(Q36245338)

13 August 2017

1 reference

title

Artificial and engineered chromosomes: developments and prospects for gene therapy (English)

1 reference

13 August 2017

0 references

Brenda R Grimes

1

1 reference

13 August 2017

Zoia Larin Monaco

series ordinal

2

1 reference

13 August 2017

language of work or name

1 reference

1 September 2005

1 reference

13 August 2017

1 reference

13 August 2017

volume

114

1 reference

13 August 2017

issue

4

1 reference

13 August 2017

page(s)

230-241

1 reference

https://scigraph.springernature.com/pub.10.1007/s00412-005-0017-5

13 August 2017

exact match

0 references

cites work

Alpha-satellite DNA of primates: old and new families

1 reference

12 December 2020

An unpaired mouse centromere passes consistently through male meiosis and does not significantly compromise spermatogenesis.

1 reference

12 December 2020

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

1 reference

12 December 2020

Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase

1 reference

12 December 2020

Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts

1 reference

12 December 2020

Determining centromere identity: cyclical stories and forking paths.

1 reference

12 December 2020

Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector.

1 reference

12 December 2020

Functional complementation of a genetic deficiency with human artificial chromosomes.

1 reference

12 December 2020

Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 - new vectors for in vitro and in vivo delivery

1 reference

12 December 2020

Chromosome-based vectors for Mammalian cells: an overview.

1 reference

12 December 2020

The role of CENP-B and alpha-satellite DNA: de novo assembly and epigenetic maintenance of human centromeres

1 reference

12 December 2020

Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice

1 reference

12 December 2020

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

1 reference

12 December 2020

The roles of histone modifications and small RNA in centromere function.

1 reference

12 December 2020

The accuracy of segregation of human mini-chromosomes varies in different vertebrate cell lines, correlates with the extent of centromere formation and provides evidence for a trans-acting centromere maintenance activity

1 reference

12 December 2020

Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts

1 reference

12 December 2020

Recombining overlapping BACs into a single larger BAC

1 reference

12 December 2020

Mouse centric and pericentric satellite repeats form distinct functional heterochromatin

1 reference

12 December 2020

Construction of a novel expression system on a human artificial chromosome.

1 reference

12 December 2020

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array

1 reference

12 December 2020

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

1 reference

12 December 2020

Efficiency of de novo centromere formation in human artificial chromosomes

1 reference

12 December 2020

Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection.

1 reference

12 December 2020

Domain organization at the centromere and neocentromere

1 reference

12 December 2020

Mammalian artificial chromosome formation from circular alphoid input DNA does not require telomere repeats

1 reference

12 December 2020

Alpha-satellite DNA and vector composition influence rates of human artificial chromosome formation

1 reference

12 December 2020

Generation of human artificial chromosomes expressing naturally controlled guanosine triphosphate cyclohydrolase I gene

1 reference

12 December 2020

Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin

1 reference

12 December 2020

Chromosome engineering: prospects for gene therapy

1 reference

12 December 2020

Making sense of eukaryotic DNA replication origins

1 reference

12 December 2020

Genomic and genetic definition of a functional human centromere

1 reference

12 December 2020

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

1 reference

12 December 2020

Chromosomal dynamics of human neocentromere formation

1 reference

12 December 2020

Transcription within a functional human centromere

1 reference

12 December 2020

Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag

1 reference

12 December 2020

Efficient combination of large DNA in vitro: in gel site specific recombination (IGSSR) of PAC fragments containing alpha satellite DNA and the human HPRT gene locus

1 reference

12 December 2020

Human artificial chromosomes containing chromosome 17 alphoid DNA maintain an active centromere in murine cells but are not stable

1 reference

12 December 2020

Analysis of the centromeric regions of the human genome assembly

1 reference

12 December 2020

Assay of centromere function using a human artificial chromosome

1 reference

12 December 2020

Chromosome-specific subsets of human alpha satellite DNA: analysis of sequence divergence within and between chromosomal subsets and evidence for an ancestral pentameric repeat

1 reference

12 December 2020

Epigenetic assembly of centromeric chromatin at ectopic alpha-satellite sites on human chromosomes

1 reference

12 December 2020

Mammalian artificial chromosome pilot production facility: large-scale isolation of functional satellite DNA-based artificial chromosomes

1 reference

12 December 2020

Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD).

1 reference

12 December 2020

Use of natural and artificial chromosome vectors for animal transgenesis

1 reference

12 December 2020

Assembly and characterization of heterochromatin and euchromatin on human artificial chromosomes

1 reference

12 December 2020

Use of a human minichromosome as a cloning and expression vector for mammalian cells

1 reference

12 December 2020

A phage integrase directs efficient site-specific integration in human cells

1 reference

12 December 2020

Advances in human artificial chromosome technology

1 reference

12 December 2020

Stable gene expression from a mammalian artificial chromosome

1 reference

12 December 2020

Construction of YAC-based mammalian artificial chromosomes

1 reference

12 December 2020

Neocentromeres: role in human disease, evolution, and centromere study

1 reference

12 December 2020

Construction of a novel human artificial chromosome vector for gene delivery

1 reference

12 December 2020

Localization and phosphorylation of HP1 proteins during the cell cycle in mammalian cells

1 reference

12 December 2020

A structurally defined mini-chromosome vector for the mouse germ line.

1 reference

12 December 2020

A solid foundation: functional specialization of centromeric chromatin

1 reference

12 December 2020

Suitability of a CMV/EGFP cassette to monitor stable expression from human artificial chromosomes but not transient transfer in the cells forming viable clones

1 reference

12 December 2020

Double trans-chromosomic mice: maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies

1 reference

12 December 2020

Sex matters in meiosis

1 reference

12 December 2020

Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals

1 reference

12 December 2020

Stability of transferred human chromosome fragments in cultured cells and in mice

1 reference

12 December 2020

Telomere directed fragmentation of mammalian chromosomes

1 reference

12 December 2020

Construction of human artificial chromosome vectors by recombineering.

1 reference

12 December 2020

Conserved organization of centromeric chromatin in flies and humans

1 reference

12 December 2020

Pronuclear microinjection of purified artificial chromosomes for generation of transgenic mice: pick-and-inject technique

1 reference

12 December 2020

Retrofitting vectors for Escherichia coli-based artificial chromosomes (PACs and BACs) with markers for transfection studies

1 reference

12 December 2020

DNA modification and functional delivery into human cells using Escherichia coli DH10B.

1 reference

12 December 2020

A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy

1 reference

12 December 2020

Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice.

1 reference

12 December 2020

Efficient male and female germline transmission of a human chromosomal vector in mice

1 reference

12 December 2020

Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.

1 reference

12 December 2020

Mice containing a human chromosome 21 model behavioral impairment and cardiac anomalies of Down's syndrome.

1 reference

12 December 2020

Building the centromere: from foundation proteins to 3D organization.

1 reference

12 December 2020

Gene therapy: twenty-first century medicine

1 reference

12 December 2020

A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA

1 reference

12 December 2020

Gene therapy progress and prospects: episomally maintained self-replicating systems.

1 reference

12 December 2020

The Assembly of Large BACs by in Vivo Recombination

1 reference

12 December 2020

Functional reintroduction of human telomeres into mammalian cells

1 reference

12 December 2020

Insertion of a loxP site in a size-reduced human accessory chromosome

1 reference

12 December 2020

Strategies for engineering human chromosomes with therapeutic potential

1 reference

12 December 2020

Localisation of centromeric proteins to a fraction of mouse minor satellite DNA on a mini-chromosome in human, mouse and chicken cells

1 reference

12 December 2020

The role of Drosophila CID in kinetochore formation, cell-cycle progression and heterochromatin interactions

1 reference

12 December 2020

Generation of an approximately 2.4 Mb human X centromere-based minichromosome by targeted telomere-associated chromosome fragmentation in DT40.

1 reference

12 December 2020

Purification of the centromere-specific protein CENP-A and demonstration that it is a distinctive histone

1 reference

12 December 2020

Functional human CFTR produced by a stable minichromosome

1 reference

12 December 2020

Functional gene transfer from intracellular bacteria to mammalian cells

1 reference

12 December 2020

Towards safe, non-viral therapeutic gene expression in humans.

1 reference

12 December 2020

Sequencing of a rice centromere uncovers active genes

1 reference

12 December 2020

Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays

1 reference

12 December 2020

Human mini-chromosomes with minimal centromeres

1 reference

12 December 2020

Functional expression and germline transmission of a human chromosome fragment in chimaeric mice

1 reference

12 December 2020

CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.

1 reference

12 December 2020

Dicer is essential for formation of the heterochromatin structure in vertebrate cells

1 reference

12 December 2020

Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling

1 reference

12 December 2020

10.1007/S00412-005-0017-5

Identifiers

DOI

1 reference

13 August 2017

1 reference