(Q36063543)

11 August 2017

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title

The role of caspase cleavage of tau in Alzheimer disease neuropathology (English)

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11 August 2017

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Wayne W Poon

2

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author name string

Carl W Cotman

series ordinal

1

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11 August 2017

Robert A Rissman

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3

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11 August 2017

Mathew Blurton-Jones

series ordinal

4

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11 August 2017

language of work or name

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1 February 2005

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Journal of Neuropathology & Experimental Neurology

11 August 2017

published in

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11 August 2017

volume

64

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11 August 2017

issue

2

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11 August 2017

page(s)

104-112

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Neuronal loss, neurofibrillary tangles and granulovacuolar degeneration in the hippocampus with ageing and dementia. A quantitative study

11 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly

21 January 2018

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Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease

21 January 2018

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The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Proapoptotic effects of tau cleavage product generated by caspase-3.

21 January 2018

1 reference

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Active caspase-6 and caspase-6-cleaved tau in neuropil threads, neuritic plaques, and neurofibrillary tangles of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

The neuronal microtubule-associated protein tau is a substrate for caspase-3 and an effector of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Correlation between caspase activation and neurofibrillary tangle formation in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Caspase activation in the limbic cortex of subjects with early Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Oxidative regulation of fatty acid-induced tau polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

A nucleated assembly mechanism of Alzheimer paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Neuronal cell death in Alzheimer's disease correlates with apoE uptake and intracellular Abeta stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Nonsaturable binding indicates clustering of tau on the microtubule surface in a paired helical filament-like conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJNEN%2F64.2.104

21 January 2018

Identifiers

DOI

10.1093/JNEN/64.2.104

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11 August 2017

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