal allergic rhinitis in children aged 6 to 11 years: a randomized, double-blind, placebo-controlled study

1 reference

12 December 2020

Effects of Cetirizine on Human Eosinophil and Neutrophil Activation in vitro

1 reference

12 December 2020

Controlled comparison of the efficacy and safety of cetirizine 10 mg o.d. and fexofenadine 120 mg o.d. in reducing symptoms of seasonal allergic rhinitis

1 reference

12 December 2020

Loratadine and ventricular tachycardia

1 reference

12 December 2020

Effect of cetirizine, ketotifen and chlorpheniramine on the dynamics of the cutaneous hypersensitivity reaction: a comparative study

1 reference

12 December 2020

Behavioral effects of histamine H1 antagonists: comparison with other drugs and modification by haloperidol.

1 reference

12 December 2020

Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria

1 reference

12 December 2020

Central nervous system effects of H1-receptor antagonists in the elderly

1 reference

12 December 2020

Platelet-Activating Factor-Induced Immediate and Late Cutaneous Reactions

1 reference

12 December 2020

The pharmacology and use of H1-receptor-antagonist drugs

1 reference

12 December 2020

Lack of Clinically Relevant Interaction of Cetirizine on Theophylline Disposition in Healthy Subjects: A Placebo-Controlled Study

1 reference

12 December 2020

A randomized, double-blind, crossover comparison among cetirizine, levocetirizine, and ucb 28557 on histamine-induced cutaneous responses in healthy adult volunteers

1 reference

12 December 2020

Quantitation of H1-receptor antagonists in skin and serum

1 reference

12 December 2020

Channel specificity in antiarrhythmic drug action. Mechanism of potassium channel block and its role in suppressing and aggravating cardiac arrhythmias

1 reference

12 December 2020

Antihistamines and production of granulocyte-macrophage colony-stimulating factor and interleukin-8 by human bronchial epithelial cells in vitro: evaluation of the effects of loratadine and cetirizine

1 reference

12 December 2020

Cetirizine-induce cholestasis

1 reference

12 December 2020

The economic impact of payer policies after the Rx-to-OTC switch of second-generation antihistamines

1 reference

12 December 2020

Efficacy of ebastine, cetirizine, and loratadine in histamine cutaneous challenges

1 reference

12 December 2020

Central effects of fexofenadine and cetirizine: measurement of psychomotor performance, subjective sleepiness, and brain histamine H1-receptor occupancy using 11C-doxepin positron emission tomography

1 reference

12 December 2020

Risks of non-sedating antihistamines

1 reference

12 December 2020

Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine

1 reference

12 December 2020

Molecular biology of the long QT syndrome: impact on management.

1 reference

12 December 2020

Pharmacokinetics of loratadine in patients with renal insufficiency

1 reference

12 December 2020

Allergic rhinitis: not purely a histamine-related disease

1 reference

12 December 2020

Double-blind crossover study of high-dose cetirizine in cholinergic urticaria.

1 reference

12 December 2020

Comparative clinical efficacy, onset and duration of action of levocetirizine and desloratadine for symptoms of seasonal allergic rhinitis in subjects evaluated in the Environmental Exposure Unit (EEU).

1 reference

12 December 2020

Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis

1 reference

12 December 2020

Inhibition of cytokine secretion from human leukemic mast cells and basophils by H1- and H2-receptor antagonists

1 reference

12 December 2020

Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator

1 reference

12 December 2020

Intranasal Azelastine

1 reference

12 December 2020

Maculopapular and urticarial eruption from cetirizine

1 reference

12 December 2020

Sedation and performance issues in the treatment of allergic conditions

1 reference

12 December 2020

Efficacy of cetirizine in cholinergic urticaria

1 reference

12 December 2020

Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis

1 reference

12 December 2020

Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis

1 reference

12 December 2020

Inhibition of cold urticaria by desloratadine

1 reference

12 December 2020

QT lengthening and life-threatening arrhythmias associated with fexofenadine

1 reference

12 December 2020

Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine

1 reference

12 December 2020

The metabolic profile of second-generation antihistamines

1 reference

12 December 2020

Cetirizine and levocetirizine inhibit eotaxin-induced eosinophil transendothelial migration through human dermal or lung microvascular endothelial cells

1 reference

12 December 2020

The effect of antihistamines on the immediate allergic response: a comparative review

1 reference

12 December 2020

Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells.

1 reference

12 December 2020

Psychometric aspects of antihistamines

1 reference

12 December 2020

QT lengthening and life-threatening arrhythmias associated with fexofenadine

1 reference

12 December 2020

Differential effects of new-generation H1-receptor antagonists in pruritic dermatoses.

1 reference

12 December 2020

Role of antigen-induced cytokine release in atopic pruritus

1 reference

12 December 2020

Inhibition of interleukin-4 and interleukin-13 release from immunologically activated human basophils due to the actions of anti-allergic drugs

1 reference

12 December 2020

The role of drug transporters at the blood-brain barrier

1 reference

12 December 2020

The clinical relevance of the anti-inflammatory properties of antihistamines

1 reference

12 December 2020

A comparison of the pharmacodynamics of H1‐receptor antagonists as assessed by the induced wheal‐and‐flare model

1 reference

12 December 2020

Onset of action and efficacy of terfenadine, astemizole, cetirizine, and loratadine for the relief of symptoms of allergic rhinitis.

1 reference

12 December 2020

Effects of emedastine and cetirizine, alone and with alcohol, on actual driving of males and females

1 reference

12 December 2020

The influence of antihistamines on human performance

1 reference

12 December 2020

Improvements in simulated real-world relevant performance for patients with seasonal allergic rhinitis: impact of desloratadine

1 reference

12 December 2020

P-glycoprotein influences the brain concentrations of cetirizine (Zyrtec), a second-generation non-sedating antihistamine.

1 reference

12 December 2020

The effects of single-dose fexofenadine, diphenhydramine, and placebo on cognitive performance in flight personnel

1 reference

12 December 2020

Effect of haemodialysis on the pharmacokinetics of cetirizine

1 reference

12 December 2020

Cetirizine and hydrocortisone differentially regulate ICAM-1 expression and chemokine release in cultured human keratinocytes

1 reference

12 December 2020

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine

1 reference

12 December 2020

Therapeutic options in allergic disease: antihistamines as systemic antiallergic agents

1 reference

12 December 2020

Cardiac ion channels and antihistamines: possible mechanisms of cardiotoxicity

1 reference

12 December 2020

Cetirizine, loratadine, or placebo in subjects with seasonal allergic rhinitis: effects after controlled ragweed pollen challenge in an environmental exposure unit

1 reference

12 December 2020

Assessment of the efficacy and safety of three dose levels of cetirizine given once daily in children with perennial allergic rhinitis

1 reference

12 December 2020

Model for outcomes assessment of antihistamine use for seasonal allergic rhinitis.

1 reference

12 December 2020

Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis.

1 reference

12 December 2020

Inhibition of human eosinophil chemotaxis and of the IgE-dependent stimulation of human blood platelets by cetirizine

1 reference

12 December 2020

Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis.

1 reference

12 December 2020

Detection of proarrhythmia in the female rabbit heart: blinded validation

1 reference

12 December 2020

Efficacy and safety of desloratadine in the treatment of perennial allergic rhinitis

1 reference

12 December 2020

Cetirizine reduces ICAM-I on epithelial cells during nasal minimal persistent inflammation in asymptomatic children with mite-allergic asthma

1 reference

12 December 2020

Spontaneous reporting of suspected adverse reactions to antihistamines: a national and international perspective.

1 reference

12 December 2020

Consistency and efficacy of cetirizine (10 mg) versus ebastine (20 mg) at 4 h on skin reactivity

1 reference

12 December 2020

Effects of loratadine on anti-IgE-induced inflammation, histamine release, and leukocyte recruitment in skin of atopics

1 reference

12 December 2020

Clinical pharmacology of the H1-receptor antagonists cetirizine and loratadine in children

1 reference

12 December 2020

Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.

1 reference

12 December 2020

Pharmacokinetics of loratadine and pseudoephedrine following single and multiple doses of once- versus twice-daily combination tablet formulations in healthy adult males.

1 reference

12 December 2020

Use of cetirizine in dermatologic disorders

1 reference

12 December 2020

Pharmacokinetic overview of oral second-generation H1 antihistamines.

1 reference

12 December 2020

A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function

1 reference

12 December 2020

Transfer of drugs and other chemicals into human milk

1 reference

12 December 2020

Comparative outdoor study of the efficacy, onset and duration of action, and safety of cetirizine, loratadine, and placebo for seasonal allergic rhinitis

1 reference

12 December 2020

Receptors mediating some actions of histamine

1 reference

12 December 2020

Randomized double-blind study of cyclosporin in chronic 'idiopathic' urticaria.

1 reference

12 December 2020

Transitioning the second-generation antihistamines to over-the-counter status: a cost-effectiveness analysis

1 reference

12 December 2020

Cardiotoxicity of new antihistamines and cisapride

1 reference

12 December 2020

Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action

1 reference

12 December 2020

Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole

1 reference

12 December 2020

A pharmacokinetic evaluation of the second-generation H1-receptor antagonist cetirizine in very young children

1 reference

12 December 2020

Glottis oedema due to loratadine

1 reference

12 December 2020

Management of rhinitis and asthma in pregnancy

1 reference

12 December 2020

Nonsedating antihistamines should be preferred over sedating antihistamines in patients who drive.

1 reference

12 December 2020

Desloratadine activity in concurrent seasonal allergic rhinitis and asthma

1 reference

12 December 2020

Advances in H1-antihistamines

1 reference

12 December 2020

Once-daily fexofenadine HCl improves quality of life and reduces work and activity impairment in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Design, synthesis and antihistaminic (H1)activity of some condensed 2-(substituted)arylaminoethylpyrimidin-4(3H)-ones

1 reference

12 December 2020

H1-antihistamines in children

1 reference

12 December 2020

Inhibitory effect of cetirizine on cytokine-enhanced in vitro eosinophil survival

1 reference

12 December 2020

The role of ketoconazole in the QTc interval prolonging effects of H1-antihistamines in a guinea-pig model of arrhythmogenicity

1 reference

12 December 2020

Treating allergic rhinitis in pregnancy. Safety considerations

1 reference

12 December 2020

Cetirizine: a new therapeutic alternative for chronic urticaria.

1 reference

12 December 2020

Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding

1 reference

12 December 2020

Treating allergic rhinitis in patients with comorbid asthma: the risk of asthma-related hospitalizations and emergency department visits

1 reference

12 December 2020

A pharmacokinetic profile of desloratadine in healthy adults, including elderly

1 reference

12 December 2020

Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor

1 reference

12 December 2020

Comparative tolerability of second generation antihistamines

1 reference

12 December 2020

Predictors of torsades de pointes in rabbit ventricles perfused with sedating and nonsedating histamine H1-receptor antagonists

1 reference

12 December 2020

A comprehensive account on the role of efflux transporters in the gastrointestinal absorption of 13 commonly used substrate drugs in humans.

1 reference

12 December 2020

Studies on performance and sleepiness with the H1-antihistamine, desloratadine

1 reference

12 December 2020

Twenty-four-hour activity and consistency of activity of levocetirizine and desloratadine in the skin

1 reference

12 December 2020

Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine

1 reference

12 December 2020

The metabolism and pharmacokinetics of 14C-cetirizine in humans

1 reference

12 December 2020

Ocular drying associated with oral antihistamines (loratadine) in the normal population-an evaluation of exaggerated dose effect.

1 reference

12 December 2020

The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

1 reference

12 December 2020

Anti-inflammatory actions of new antihistamines

1 reference

12 December 2020

Fexofenadine hydrochloride, 180 mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis

1 reference

12 December 2020

Efficacy and safety of cetirizine therapy in perennial allergic rhinitis

1 reference

12 December 2020

Quality of life in allergic rhinitis

1 reference

12 December 2020

The pharmacokinetics, electrocardiographic effects, and tolerability of loratadine syrup in children aged 2 to 5 years

1 reference

12 December 2020

Pharmacologic evaluation of loratadine (SCH 29851), chlorpheniramine and placebo

1 reference

12 December 2020

Suppressive activity of fexofenadine hydrochloride on thymus- and activation-regulated chemokine production from human peripheral blood leukocytes in response to antigenic stimulation in vitro

1 reference

12 December 2020

Continuous versus on demand treatment with cetirizine for allergic rhinitis

1 reference

12 December 2020

Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: a dermal microdialysis study.

1 reference

12 December 2020

Evaluation of the cardiac safety of second-generation antihistamines

1 reference

12 December 2020

Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis

1 reference

12 December 2020

Interactions of the nonsedating antihistamine loratadine with a Kv1.5-type potassium channel cloned from human heart

1 reference

12 December 2020

Prospects for antihistamines in the treatment of asthma

1 reference

12 December 2020

Peripheral H1-blockade effect of fexofenadine

1 reference

12 December 2020

Cetirizine overdose in a young child

1 reference

12 December 2020

In vitro effects of cetirizine and histamine on human neutrophil function

1 reference

12 December 2020

Pregnancy outcome after gestational exposure to loratadine or antihistamines: a prospective controlled cohort study

1 reference

12 December 2020

Effect of 60 mg twice-daily fexofenadine HCl on quality of life, work and classroom productivity, and regular activity in patients with chronic idiopathic urticaria

1 reference

12 December 2020

The effect of cetirizine on sulfidoleukotriene production by blood leukocytes in children with allergic rhinitis

1 reference

12 December 2020

Measurement of interstitial cetirizine concentrations in human skin: correlation of drug levels with inhibition of histamine-induced skin responses

1 reference

12 December 2020

Increased risk of serious injury following an initial prescription for diphenhydramine

1 reference

12 December 2020

The contribution of histamine to the action of bradykinin in the human nasal airway

1 reference

12 December 2020

Sedation with "non-sedating" antihistamines: four prescription-event monitoring studies in general practice

1 reference

12 December 2020

Urticaria to cetirizine.

1 reference

12 December 2020

Histamine H1 receptor antagonism by cetirizine in isolated guinea pig tissues: influence of receptor reserve and dissociation kinetics

1 reference

12 December 2020

Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration

1 reference

12 December 2020

Anti-inflammatory agents and allergen-induced beta2-receptor dysfunction in isolated human bronchi

1 reference

12 December 2020

Safety and efficacy of loratadine in urticaria

1 reference

12 December 2020

Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models

1 reference

12 December 2020

Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis

1 reference

12 December 2020

Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall

1 reference

12 December 2020

Effect of cetirizine, levocetirizine, and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers

1 reference

12 December 2020

Fexofenadine HCl is safe and effective for treatment of chronic idiopathic urticaria

1 reference

12 December 2020

Eosinophilic cellulitis in a child successfully treated with cetirizine

1 reference

12 December 2020

Effect of St John's wort on the pharmacokinetics of fexofenadine

1 reference

12 December 2020

H1 antagonists: receptor affinity versus selectivity

1 reference

12 December 2020

Nonclassical clinical indications for H1‐receptor antagonists in dermatology

1 reference

12 December 2020

Desloratadine in the treatment of chronic idiopathic urticaria

1 reference

12 December 2020

Binding characteristics of cetirizine and levocetirizine to human H(1) histamine receptors: contribution of Lys(191) and Thr(194).

1 reference

12 December 2020

Evaluation of the pharmacokinetics and electrocardiographic pharmacodynamics of loratadine with concomitant administration of ketoconazole or cimetidine

1 reference

12 December 2020

Long QT syndromes and torsade de pointes

1 reference

12 December 2020

Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness

1 reference

12 December 2020

Determining the structure and mechanism of the human multidrug resistance P-glycoprotein using cysteine-scanning mutagenesis and thiol-modification techniques

1 reference

12 December 2020

Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria

1 reference

12 December 2020

Antiasthmatic effects of mediator blockade versus topical corticosteroids in allergic rhinitis and asthma

1 reference

12 December 2020

Torsades de Pointes and QT Prolongation Due to a Combination of Loratadine and Amiodarone

1 reference

12 December 2020

Terfenadine pharmacokinetics in breast milk in lactating women

1 reference

12 December 2020

Histamine-induced skin reactions using iontophoresis and H1-blockade

1 reference

12 December 2020

Preclinical comparison of ebastine and other second generation H1-antihistamines

1 reference

12 December 2020

Comparative pharmacology of H1 antihistamines: clinical relevance

1 reference

12 December 2020

Factors involved in the absence of sedative effects by the second-generation antihistamines

1 reference

12 December 2020

Effects of grapefruit juice and orange juice on the intestinal efflux of P-glycoprotein substrates.

1 reference

12 December 2020

Desloratadine reduces nasal congestion in patients with intermittent allergic rhinitis

1 reference

12 December 2020

Inhibition of eosinophil chemotaxis by a new antiallergic compound (cetirizine).

1 reference

12 December 2020

Efficacy and safety of loratadine plus pseudoephedrine in patients with seasonal allergic rhinitis and mild asthma

1 reference

12 December 2020

Characterization of antihistamines using biphasic cutaneous reaction in BALB/c mice.

1 reference

12 December 2020

1 reference

12 December 2020

Development and validation of the mini Rhinoconjunctivitis Quality of Life Questionnaire.

1 reference

12 December 2020

Cutaneous drug eruption from cetirizine and hydroxyzine

1 reference

12 December 2020

Dose-ranging comparative evaluation of cetirizine in patients with seasonal allergic rhinitis

1 reference

12 December 2020

Intranasal corticosteroids for allergic rhinitis: superior relief?

1 reference

12 December 2020

A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.

1 reference

12 December 2020

Introduction to antihistamine agents and antergan derivative

1 reference

12 December 2020

Double-blind, placebo-controlled study comparing the efficacy and safety of fexofenadine hydrochloride (120 and 180 mg once daily) and cetirizine in seasonal allergic rhinitis

1 reference

12 December 2020

Clinical prescribing of allergic rhinitis medication in the preschool and young school-age child: what are the options?

1 reference

12 December 2020

The use of anti‐H1drugs in mild asthma

1 reference

12 December 2020

Comprehensive evaluation of cetirizine in the management of seasonal allergic rhinitis: impact on symptoms, quality of life, productivity, and activity impairment.

1 reference

12 December 2020

Drug interactions with grapefruit juice: an update

1 reference

12 December 2020

Oral bioavailability of desloratadine is unaffected by food

1 reference

12 December 2020

Block of human cardiac Kv1.5 channels by loratadine: voltage-, time- and use-dependent block at concentrations above therapeutic levels

1 reference

12 December 2020

Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs

1 reference

12 December 2020

Loratadine. A reappraisal of its pharmacological properties and therapeutic use in allergic disorders

1 reference

12 December 2020

Comparison of montelukast and fexofenadine for chronic idiopathic urticaria.

1 reference

12 December 2020

Esophageal retention of loratadine plus pseudoephedrine extended-release tablets (Claritin-D 24 Hour)

1 reference

12 December 2020

Suppression of the early and late cutaneous allergic responses using fexofenadine and montelukast

1 reference

12 December 2020

Assessing predictors of drug-induced torsade de pointes.

1 reference

12 December 2020

1 reference

12 December 2020

Lack of interaction between two antihistamines, mizolastine and cetirizine, and ethanol in psychomotor and driving performance in healthy subjects

1 reference

12 December 2020

A comparison of the clinical efficacy and safety of intranasal fluticasone propionate and antihistamines in the treatment of rhinitis

1 reference

12 December 2020

Cost-benefit analysis of first-generation antihistamines in the treatment of allergic rhinitis

1 reference

12 December 2020

Antihistamines and aircrew: usefulness of fexofenadine.

1 reference

12 December 2020

Cetirizine-induced urticarial reaction

1 reference

12 December 2020

First do no harm: managing antihistamine impairment in patients with allergic rhinitis.

1 reference

12 December 2020

Failure of cetirizine and fexofenadine to prevent motion sickness

1 reference

12 December 2020

Pharmacologic modulation by cetirizine of some adhesion molecules expression in psoriatic skin lesions

1 reference

12 December 2020

Functional characterization of monocarboxylic acid, large neutral amino acid, bile acid and peptide transporters, and P-glycoprotein in MDCK and Caco-2 cells

1 reference

12 December 2020

The metabolism of antihistamines and drug interactions: the role of cytochrome P450 enzymes

1 reference

12 December 2020

Desloratadine shows no effect on performance during 6 h at 8,000 ft simulated cabin altitude.

1 reference

12 December 2020

Effect of desloratadine versus placebo on nasal airflow and subjective measures of nasal obstruction in subjects with grass pollen-induced allergic rhinitis in an allergen-exposure unit

1 reference

12 December 2020

Superiority of an intranasal corticosteroid compared with an oral antihistamine in the as-needed treatment of seasonal allergic rhinitis

1 reference

12 December 2020

Long-term treatment with cetirizine of infants with atopic dermatitis: a multi-country, double-blind, randomized, placebo-controlled trial (the ETAC trial) over 18 months

1 reference

12 December 2020

Effect of H1 receptor blockade on the early and late response to cutaneous allergen challenge

1 reference

12 December 2020

H1-receptor antagonists. Comparative tolerability and safety

1 reference

12 December 2020

Potential cardiac toxicity of H1-antihistamines.

1 reference

12 December 2020

Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human

1 reference

12 December 2020

Fexofenadine: a review of its use in the management of seasonal allergic rhinitis and chronic idiopathic urticaria

1 reference

12 December 2020

Oculogyric crisis in patients taking cetirizine

1 reference

12 December 2020

Cetirizine and loratadine: a comparison using the ED50 in skin reactions

1 reference

12 December 2020

Cetirizine versus hydroxyzine and placebo in chronic idiopathic urticaria

1 reference

12 December 2020

Excretion of loratadine in human breast milk

1 reference

12 December 2020

Chronic urticaria: pathophysiology and treatment approaches.

1 reference

12 December 2020

Antihistamines, drowsiness, and psychomotor impairment: central nervous system effect of cetirizine.

1 reference

12 December 2020

Cellular inflammatory responses and mediator release during early developing late-phase allergic cutaneous inflammatory responses: Effects of cetirizine

1 reference

12 December 2020

The evolution of pharmacotherapy for rhinitis and urticaria.

1 reference

12 December 2020

G proteins as biological targets for anti-allergic drugs?

1 reference

12 December 2020

The electrocardiographic effects of cetirizine in normal subjects

1 reference

12 December 2020

Retrospective evaluation of cetirizine (zyrtec) ingestion.

1 reference

12 December 2020

Effects of antihistamines on leukotriene and cytokine release from dispersed nasal polyp cells

1 reference

12 December 2020

24-hour efficacy of once-daily desloratadine therapy in patients with seasonal allergic rhinitis [ISRCTN32042139]

1 reference

12 December 2020

Ventricular tachycardia following ingestion of a commonly used antihistamine

1 reference

12 December 2020

Second-generation antihistamines: a comparative review

1 reference

12 December 2020

Loratadine treatment of rhinitis due to pollen allergy reduces epithelial ICAM-1 expression

1 reference

12 December 2020

Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised controlled trials

1 reference

12 December 2020

Safety of antihistamines in children

1 reference

12 December 2020

Central effects of the H1-antihistamine, cetirizine

1 reference

12 December 2020

Variant effect of first- and second-generation antihistamines as clues to their mechanism of action on the sneeze reflex in the common cold

1 reference

12 December 2020

Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow

1 reference

12 December 2020

Single-dose pharmacokinetics of cetirizine in patients with chronic liver disease

1 reference

12 December 2020

Effect of cetirizine, a potent H1 antagonist, on platelet activating factor induced bronchoconstriction in asthma

1 reference

12 December 2020

Treatment strategies designed to minimize medical complications of allergic rhinitis.

1 reference

12 December 2020

Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein

1 reference

12 December 2020

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

1 reference

12 December 2020

Treatment of allergic rhinitis

1 reference

12 December 2020

Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis

1 reference

12 December 2020

Evaluation of the safety of fexofenadine from experience gained in general practice use in England in 1997.

1 reference

12 December 2020

Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis

1 reference

12 December 2020

Loratadine administered concomitantly with erythromycin: pharmacokinetic and electrocardiographic evaluations

1 reference

12 December 2020

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects

1 reference

12 December 2020

Inhibition of histamine or allergen-induced wheals by a single dose of acrivastine, fexofenadine or cetirizine.

1 reference

12 December 2020

Cetirizine-induced downregulation of airway fibroblast proliferation and function: a rationale for a different approach to allergy treatment?

1 reference

12 December 2020

Effects of cetirizine on the delayed K+ currents in cardiac cells: comparison with terfenadine

1 reference

12 December 2020

Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects.

1 reference

12 December 2020

Chronic urticaria: a role for newer immunomodulatory drugs?

1 reference

12 December 2020

Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofenadine hydrochloride in healthy male volunteers

1 reference

12 December 2020

Roles of histamine in regulation of arousal and cognition: functional neuroimaging of histamine H1 receptors in human brain

1 reference

12 December 2020

The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique

1 reference

12 December 2020

Minimal persistent inflammation may be controlled by cetirizine.

1 reference

12 December 2020

Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals

1 reference

12 December 2020

Fexofenadine reduces nasal congestion in perennial allergic rhinitis

1 reference

12 December 2020

Long-term evaluation of the impact of the h1-receptor antagonist cetirizine on the behavioral, cognitive, and psychomotor development of very young children with atopic dermatitis

1 reference

12 December 2020

Double-blind trials of azelastine nasal spray monotherapy versus combination therapy with loratadine tablets and beclomethasone nasal spray in patients with seasonal allergic rhinitis. Rhinitis Study Groups

1 reference

12 December 2020

Randomized double-blind comparison of cetirizine and fexofenadine after pollen challenge in the Environmental Exposure Unit: duration of effect in subjects with seasonal allergic rhinitis.

1 reference

12 December 2020

A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis

1 reference

12 December 2020

In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes

1 reference

12 December 2020

Torsade de pointes. Mechanisms and management.

1 reference

12 December 2020

Cutaneous responses to substance P and calcitonin gene-related peptide in chronic urticaria: the effect of cetirizine and dimethindene

1 reference

12 December 2020

Rate-dependent blockade of a potassium current in human atrium by the antihistamine loratadine

1 reference

12 December 2020

Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells

1 reference

12 December 2020

Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM‐1 and HLA‐DR by nasal epithelial cells

1 reference

12 December 2020

A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects

1 reference

12 December 2020

Safety of fexofenadine in children treated for seasonal allergic rhinitis

1 reference

12 December 2020

In vitro studies with fexofenadine, a new nonsedating histamine H1 receptor antagonist, on isolated human basophils

1 reference

12 December 2020

Prevention of acute urticaria in young children with atopic dermatitis

1 reference

12 December 2020

Two cases of gynaecomastia with cetirizine, a second-generation antihistamine

1 reference

12 December 2020

Leukotriene B4 production by blood neutrophils in allergic rhinitis—effects of cetirizine

1 reference

12 December 2020

Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences

1 reference

12 December 2020

Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine

1 reference

12 December 2020

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

1 reference

12 December 2020

Cetirizine inhibits skin reactions but not mediator release in immediate and developing late-phase allergic cutaneous reactions. A double-blind, placebo-controlled study

1 reference

12 December 2020

Onset of action in the nasal antihistaminic effect of cetirizine and loratadine in patients with allergic rhinitis

1 reference

12 December 2020

Individual differences in central nervous system response to antihistamines (H1-receptor antagonists)

1 reference

12 December 2020

Cardiac actions of antihistamines

1 reference

12 December 2020

Pharmacokinetic-pharmacodynamic relationships of H1-antihistamines

1 reference

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Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children.

1 reference

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Lipophilicity behaviour of the Zwitterionic antihistamine cetirizine in phosphatidylcholine liposomes/water systems

1 reference

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Addition of fexofenadine to a topical corticosteroid reduces the pruritus associated with atopic dermatitis in a 1-week randomized, multicentre, double-blind, placebo-controlled, parallel-group study

1 reference

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Treatment of allergic rhinitis during pregnancy

1 reference

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Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist

1 reference

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Prospective, long-term safety evaluation of the H1-receptor antagonist cetirizine in very young children with atopic dermatitis. ETAC Study Group. Early Treatment of the Atopic Child.

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Ultrastructural localization of histamine in human basophils and mast cells; changes associated with anaphylactic degranulation and recovery demonstrated with a diamine oxidase-gold probe

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Pharmacokinetics of cetirizine in the elderly and patients with renal insufficiency

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The use of antihistamines in safety-critical jobs: a meeting report

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The effects of acute doses of fexofenadine, promethazine, and placebo on cognitive and psychomotor function in healthy Japanese volunteers

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Studies into the possible central effects of the H-1 receptor antagonist, fexofenadine

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G-proteins in allergy

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The molecular behaviour of cetirizine

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Effects of seasonal allergic rhinitis on selected cognitive abilities

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A controlled study on the effectiveness of loratadine in combination with flunisolide in the treatment of nonallergic rhinitis with eosinophilia (NARES)

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12 December 2020

The Rx-to-OTC switch of Claritin, Allegra, and Zyrtec: an unprecedented FDA response to petitioners and the protection of public health

1 reference

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Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation

1 reference

12 December 2020

An evaluation of the effects of high-dose fexofenadine on the central nervous system: a double-blind, placebo-controlled study in healthy volunteers

1 reference

12 December 2020

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12 December 2020

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12 December 2020

The comparison of the efficacy and safety of cetirizine, oxatomide, ketotifen, and a placebo for the treatment of childhood perennial allergic rhinitis

1 reference

12 December 2020

Safety of second generation antihistamines

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Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements

1 reference

12 December 2020

Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma

1 reference

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Effect of cetirizine on human eosinophil superoxide generation, eosinophil chemotaxis and eosinophil peroxidase in vitro

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Investigating patient experiences after a formulary change

1 reference

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Loratadine versus cetirizine: assessment of somnolence and motivation during the workday

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Intranasal azelastine. A review of its efficacy in the management of allergic rhinitis

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12 December 2020

10.2165/00003495-200565030-00004

Identifiers

DOI

1 reference

Dimensions Publication ID

11 August 2017

1001630329

0 references

Fatcat ID

release_r2sn2im5onfj5d4cevf4tkfb6y

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/r2sn2im5onfj5d4cevf4tkfb6y

24 November 2022

mapped directly with Wikidata item

1 reference