(Q36049200)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

Antiinflammatory and Antimicrobial Effects of Thiocyanate in a Cystic Fibrosis Mouse Model (English)

1 reference

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24 February 2020

0 references

5

1 reference

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24 February 2020

6

Tessa Mocatta

1 reference

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24 February 2020

11

Anthony J Kettle

1 reference

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24 February 2020

author name string

Joshua D Chandler

1

1 reference

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24 February 2020

Elysia Min

2

1 reference

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24 February 2020

Jie Huang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Cameron S McElroy

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Ashley A Fletcher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Christopher M Evans

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Liping Liang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Manisha Patel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

David P Nichols

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Brian J Day

13

1 reference

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24 February 2020

publication date

1 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Respiratory Cell and Molecular Biology

24 February 2020

published in

1 reference

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24 February 2020

volume

53

1 reference

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24 February 2020

issue

2

1 reference

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24 February 2020

page(s)

193-205

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia.

24 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Pyocyanin-induced mucin production is associated with redox modification of FOXA2.

2 October 2017

1 reference

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Nebulized and oral thiol derivatives for pulmonary disease in cystic fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Selective metabolism of hypothiocyanous acid by mammalian thioredoxin reductase promotes lung innate immunity and antioxidant defense

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Nebulized thiocyanate improves lung infection outcomes in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Myeloperoxidase: a front-line defender against phagocytosed microorganisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Thiocyanate: a potentially useful therapeutic agent with host defense and antioxidant properties

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

CFTR is the primary known apical glutathione transporter involved in cigarette smoke-induced adaptive responses in the lung

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Hypochlorous acid-induced heme degradation from lactoperoxidase as a novel mechanism of free iron release and tissue injury in inflammatory diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Macropinocytosis of extracellular glutathione ameliorates tumor necrosis factor α release in activated macrophages

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Hypertonic saline increases lung epithelial lining fluid glutathione and thiocyanate: two protective CFTR-dependent thiols against oxidative injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Small molecular, macromolecular, and cellular chloramines react with thiocyanate to give the human defense factor hypothiocyanite

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Neutrophil apoptosis: a target for enhancing the resolution of inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator-dependent bicarbonate secretion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

The triterpenoid CDDO limits inflammation in preclinical models of cystic fibrosis lung disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Neutrophil apoptosis and the resolution of infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Dysfunction of Nrf-2 in CF epithelia leads to excess intracellular H2O2 and inflammatory cytokine production

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Thiocyanate concentration in saliva of cystic fibrosis patients

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

The lactoperoxidase system links anion transport to host defense in cystic fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Thiocyanate-dependent induction of endothelial cell adhesion molecule expression by phagocyte peroxidases: a novel HOSCN-specific oxidant mechanism to amplify inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

A novel host defense system of airways is defective in cystic fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Myeloperoxidase: friend and foe

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Lactoperoxidase and human airway host defense

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Inflammatory cytokines in cystic fibrosis lungs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Chloride impermeability in cystic fibrosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Transcellular thiocyanate transport by human airway epithelia

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Thiocyanate and chloride as competing substrates for myeloperoxidase.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Characterization of the oxidation products of the reaction between reduced glutathione and hypochlorous acid

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Accumulation of Hypothiocyanite Ion during Peroxidase-Catalyzed Oxidation of Thiocyanate Ion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4566044

Cystic fibrosis: a disease of vulnerability to airway surface dehydration.

27 July 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Production of glutathione sulfonamide and dehydroglutathione from GSH by myeloperoxidase-derived oxidants and detection using a novel LC-MS/MS method

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Simultaneous determination of reduced glutathione, glutathione disulphide and glutathione sulphonamide in cells and physiological fluids by isotope dilution liquid chromatography-tandem mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Preventive but not late amiloride therapy reduces morbidity and mortality of lung disease in betaENaC-overexpressing mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Is thiocyanate peroxidation at equilibrium in vivo?

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Improvement of alveolar glutathione and lung function but not oxidative state in cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Inhalation treatment with glutathione in patients with cystic fibrosis. A randomized clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Oxidation contributes to low glutathione in the airways of children with cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1165%2FRCMB.2014-0208OC

Redox buffering of hypochlorous acid by thiocyanate in physiologic fluids

21 January 2018

1 reference

12 December 2020

Inflammatory mediators in CF patients

1 reference

12 December 2020

The peroxidase-thiocyanate-hydrogen peroxide antimicrobial system

1 reference

12 December 2020

Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilution

1 reference

12 December 2020

Oxidation of chloride and thiocyanate by isolated leukocytes

1 reference

12 December 2020

The development of lung disease in cystic fibrosis pigs

1 reference

12 December 2020

High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

1 reference

12 December 2020

Oxidation of 2-cys peroxiredoxins in human endothelial cells by hydrogen peroxide, hypochlorous acid, and chloramines

1 reference

12 December 2020

Eosinophil peroxidase nitrates protein tyrosyl residues. Implications for oxidative damage by nitrating intermediates in eosinophilic inflammatory disorders

1 reference

12 December 2020

Identifiers

DOI

10.1165/RCMB.2014-0208OC

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25490247%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference