(Q37317209)

English

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?

scientific article published on 17 October 2008

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

28 September 2019

Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on? (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

1 reference

28 September 2019

1 reference

PubMed publication ID

rheumatoid arthritis

1 reference

28 September 2019

histone deacetylases

1 reference

28 September 2019

Aleksander M. Grabiec

object named as

Aleksander M Grabiec

1

0 references

2

object named as

Paul P Tak

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

author name string

Kris A Reedquist

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

17 October 2008

5 references

Europe PubMed Central

PMC publication ID

19 August 2017

13 March 2019

17 June 2019

30 June 2019

28 September 2019

Arthritis Research and Therapy

5 references

Europe PubMed Central

PMC publication ID

19 August 2017

13 March 2019

17 June 2019

30 June 2019

28 September 2019

10

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

226

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

https://scigraph.springernature.com/pub.10.1186/ar2489

0 references

Histone deacetylase inhibitors: new hope for rheumatoid arthritis?

1 reference

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9 September 2017

1 reference

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9 September 2017

Inhibitors of NAD+ dependent histone deacetylases (sirtuins).

1 reference

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9 September 2017

SIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.

1 reference

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9 September 2017

Epigenetic clues to rheumatoid arthritis

1 reference

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9 September 2017

Epigenetics in inflammatory rheumatic diseases

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9 September 2017

Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors

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9 September 2017

Sirtuins: the 'magnificent seven', function, metabolism and longevity

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9 September 2017

Structure and acetyl-lysine recognition of the bromodomain

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9 September 2017

Cytokines in the pathogenesis of rheumatoid arthritis

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9 September 2017

Sirtuins in mammals: insights into their biological function

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9 September 2017

Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.

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9 September 2017

The role of chromatin during transcription

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9 September 2017

Will broad-spectrum histone deacetylase inhibitors be superseded by more specific compounds?

1 reference

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9 September 2017

Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis.

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9 September 2017

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

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9 September 2017

Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10

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9 September 2017

Histone deacetylase inhibitors prevent exocytosis of interleukin-1beta-containing secretory lysosomes: role of microtubules

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9 September 2017

The complexity of p53 stabilization and activation

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9 September 2017

Genomic DNA methylation: the mark and its mediators

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9 September 2017

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

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9 September 2017

Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-kappaB suppression

1 reference

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9 September 2017

Acetylation and deacetylation of non-histone proteins

1 reference

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9 September 2017

Trichostatin A sensitises rheumatoid arthritis synovial fibroblasts for TRAIL-induced apoptosis

1 reference

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9 September 2017

Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation

1 reference

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9 September 2017

Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study

1 reference

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9 September 2017

The molecular basis for the effectiveness, toxicity, and resistance to glucocorticoids: focus on the treatment of rheumatoid arthritis

1 reference

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9 September 2017

Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

9 September 2017

Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer

1 reference

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9 September 2017

Understanding the genetic contribution to rheumatoid arthritis

1 reference

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9 September 2017

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

1 reference

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9 September 2017

Histone acetylation and deacetylation: importance in inflammatory lung diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

9 September 2017

Signal transduction pathways and transcription factors as therapeutic targets in inflammatory disease: towards innovative antirheumatic therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

9 September 2017

Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

9 September 2017

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

1 reference

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9 September 2017

Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response.

1 reference

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9 September 2017

Forkhead-box transcription factors and their role in the immune system

1 reference

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9 September 2017

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages.

1 reference

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9 September 2017

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

1 reference

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9 September 2017

Activation of the STAT1 pathway in rheumatoid arthritis

1 reference

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9 September 2017

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications

1 reference

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9 September 2017

Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples from patients with end stage, destructive rheumatoid arthritis

1 reference

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9 September 2017

Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

1 reference

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9 September 2017

Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages

1 reference

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9 September 2017

Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

1 reference

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9 September 2017

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

1 reference

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9 September 2017

Histone deacetylases (HDACs): characterization of the classical HDAC family

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9 September 2017

Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65

1 reference

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9 September 2017

Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis

1 reference

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9 September 2017

Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes

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9 September 2017

Regional analysis of p53 mutations in rheumatoid arthritis synovium

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9 September 2017

The antitumor histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines

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9 September 2017

Negative control of p53 by Sir2alpha promotes cell survival under stress

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9 September 2017

Duration of nuclear NF-kappaB action regulated by reversible acetylation

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9 September 2017

Chromatin remodeling and transcriptional activation: the cast (in order of appearance).

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9 September 2017

Trichostatin A reverses skewed expression of CD154, interleukin-10, and interferon-gamma gene and protein expression in lupus T cells

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9 September 2017

Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.

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9 September 2017

Rheumatoid arthritis and p53: how oxidative stress might alter the course of inflammatory diseases.

1 reference

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9 September 2017

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

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9 September 2017

HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells

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14 September 2017

Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients

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14 September 2017

Inhibition of hypoxia-induced angiogenesis by trichostatin A via suppression of HIF-1a activity in human osteosarcoma

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14 September 2017

Class II histone deacetylases are associated with VHL-independent regulation of hypoxia-inducible factor 1 alpha

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14 September 2017

Up-regulation of MDR1 and induction of doxorubicin resistance by histone deacetylase inhibitor depsipeptide (FK228) and ATRA in acute promyelocytic leukemia cells

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14 September 2017

Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.

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14 September 2017

Expression profiling of sodium butyrate (NaB)-treated cells: identification of regulation of genes related to cytokine signaling and cancer metastasis by NaB.

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14 September 2017

Requirement of histone deacetylase activity for signaling by STAT1.

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14 September 2017

Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo

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14 September 2017

The effect of oxidative stress on histone acetylation and IL-8 release

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14 September 2017

Trichostatin A prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis

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26 June 2018

Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes

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2 September 2018

Epigenetic regulation of established human type 1 versus type 2 cytokine responses.

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2 September 2018

Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis

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2 September 2018

Deacetylase inhibition promotes the generation and function of regulatory T cells.

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2 September 2018

Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function.

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2 September 2018

Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1.

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2 September 2018

Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-beta production

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2 September 2018

Inflammatory arthritis requires Foxo3a to prevent Fas ligand-induced neutrophil apoptosis.

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2 September 2018

Decreased histone deacetylase activity in chronic obstructive pulmonary disease.

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2 September 2018

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation

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2 September 2018

Trichostatin A attenuates airway inflammation in mouse asthma model

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2 September 2018

Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression

1 reference

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2 September 2018

Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

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2 September 2018

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

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2 September 2018

Valproic acid inhibits angiogenesis in vitro and in vivo

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2 September 2018

A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis

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2 September 2018

Antitumor efficacy of FK228, a novel histone deacetylase inhibitor, depends on the effect on expression of angiogenesis factors

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2 September 2018

Serine phosphorylation of STAT3 is essential for Mcl-1 expression and macrophage survival

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2 September 2018

Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines

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2 September 2018

Expression and activity of histone deacetylases in human asthmatic airways

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

2 September 2018

Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

2 September 2018

Low-dose prednisone therapy for patients with early active rheumatoid arthritis: clinical efficacy, disease-modifying properties, and side effects: a randomized, double-blind, placebo-controlled clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

2 September 2018

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

2 September 2018

p53 overexpression in synovial tissue from patients with early and longstanding rheumatoid arthritis compared with patients with reactive arthritis and osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

2 September 2018

Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2592777

3 December 2018

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

1 reference

https://pubmed.ncbi.nlm.nih.gov/18983693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linking angiogenesis to bone destruction in arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18983693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

sirt1-null mice develop an autoimmune-like condition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18983693

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

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Multilingual sites(0 entries)

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