(Q36075232)

12 August 2017

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title

CD19 function in central and peripheral B-cell development (English)

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12 August 2017

Christopher J Del Nagro

1

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12 August 2017

Dennis C Otero

2

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12 August 2017

Amy N Anzelon

3

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12 August 2017

Sidne A Omori

4

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12 August 2017

Ravi V Kolla

5

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12 August 2017

Robert C Rickert

6

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12 August 2017

1 January 2005

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12 August 2017

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12 August 2017

31

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12 August 2017

2

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12 August 2017

119-131

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https://scigraph.springernature.com/pub.10.1385/ir:31:2:119

12 August 2017

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cites work

Phosphorylation of CD19 Y484 and Y515, and linked activation of phosphatidylinositol 3-kinase, are required for B cell antigen receptor-mediated activation of Bruton's tyrosine kinase

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12 December 2020

Positive selection from newly formed to marginal zone B cells depends on the rate of clonal production, CD19, and btk

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12 December 2020

Co-ligation of the antigen and Fc receptors gives rise to the selective modulation of intracellular signaling in B cells. Regulation of the association of phosphatidylinositol 3-kinase and inositol 5'-phosphatase with the antigen receptor complex

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12 December 2020

CD19 function in early and late B cell development: I. Maintenance of follicular and marginal zone B cells requires CD19-dependent survival signals

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12 December 2020

The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens

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12 December 2020

Cognate B cell signaling via MHC class II: differential regulation of B cell antigen receptor and MHC class II/Ig-alpha beta signaling by CD22.

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12 December 2020

CD38 ligation in human B cell progenitors triggers tyrosine phosphorylation of CD19 and association of CD19 with lyn and phosphatidylinositol 3-kinase

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12 December 2020

Variability of CR2 gene products is due to alternative exon usage and different CR2 alleles.

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12 December 2020

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

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12 December 2020

Qualitative regulation of B cell antigen receptor signaling by CD19: selective requirement for PI3-kinase activation, inositol-1,4,5-trisphosphate production and Ca2+ mobilization

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12 December 2020

CD19 function in early and late B cell development. II. CD19 facilitates the pro-B/pre-B transition

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12 December 2020

Immunoglobulin recombinase gene activity is modulated reciprocally by interleukin 7 and CD19 in B cell progenitors

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12 December 2020

The follicular versus marginal zone B lymphocyte cell fate decision is regulated by Aiolos, Btk, and CD21

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12 December 2020

The physiologic role of CD19 cytoplasmic tyrosines

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12 December 2020

Impaired light chain allelic exclusion and lack of positive selection in immature B cells expressing incompetent receptor deficient of CD19.

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12 December 2020

Antiviral protection and germinal center formation, but impaired B cell memory in the absence of CD19.

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12 December 2020

CD72-mediated B cell activation involves recruitment of CD19 and activation of phosphatidylinositol 3-kinase

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12 December 2020

The PI3K-PDK1 connection: more than just a road to PKB

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12 December 2020

Specific binding of Fyn and phosphatidylinositol 3‐kinase to the B cell surface glycoprotein CD19 through their src homology 2 domains

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12 December 2020

Integrin-mediated long-term B cell retention in the splenic marginal zone.

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12 December 2020

Essential role of PDK1 in regulating cell size and development in mice

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12 December 2020

Functional effect of IL-7-enhanced CD19 expression on human B cell precursors.

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12 December 2020

Experimental analysis by site-directed mutagenesis of somatic mutation effects on affinity and fine specificity in antibodies specific for lysozyme

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12 December 2020

Impaired CD40-signalling in CD19-deficient mice selectively affects Th2-dependent isotype switching

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12 December 2020

The activation and subsequent regulatory roles of Lyn and CD19 after B cell receptor ligation are independent

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12 December 2020

Cutting edge: recruitment of the CD19/CD21 coreceptor to B cell antigen receptor is required for antigen-mediated expression of Bcl-2 by resting and cycling hen egg lysozyme transgenic B cells

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12 December 2020

Polymeric C3dg primes human B lymphocytes for proliferation induced by anti-IgM.

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12 December 2020

Marginal zone, but not follicular B cells, are potent activators of naive CD4 T cells.

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12 December 2020

Signaling through CD19 activates Vav/mitogen-activated protein kinase pathway and induces formation of a CD19/Vav/phosphatidylinositol 3-kinase complex in human B cell precursors

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12 December 2020

Complementary roles for CD19 and Bruton's tyrosine kinase in B lymphocyte signal transduction

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12 December 2020

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

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12 December 2020

CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

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12 December 2020

B-cell antigen receptor competence regulates B-lymphocyte selection and survival

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12 December 2020

B cell development: signal transduction by antigen receptors and their surrogates.

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12 December 2020

Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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12 December 2020

Adapter molecule Grb2-associated binder 1 is specifically expressed in marginal zone B cells and negatively regulates thymus-independent antigen-2 responses

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12 December 2020

Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes

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12 December 2020

Fc gammaRIIB1 inhibition of BCR-mediated phosphoinositide hydrolysis and Ca2+ mobilization is integrated by CD19 dephosphorylation

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12 December 2020

A critical role for complement in maintenance of self-tolerance

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12 December 2020

Defects in early B-cell development: comparing the consequences of abnormalities in pre-BCR signaling in the human and the mouse

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12 December 2020

Regulation of B-cell signal transduction by adaptor proteins

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12 December 2020

Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones.

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12 December 2020

Tyrosine phosphorylation of CD19 in pre-B and mature B cells

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12 December 2020

The role of complement in inflammation and adaptive immunity

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12 December 2020

CD19 can regulate B lymphocyte signal transduction independent of complement activation

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12 December 2020

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

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12 December 2020

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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12 December 2020

Modular PH and C2 domains in membrane attachment and other functions

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12 December 2020

Binding analysis of antibodies produced by precursor and branchpoint intermediates of an anti-influenza hemagglutinin B cell clone. Parallel replacement mutations do not confer increased avidity for hemagglutinin.

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12 December 2020

Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers.

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12 December 2020

B cell receptor-mediated Syk-independent activation of phosphatidylinositol 3-kinase, Ras, and mitogen-activated protein kinase pathways

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12 December 2020

Membrane IgM-induced tyrosine phosphorylation of CD19 requires a CD19 domain that mediates association with components of the B cell antigen receptor complex

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12 December 2020

Lsc is required for marginal zone B cells, regulation of lymphocyte motility and immune responses

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12 December 2020

Fc gammaRIIb inhibits both B cell receptor- and CD19-induced Ca2+ mobilization in Fc gammaR-transfected human B cells

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12 December 2020

Distinct signaling requirements for Dmu selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors

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12 December 2020

The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation

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12 December 2020

A molecular and immunochemical characterization of mouse CR2. Evidence for a single gene model of mouse complement receptors 1 and 2.

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12 December 2020

CD19 expression levels regulate B lymphocyte development: human CD19 restores normal function in mice lacking endogenous CD19

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12 December 2020

Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.

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12 December 2020

Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

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12 December 2020

CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes

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12 December 2020

C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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12 December 2020

Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily

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12 December 2020

CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification

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12 December 2020

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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12 December 2020

The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules

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12 December 2020

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors

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12 December 2020

Cd19-dependent activation of Akt kinase in B-lymphocytes

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12 December 2020

The CR2/CD19 complex on human B cells contains the src-family kinase Lyn

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12 December 2020

The CD19/CD21 complex functions to prolong B cell antigen receptor signaling from lipid rafts

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12 December 2020

Functional heterogeneity of marginal zone B cells revealed by their ability to generate both early antibody-forming cells and germinal centers with hypermutation and memory in response to a T-dependent antigen

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12 December 2020

Essential immunoregulatory role for BCAP in B cell development and function

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12 December 2020

Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex

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12 December 2020

Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines

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12 December 2020

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

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12 December 2020

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

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12 December 2020

CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes

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12 December 2020

The signaling activity of murine CD19 is regulated during cell development

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12 December 2020

A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation

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12 December 2020

Cutting edge commentary: origins of B-1 cells

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12 December 2020

CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase

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12 December 2020

The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13.

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12 December 2020

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice

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12 December 2020

Xid-like phenotypes: a B cell signalosome takes shape

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12 December 2020

Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination.

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12 December 2020

Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

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12 December 2020

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

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12 December 2020

The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19

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12 December 2020

Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex.

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12 December 2020

Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function

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12 December 2020

Activation of the EBV/C3d receptor (CR2, CD21) on human B lymphocyte surface triggers tyrosine phosphorylation of the 95-kDa nucleolin and its interaction with phosphatidylinositol 3 kinase

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12 December 2020

SYK is upstream of phosphoinositide 3-kinase in B cell receptor signaling

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12 December 2020

Self-renewal of B-1 lymphocytes is dependent on CD19.

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12 December 2020

Identifiers

DOI

10.1385/IR:31:2:119

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Dimensions Publication ID

12 August 2017

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