(Q36216684)

12 August 2017

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title

P53 in cancer: a paradigm for modern management of cancer (English)

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12 August 2017

Steele RJ

1

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12 August 2017

Lane DP

series ordinal

2

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12 August 2017

publication date

1 June 2005

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Journal of the Royal College of Surgeons of Edinburgh

12 August 2017

published in

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12 August 2017

volume

3

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12 August 2017

issue

3

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12 August 2017

page(s)

197-205

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https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

12 August 2017

1 reference

7 January 2021

Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

High-frequency developmental abnormalities in p53-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A subset of p53-deficient embryos exhibit exencephaly

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A teratologic suppressor role for p53 in benzo(a)pyrene–treated transgenic p53-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53-dependent apoptosis suppresses radiation-induced teratogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Tumor suppressors: a developing role for p53?

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A death-associated protein kinase (DAPK)-interacting protein, DIP-1, is an E3 ubiquitin ligase that promotes tumor necrosis factor-induced apoptosis and regulates the cellular levels of DAPK

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Regulation of p53 activity through lysine methylation

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

1 reference

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

1 reference

7 January 2021

Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A novel protein with strong homology to the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Identification of RB18A, a 205 kDa new p53 regulatory protein which shares antigenic and functional properties with p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family?

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Oncogenic forms of p53 inhibit p53-regulated gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Sunburn and p53 in the onset of skin cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The multistep nature of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Increased expression of mutant forms of p53 oncogene in primary lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53 in tumour pathology: can we trust immunohistochemistry?--Revisited!

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Potential false-positive results with antigen enhancement for immunohistochemistry of the p53 gene product in colorectal neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

The candidate tumour suppressor p33ING1 cooperates with p53 in cell growth control

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

P53 abnormalities and outcomes in colorectal cancer: a systematic review.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

p53 mutations increase resistance to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Detecting colorectal cancer in stool with the use of multiple genetic targets

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Cancer and mutant DNA in blood plasma

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Novel combination therapy for human colon cancer with adenovirus-mediated wild-type p53 gene transfer and DNA-damaging chemotherapeutic agent

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

A phase I open-label, dose-escalation, multi-institutional trial of injection with an E1B-Attenuated adenovirus, ONYX-015, into the peritumoral region of recurrent malignant gliomas, in the adjuvant setting.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Phase I-II trial of ONYX-015 in combination with MAP chemotherapy in patients with advanced sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Regulation of the Cryptic Sequence-specific DNA-binding Function of p53 by Protein Kinases

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

Small peptides activate the latent sequence-specific DNA binding function of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS1479-666X%2805%2980041-1

7 January 2021

10.1016/S1479-666X(05)80041-1

Identifiers

DOI

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