(Q36202203)

12 August 2017

1 reference

title

CD4-CD8 lineage commitment: an inside view (English)

1 reference

12 August 2017

1 reference

1

Dietmar J Kappes

1 reference

12 August 2017

Xiao He

2

1 reference

12 August 2017

Xi He

series ordinal

3

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 August 2005

1 reference

12 August 2017

1 reference

12 August 2017

volume

6

1 reference

12 August 2017

issue

8

1 reference

12 August 2017

page(s)

761-766

1 reference

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection.

12 August 2017

cites work

1 reference

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

21 January 2018

1 reference

Intermediate steps in positive selection: differentiation of CD4+8int TCRint thymocytes into CD4-8+TCRhi thymocytes

21 January 2018

1 reference

Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes.

21 January 2018

1 reference

Another view of the selective model of thymocyte selection.

21 January 2018

1 reference

A human CD4 transgene rescues CD4-CD8+ cells in beta 2-microglobulin-deficient mice.

21 January 2018

1 reference

Stochastic component to development of class I major histocompatibility complex-specific T cells

21 January 2018

1 reference

Thymic selection in CD8 transgenic mice supports an instructive model for commitment to a CD4 or CD8 lineage.

21 January 2018

1 reference

T-cell development and the CD4-CD8 lineage decision

21 January 2018

1 reference

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

21 January 2018

1 reference

Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathways

21 January 2018

1 reference

Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules

21 January 2018

1 reference

Lck activity controls CD4/CD8 T cell lineage commitment.

21 January 2018

1 reference

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

1 reference

The influence of the MAPK pathway on T cell lineage commitment

21 January 2018

1 reference

The Ras/MAPK cascade and the control of positive selection

21 January 2018

1 reference

The duration of antigen receptor signalling determines CD4+ versus CD8+ T-cell lineage fate.

21 January 2018

1 reference

Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo.

21 January 2018

1 reference

Visualization of CD4/CD8 T cell commitment

21 January 2018

1 reference

The regulation of CD4 and CD8 coreceptor gene expression during T cell development

21 January 2018

1 reference

T cell development: bottoms-up

21 January 2018

1 reference

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

21 January 2018

1 reference

Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

21 January 2018

1 reference

An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells.

21 January 2018

1 reference

Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.

21 January 2018

1 reference

Hierarchical interactions of control elements determine CD8alpha gene expression in subsets of thymocytes and peripheral T cells.

21 January 2018

1 reference

Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

21 January 2018

1 reference

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

21 January 2018

1 reference

Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

21 January 2018

1 reference

Morpholino antisense oligonucleotide-mediated gene knockdown during thymocyte development reveals role for Runx3 transcription factor in CD4 silencing during development of CD4-/CD8+ thymocytes

21 January 2018

1 reference

Localization of the domains in Runx transcription factors required for the repression of CD4 in thymocytes

21 January 2018

1 reference

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

21 January 2018

1 reference

Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter

21 January 2018

1 reference

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

21 January 2018

1 reference

A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia

21 January 2018

1 reference

The CD8 population in CD4-deficient mice is heavily contaminated with MHC class II-restricted T cells

21 January 2018

1 reference

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

21 January 2018

1 reference

Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development

21 January 2018

1 reference

Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

21 January 2018

1 reference

Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.

21 January 2018

1 reference

Dynamic repositioning of CD4 and CD8 genes during T cell development.

21 January 2018

1 reference

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

21 January 2018

1 reference

The CD8alpha gene locus is regulated by the Ikaros family of proteins.

21 January 2018

1 reference

Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin

21 January 2018

1 reference

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

21 January 2018

1 reference

The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment.

21 January 2018

1 reference

HD mice: a novel mouse mutant with a specific defect in the generation of CD4(+) T cells

21 January 2018

1 reference

Regulation of lineage commitment distinct from positive selection.

21 January 2018

1 reference

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection

21 January 2018

1 reference

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

1 reference

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.

21 January 2018

1 reference

c-Krox, a transcriptional regulator of type I collagen gene expression, is preferentially expressed in skin

21 January 2018

1 reference

Cloning and characterization of hcKrox, a transcriptional regulator of extracellular matrix gene expression

21 January 2018

1 reference

Enforced expression of GATA-3 during T cell development inhibits maturation of CD8 single-positive cells and induces thymic lymphoma in transgenic mice.

21 January 2018

1 reference

Critical roles for transcription factor GATA-3 in thymocyte development

21 January 2018

1 reference

The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression

21 January 2018

1 reference

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

21 January 2018

1 reference

TOX: an HMG box protein implicated in the regulation of thymocyte selection

21 January 2018

1 reference

TOX provides a link between calcineurin activation and CD8 lineage commitment

21 January 2018

1 reference

Notch signaling in lymphocyte development and function

21 January 2018

1 reference

Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development

21 January 2018

1 reference

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling

21 January 2018

1 reference

Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

21 January 2018

1 reference

7 January 2021

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

7 January 2021

A transcriptional silencer controls the developmental expression of the CD4 gene.

1 reference

7 January 2021

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

1 reference

7 January 2021

A region in the CD8 gene locus that directs expression to the mature CD8 T cell subset in transgenic mice

1 reference

7 January 2021

Overexpression of AML1 transcription factor drives thymocytes into the CD8 single-positive lineage

1 reference

7 January 2021

Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage

1 reference

7 January 2021

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

7 January 2021

Programming for cytotoxic effector function occurs concomitantly with CD4 extinction during CD8(+) T cell differentiation in the thymus

1 reference

7 January 2021

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1230

1 reference

Dimensions Publication ID

12 August 2017

1033473187

0 references

1 reference