(Q36087078)

12 August 2017

title

Identifying Novel Type ZBGs and Nonhydroxamate HDAC Inhibitors Through a SVM Based Virtual Screening Approach (English)

1 reference

12 August 2017

1 reference

support vector machine

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

X H Liu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

H Y Song

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

J X Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

B C Han

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

X N Wei

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

X H Ma

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

W K Cui

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

17 May 2010

1 reference

12 August 2017

published in

Molecular Informatics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

407-420

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 June 2020

support vector machine

1 reference

based on heuristic

inferred from title

cites work

Pharmacophore modeling and virtual screening studies to design some potential histone deacetylase inhibitors as new leads.

1 reference

https://api.crossref.org/works/10.1002%2FMINF.200900014

A support vector machines approach for virtual screening of active compounds of single and multiple mechanisms from large libraries at an improved hit-rate and enrichment factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.200900014

Virtual screening using protein-ligand docking: avoiding artificial enrichment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.200900014

Chemical Similarity Searching

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FMINF.200900014

Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

21 January 2018

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Thioamide hydroxypyrothiones supersede amide hydroxypyrothiones in potency against anthrax lethal factor

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

New predictive models for blood-brain barrier permeability of drug-like molecules

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Trichostatin A attenuates airway inflammation in mouse asthma model

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Evaluation of virtual screening performance of support vector machines trained by sparsely distributed active compounds.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Design, synthesis and AChE inhibitory activity of indanone and aurone derivatives

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Virtual screening of molecular databases using a support vector machine.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Structure-based virtual screening of chemical libraries for drug discovery

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Total synthesis and molecular target of largazole, a histone deacetylase inhibitor

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Comparison of the predicted and observed secondary structure of T4 phage lysozyme

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Histone deacetylase inhibitors in cancer therapy

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Synthesis and evaluation of lysine derived sulfamides as histone deacetylase inhibitors.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Classifying "kinase inhibitor-likeness" by using machine-learning methods.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Rational design of non-hydroxamate histone deacetylase inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

The influence of lead discovery strategies on the properties of drug candidates

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and laplacian-modified naive bayesian classifiers

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Histone Deacetylase Inhibitors: The Abbott Experience

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

A new role for old ligands: discerning chelators for zinc metalloproteinases

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Hit discovery and hit-to-lead approaches

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Structure-activity relationships on phenylalanine-containing inhibitors of histone deacetylase: in vitro enzyme inhibition, induction of differentiation, and inhibition of proliferation in Friend leukemic cells.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Evaluation of machine-learning methods for ligand-based virtual screening

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Chemistry, biology, and QSAR studies of substituted biaryl hydroxamates and mercaptoacetamides as HDAC inhibitors-nanomolar-potency inhibitors of pancreatic cancer cell growth

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Screening for new antidepressant leads of multiple activities by support vector machines

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Non-hydroxamate histone deacetylase inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

3-D QSAR Studies on Histone Deacetylase Inhibitors. A GOLPE/GRID Approach on Different Series of Compounds

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Heterocyclic zinc-binding groups for use in next-generation matrix metalloproteinase inhibitors: potency, toxicity, and reactivity

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Epigenetics and human disease

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Virtual screening of chemical libraries

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Novel Hydroxamate and Anilide Derivatives as Potent Histone Deacetylase Inhibitors: Synthesis and Antiproliferative Evaluation

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

In silico prediction of pregnane X receptor activators by machine learning approaches.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Exploration of a binding mode of indole amide analogues as potent histone deacetylase inhibitors and 3D-QSAR analyses

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Pomiferin, histone deacetylase inhibitor isolated from the fruits of Maclura pomifera

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Homology modeling, force field design, and free energy simulation studies to optimize the activities of histone deacetylase inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

A Tutorial on Support Vector Machines for Pattern Recognition

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Principles of QSAR models validation: internal and external

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Charting biologically relevant chemical space: a structural classification of natural products (SCONP)

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

3D-QSAR of histone deacetylase inhibitors: hydroxamate analogues

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

In vitro and ex vivo evaluation of second-generation histone deacetylase inhibitors for the treatment of spinal muscular atrophy

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Earliest pages of bioinformatics

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Anticancer activities of histone deacetylase inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

New methods for ligand-based virtual screening: use of data fusion and machine learning to enhance the effectiveness of similarity searching

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Sulfamides as novel histone deacetylase inhibitors.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

From natural products to small molecule ketone histone deacetylase inhibitors: development of new class specific agents

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides.

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Quantitative structure-activity relationship study of histone deacetylase inhibitors

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

Drug design by machine learning: support vector machines for pharmaceutical data analysis

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

ERIC recommendations on IGHV gene mutational status analysis in chronic lymphocytic leukemia

8 April 2023

1 reference

https://opencitations.net/index/coci/api/v1/references/10.1002/MINF.200900014

8 April 2023

Identifiers

DOI

10.1002/MINF.200900014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27463196%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference