(Q36059884)

English

Vismodegib.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Vismodegib. (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1 reference

ChEBI release 2020-05-28

author name string

Andrzej Dlugosz

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Sid Agrawal

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Peter Kirkpatrick

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

publication date

1 June 2012

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

number of pages

2

1 reference

based on heuristic

inferred from page(s)

Nature Reviews Drug Discovery

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

437-438

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

https://scigraph.springernature.com/pub.10.1038/nrd3753

0 references

Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Efficacy and safety of vismodegib in advanced basal-cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

A crucial requirement for Hedgehog signaling in small cell lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

The Hedgehog's tale: developing strategies for targeting cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Phase I trial of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with refractory, locally advanced or metastatic solid tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Pharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Targeting Hedgehog--a cancer stem cell pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

GDC-0449-a potent inhibitor of the hedgehog pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Basal cell carcinomas: attack of the hedgehog

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Hedgehog signaling in animal development: paradigms and principles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Human homolog of patched, a candidate gene for the basal cell nevus syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Mutations affecting segment number and polarity in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

2 October 2017

Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

11 July 2018

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

11 July 2018

Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally bioavailable systemic Hedgehog signalling pathway inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

23 September 2018

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383648

23 September 2018

Basal-cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNRD3753

21 January 2018

Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNRD3753

21 January 2018

Topical treatment of Basal cell carcinomas in nevoid Basal cell carcinoma syndrome with a smoothened inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNRD3753

21 January 2018

Identifiers

10.1038/NRD3753

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36059884&oldid=1980274061"