(Q36099479)

12 August 2017

Rational design of p53, an intrinsically unstructured protein, for the fabrication of novel molecular sensors (English)

1 reference

12 August 2017

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Melissa L Geddie

1

1 reference

12 August 2017

Taryn L O'Loughlin

series ordinal

2

1 reference

12 August 2017

Kristen K Woods

series ordinal

3

1 reference

12 August 2017

Ichiro Matsumura

series ordinal

4

1 reference

12 August 2017

language of work or name

English

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publication date

23 August 2005

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Journal of Biological Chemistry

12 August 2017

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12 August 2017

280

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12 August 2017

42

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12 August 2017

35641-35646

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The interplay between structure and function in intrinsically unstructured proteins.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Intermolecular complementation achieves high-specificity tumor targeting by anthrax toxin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

The p53 pathway: positive and negative feedback loops

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Intrinsically unstructured proteins and their functions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

DisProt: a database of protein disorder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Rapid evolution of beta-glucuronidase specificity by saturation mutagenesis of an active site loop

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Protein fragment complementation strategies for biochemical network mapping

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Allosteric enzymes as biosensors for molecular diagnosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Reprogramming control of an allosteric signaling switch through modular recombination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Intrinsically unstructured proteins evolve by repeat expansion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Chemical complementation: a reaction-independent genetic assay for enzyme catalysis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Protein engineering 20 years on.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

p53 contains large unstructured regions in its native state

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

In vitro evolution of thermostable p53 variants

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Progress and variations in two-hybrid and three-hybrid technologies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Engineering a regulatable enzyme for homogeneous immunoassays

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

The green fluorescent protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Engineering green fluorescent protein for improved brightness, longer wavelengths and fluorescence resonance energy transfer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Allosteric regulation of the thermostability and DNA binding activity of human p53 by specific interacting proteins. CRC Cell Transformation Group

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Allosteric activation of latent p53 tetramers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

A molecular sensor system based on genetically engineered alkaline phosphatase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Molecular cloning of sequence-specific DNA binding proteins using recognition site probes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

beta-Galactosidase containing a human immunodeficiency virus protease cleavage site is cleaved and inactivated by human immunodeficiency virus protease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Oncogenic forms of p53 inhibit p53-regulated gene expression

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

A transcriptionally active DNA-binding site for human p53 protein complexes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Regulation of the specific DNA binding function of p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Inhibition of viral and cellular promoters by human wild-type p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Definition of a consensus binding site for p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045634

Enhanced response to antibody binding in engineered beta-galactosidase enzymatic sensors.

2 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508149200

HIV-1 protease variants from 100-fold drug resistant clinical isolates: expression, purification, and crystallization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508149200

Proteolytic processing of HIV-1 protease precursor, kinetics and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508149200

Cooperative binding of tetrameric p53 to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508149200

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508149200

Screening patients for heterozygous p53 mutations using a functional assay in yeast

21 January 2018

1 reference

12 December 2020

Structural and kinetic analysis of p53-DNA complexes and comparison of human and murine p53

1 reference

12 December 2020

Engineering of solvent-exposed loops in Escherichia coli β-galactosidase

1 reference

12 December 2020

Optimized production and purification of Bacillus anthracis lethal factor

1 reference

12 December 2020

Development of a p53 responsive GFP reporter; identification of live cells with p53 activity

1 reference

12 December 2020

The C-terminus of p53: the more you learn the less you know

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M508149200

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

16118206

1 reference