(Q36059506)

11 August 2017

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title

The target discovery process (English)

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11 August 2017

Ursula Egner

1

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11 August 2017

Jörn Krätzschmar

2

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11 August 2017

Bertolt Kreft

3

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11 August 2017

Hans-Dieter Pohlenz

4

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11 August 2017

Martin Schneider

5

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11 August 2017

publication date

1 March 2005

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11 August 2017

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11 August 2017

volume

6

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11 August 2017

issue

3

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11 August 2017

page(s)

468-479

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

11 August 2017

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Drug discovery: a historical perspective

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

21 January 2018

The Protein Data Bank

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Chemogenomic approaches to drug discovery

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

The conformational plasticity of protein kinases

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Structural biology in drug design: selective protein kinase inhibitors

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Recent kinase and kinase inhibitor X-ray structures: mechanisms of inhibition and selectivity insights

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Crystal structure and NMR studies of the apo SH2 domains of ZAP-70: two bikes rather than a tandem

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

The specificities of protein kinase inhibitors: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Src Family Kinases: Potential Targets for the Treatment of Human Cancer and Leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Non-viral gene delivery systems

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Rapid and highly efficient gene transfer into natural killer cells by nucleofection

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Virus-based gene delivery systems

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

The interferon antiviral response: from viral invasion to evasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Host defense, viruses and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

Killing the messenger: short RNAs that silence gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Bypassing a Kinase Activity with an ATP-Competitive Drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Knockouts model the 100 best-selling drugs--will they model the next 100?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Of mice and models: improved animal models for biomedical research

21 January 2018

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https://api.crossref.org/works/10.1002%2FCBIC.200400158

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Recent improvements to the PROSITE database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

The protein kinase complement of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

Induction of an interferon response by RNAi vectors in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIC.200400158

21 January 2018

Identifiers

DOI

10.1002/CBIC.200400158

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11 August 2017

1 reference