(Q36079407)

12 August 2017

Regulation of RAS oncogenicity by acetylation (English)

1 reference

12 August 2017

10

Dafna Bar-Sagi

1 reference

12 August 2017

11

Marcia C Haigis

1 reference

12 August 2017

12

Kevin M Haigis

1 reference

12 August 2017

Moon Hee Yang

1

1 reference

12 August 2017

Seth Nickerson

2

1 reference

12 August 2017

Eric T Kim

3

1 reference

12 August 2017

Caroline Liot

4

1 reference

12 August 2017

Gaelle Laurent

5

1 reference

12 August 2017

Robert Spang

6

1 reference

12 August 2017

Mark R Philips

7

1 reference

12 August 2017

Yibing Shan

8

1 reference

12 August 2017

David E Shaw

9

1 reference

12 August 2017

language of work or name

English

0 references

publication date

18 June 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

1 reference

12 August 2017

109

1 reference

12 August 2017

27

1 reference

12 August 2017

10843-10848

1 reference

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Regulating the regulator: post-translational modification of RAS

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

RAS oncogenes: weaving a tumorigenic web

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

An orthosteric inhibitor of the Ras-Sos interaction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Improved side-chain torsion potentials for the Amber ff99SB protein force field

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Allosteric modulation of Ras positions Q61 for a direct role in catalysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Characterization of a Ras mutant with identical GDP- and GTP-bound structures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Non-redundancy within the RAS oncogene family: insights into mutational disparities in cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Ras oncogenes: split personalities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Tumour maintenance is mediated by eNOS.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Effects of posttranslational modifications on the structure and dynamics of histone H3 N-terminal Peptide

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Comparison of multiple Amber force fields and development of improved protein backbone parameters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Germline KRAS mutations cause Noonan syndrome

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Dynamic properties of the Ras switch I region and its importance for binding to effectors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Farnesyltransferase and geranylgeranyltransferase I inhibitors in cancer therapy: important mechanistic and bench to bedside issues

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Canonical dynamics: Equilibrium phase-space distributions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

The structural basis of the activation of Ras by Sos

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

p21ras is modified by a farnesyl isoprenoid

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

All ras proteins are polyisoprenylated but only some are palmitoylated

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

The structure of Ras protein: a model for a universal molecular switch

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Biological and biochemical properties of human rasH genes mutated at codon 61.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Conformational transitions in p21ras and in its complexes with the effector protein Raf-RBD and the GTPase activating protein GAP.

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

Differential modification of Ras proteins by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

Development of polyphosphate parameters for use with the AMBER force field.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

A common, avoidable source of error in molecular dynamics integrators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

Elucidating membrane protein function through long-timescale molecular dynamics simulation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390846

Is the Ewald summation still necessary? Pairwise alternatives to the accepted standard for long-range electrostatics

23 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1201487109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1201487109

1 reference

12 August 2017

0 references

1 reference

12 August 2017

PubMed publication ID

22711838

1 reference